Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AB3224_RS04030 Genome accession   NZ_OZ061585
Coordinates   855497..856747 (+) Length   416 a.a.
NCBI ID   WP_011667974.1    Uniprot ID   M5AZ98
Organism   Levilactobacillus brevis isolate Levilactobacillus brevis CIRM-BIA2444     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 850497..861747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3224_RS04010 - 851205..852500 (+) 1296 WP_015473537.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  AB3224_RS04015 - 852478..853767 (+) 1290 WP_041815255.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  AB3224_RS04020 - 853881..854792 (+) 912 WP_239309669.1 helix-turn-helix domain-containing protein -
  AB3224_RS04025 pgsA 854854..855441 (+) 588 WP_011668109.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AB3224_RS04030 cinA 855497..856747 (+) 1251 WP_011667974.1 competence/damage-inducible protein A Machinery gene
  AB3224_RS04035 recA 856841..857974 (+) 1134 WP_011667973.1 recombinase RecA Machinery gene
  AB3224_RS04040 - 858057..858209 (-) 153 WP_011667972.1 hypothetical protein -
  AB3224_RS04045 rny 858537..860096 (+) 1560 WP_011667971.1 ribonuclease Y -
  AB3224_RS04050 - 860228..861022 (+) 795 WP_011667970.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44778.88 Da        Isoelectric Point: 5.2849

>NTDB_id=1166325 AB3224_RS04030 WP_011667974.1 855497..856747(+) (cinA) [Levilactobacillus brevis isolate Levilactobacillus brevis CIRM-BIA2444]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDQDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=1166325 AB3224_RS04030 WP_011667974.1 855497..856747(+) (cinA) [Levilactobacillus brevis isolate Levilactobacillus brevis CIRM-BIA2444]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGCGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGCTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAACCCTTAGCAAATCGGACTGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCAGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGGAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCGGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGTACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACAATTGATCAAGATGGTGTGGTTAGTGCGGCCACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGCTGGA
TACTGATTTTTCGTTGAGCTTCACGGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGGCAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB M5AZ98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.471

100

0.445

Multiple sequence alignment