Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   ACLV7H_RS09920 Genome accession   NZ_OZ217340
Coordinates   1948336..1948461 (-) Length   41 a.a.
NCBI ID   WP_000799678.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 1943336..1953461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS09895 (SORA22_19940) - 1945470..1946012 (+) 543 WP_411867057.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -
  ACLV7H_RS09910 (SORA22_19970) comE 1946247..1946999 (-) 753 WP_045592607.1 competence system response regulator transcription factor ComE Regulator
  ACLV7H_RS09915 (SORA22_19980) comD 1946996..1948315 (-) 1320 Protein_1906 competence system sensor histidine kinase ComD -
  ACLV7H_RS09920 (SORA22_19990) comC/comC2 1948336..1948461 (-) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  ACLV7H_RS09930 (SORA22_20010) rlmH 1948743..1949222 (-) 480 WP_411867058.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ACLV7H_RS09935 (SORA22_20020) htrA 1949409..1950602 (+) 1194 WP_411867059.1 S1C family serine protease Regulator
  ACLV7H_RS09940 (SORA22_20030) spo0J 1950660..1951418 (+) 759 WP_411867060.1 ParB/RepB/Spo0J family partition protein Regulator
  ACLV7H_RS09945 - 1951635..1952063 (+) 429 Protein_1911 hypothetical protein -

Sequence


Protein


Download         Length: 41 a.a.        Molecular weight: 4960.73 Da        Isoelectric Point: 10.3052

>NTDB_id=1169994 ACLV7H_RS09920 WP_000799678.1 1948336..1948461(-) (comC/comC2) [Streptococcus oralis isolate S. oralis A22]
MKNTVKLEQFKEVTEAELQEIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=1169994 ACLV7H_RS09920 WP_000799678.1 1948336..1948461(-) (comC/comC2) [Streptococcus oralis isolate S. oralis A22]
ATGAAGAATACAGTAAAGTTGGAACAATTTAAAGAGGTAACAGAGGCAGAATTGCAGGAGATTCGGGGTGGAGATTGGAG
AATTTCAGAAACAATTCGTAACCTTATTTTTCCAAGAAGAAAGTAA

Domains


Predicted by InterproScan.

(1-29)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

56.098

100

0.561

  comC/comC2 Streptococcus pneumoniae TIGR4

56.098

100

0.561

  comC Streptococcus mitis SK321

56.098

100

0.561

  comC/comC1 Streptococcus pneumoniae R6

53.659

100

0.537

  comC/comC1 Streptococcus pneumoniae G54

53.659

100

0.537

  comC/comC1 Streptococcus pneumoniae D39

53.659

100

0.537

  comC/comC1 Streptococcus pneumoniae Rx1

53.659

100

0.537

  comC Streptococcus mitis NCTC 12261

47.5

97.561

0.463

  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39

  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366


Multiple sequence alignment