Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | NTHIC486_RS03440 | Genome accession | NZ_CP007471 |
| Coordinates | 675398..675847 (+) | Length | 149 a.a. |
| NCBI ID | WP_005686726.1 | Uniprot ID | - |
| Organism | Haemophilus influenzae strain C486 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 670398..680847
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NTHIC486_RS03420 (NTHIC486_00684) | rsmE | 670862..671599 (-) | 738 | WP_044345403.1 | 16S rRNA (uracil(1498)-N(3))-methyltransferase | - |
| NTHIC486_RS03425 (NTHIC486_00685) | lnt | 671649..673178 (-) | 1530 | WP_080334644.1 | apolipoprotein N-acyltransferase | - |
| NTHIC486_RS03430 (NTHIC486_00686) | corC | 673201..674100 (-) | 900 | WP_044345407.1 | CNNM family magnesium/cobalt transport protein CorC | - |
| NTHIC486_RS03435 (NTHIC486_00687) | ampD | 674723..675283 (-) | 561 | WP_005648974.1 | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | - |
| NTHIC486_RS03440 (NTHIC486_00688) | pilA | 675398..675847 (+) | 450 | WP_005686726.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | Machinery gene |
| NTHIC486_RS03445 (NTHIC486_00689) | pilB | 675844..677241 (+) | 1398 | WP_005686724.1 | GspE/PulE family protein | Machinery gene |
| NTHIC486_RS03450 (NTHIC486_00690) | pilC | 677238..678455 (+) | 1218 | WP_005686722.1 | type II secretion system F family protein | Machinery gene |
| NTHIC486_RS03455 (NTHIC486_00691) | pilD | 678452..679144 (+) | 693 | WP_005686720.1 | prepilin peptidase | Machinery gene |
| NTHIC486_RS03460 (NTHIC486_00692) | rho | 679198..680460 (-) | 1263 | WP_005648966.1 | transcription termination factor Rho | - |
Sequence
Protein
Download Length: 149 a.a. Molecular weight: 15542.90 Da Isoelectric Point: 8.4607
>NTDB_id=119744 NTHIC486_RS03440 WP_005686726.1 675398..675847(+) (pilA) [Haemophilus influenzae strain C486]
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAVSELLQASAPYKADVELCVYSTNEATKCTGGKNGIA
ADITTAKGYVKSVTTSNGAITVKGDGTLANMEYILQASGNAATGVTWTTTCKGTDASLFPANFCGSVTQ
MKLTTQQTLKKGFTLIELMIVIAIIAILATIAIPSYQNYTKKAAVSELLQASAPYKADVELCVYSTNEATKCTGGKNGIA
ADITTAKGYVKSVTTSNGAITVKGDGTLANMEYILQASGNAATGVTWTTTCKGTDASLFPANFCGSVTQ
Nucleotide
Download Length: 450 bp
>NTDB_id=119744 NTHIC486_RS03440 WP_005686726.1 675398..675847(+) (pilA) [Haemophilus influenzae strain C486]
ATGAAACTAACAACACAGCAAACCTTGAAAAAAGGGTTTACATTAATAGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATCCCCTCTTATCAAAATTATACTAAAAAAGCAGCGGTATCTGAATTACTGCAAGCGTCAGCGC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAGCAACAAAGTGTACGGGTGGAAAAAATGGTATTGCA
GCAGATATAACCACAGCAAAAGGCTATGTAAAATCAGTGACAACAAGCAACGGTGCAATAACAGTAAAAGGGGATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCCAGTGGTAATGCTGCAACAGGTGTAACTTGGACAACAACTTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCGGAAGTGTCACACAATGA
ATGAAACTAACAACACAGCAAACCTTGAAAAAAGGGTTTACATTAATAGAGCTAATGATTGTGATTGCAATTATTGCTAT
TTTAGCCACTATCGCAATCCCCTCTTATCAAAATTATACTAAAAAAGCAGCGGTATCTGAATTACTGCAAGCGTCAGCGC
CTTATAAGGCTGATGTGGAATTATGTGTATATAGCACAAATGAAGCAACAAAGTGTACGGGTGGAAAAAATGGTATTGCA
GCAGATATAACCACAGCAAAAGGCTATGTAAAATCAGTGACAACAAGCAACGGTGCAATAACAGTAAAAGGGGATGGCAC
ATTGGCAAATATGGAATATATTTTGCAAGCCAGTGGTAATGCTGCAACAGGTGTAACTTGGACAACAACTTGCAAAGGAA
CGGATGCCTCTTTATTTCCAGCAAATTTTTGCGGAAGTGTCACACAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Haemophilus influenzae 86-028NP |
97.987 |
100 |
0.98 |
| pilA | Haemophilus influenzae Rd KW20 |
91.275 |
100 |
0.913 |
| pilA | Glaesserella parasuis strain SC1401 |
54.362 |
100 |
0.544 |
| pilA2 | Legionella pneumophila strain ERS1305867 |
42.446 |
93.289 |
0.396 |
| pilA2 | Legionella pneumophila str. Paris |
42.446 |
93.289 |
0.396 |
| pilA | Vibrio campbellii strain DS40M4 |
39.716 |
94.631 |
0.376 |