Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C645_RS02010 Genome accession   NZ_CP008740
Coordinates   408822..410042 (-) Length   406 a.a.
NCBI ID   WP_046067577.1    Uniprot ID   -
Organism   Haemophilus influenzae 2019     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 403822..415042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C645_RS01965 (C645_01990) - 404449..404655 (-) 207 WP_005656254.1 heavy-metal-associated domain-containing protein -
  C645_RS01970 (C645_01995) - 404729..404935 (-) 207 WP_005656255.1 heavy-metal-associated domain-containing protein -
  C645_RS01975 (C645_02000) - 405009..405215 (-) 207 WP_005656257.1 heavy-metal-associated domain-containing protein -
  C645_RS01980 (C645_02005) - 405289..405495 (-) 207 WP_005660027.1 heavy-metal-associated domain-containing protein -
  C645_RS01985 (C645_02010) - 405569..405775 (-) 207 WP_005689491.1 heavy-metal-associated domain-containing protein -
  C645_RS01990 (C645_02015) cueR 405852..406238 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  C645_RS01995 (C645_02020) metJ 406252..406569 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  C645_RS02000 (C645_02025) rho 406817..408079 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  C645_RS02005 (C645_02030) pilD 408133..408825 (-) 693 WP_046067576.1 prepilin peptidase Machinery gene
  C645_RS02010 (C645_02035) pilC 408822..410042 (-) 1221 WP_046067577.1 type II secretion system F family protein Machinery gene
  C645_RS02015 (C645_02040) pilB 410039..411433 (-) 1395 WP_005656265.1 GspE/PulE family protein Machinery gene
  C645_RS02020 (C645_02045) pilA 411430..411879 (-) 450 WP_005656280.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  C645_RS02025 (C645_02050) ampD 411994..412554 (+) 561 WP_005648974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  C645_RS02030 (C645_02055) corC 413175..414074 (+) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46208.50 Da        Isoelectric Point: 9.9012

>NTDB_id=123947 C645_RS02010 WP_046067577.1 408822..410042(-) (pilC) [Haemophilus influenzae 2019]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISHGLTHIKLQQNWQFGAKPKSSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIILNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSVVCKKIATHRSQSLALQRKLQK
IMLYPLMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFVLSFFLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALESFLPRTQTWQTKKTLVNDMVLDKEVRSILQWVSQG
YAFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIAENYQAKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=123947 C645_RS02010 WP_046067577.1 408822..410042(-) (pilC) [Haemophilus influenzae 2019]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAATTAATAAGCCACGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAGTTCAGAAATTAGCGAATTACTCAATCAATTAGCAACATTGCTACAGTCCGCTATTCCGTTAAAAAACAGTCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATACTCAATGAATGGCTTGAACGACTACTTCAATCTATTGAATCTGGTTT
AGCATTCTCACAAGCCATTGAACAACAAGGGAAATATCTCACTCAACAAGAAATTCAACTGATTCAAGTAGGAGAAATGA
CTGGCAAACTTTCCGTAGTTTGTAAAAAAATAGCCACGCATCGTAGCCAATCTTTAGCATTGCAACGTAAATTACAGAAA
ATTATGTTATATCCCTTAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTACTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCAATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGTTTTGAGTTTTTTTCTATTTTATTATTTCTATTTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAGCTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAAGCACTAGAGAGTTTTCTTCCTCGCACACAAACTT
GGCAAACCAAGAAAACGCTTGTAAACGATATGGTATTAGATAAAGAAGTGCGGTCAATTTTGCAATGGGTTTCTCAAGGC
TATGCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAGCAAAGCGG
AAAACTCGCTTTGATGCTAGAACATATTGCGGAAAATTACCAAGCAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGATCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Haemophilus influenzae Rd KW20

97.291

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.155

98.768

0.377

Multiple sequence alignment