Detailed information NTG1161716

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: U8955_RS04055
• Genome accession: NZ_OY769914
• Coordinates: 801289..801939 (+)
• Length: 216 a.a.
• NCBI ID: WP_038805079.1
• Uniprot ID: A0A7T2ZVA7
• Organism: Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 796289..806939

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8955_RS04025 (SDENT7746_04045)	cvfB	796564..797418 (+)	855	WP_038805072.1	RNA-binding virulence regulatory protein CvfB	-
U8955_RS04030 (SDENT7746_04050)	-	797430..798035 (+)	606	WP_038805073.1	GrpB family protein	-
U8955_RS04035 (SDENT7746_04055)	-	798032..798247 (+)	216	WP_038805074.1	YozE family protein	-
U8955_RS04040 (SDENT7746_04060)	-	798328..799314 (+)	987	WP_038805075.1	PhoH family protein	-
U8955_RS04045 (SDENT7746_04065)	ald	799364..800476 (-)	1113	WP_038805076.1	alanine dehydrogenase	-
U8955_RS04050 (SDENT7746_04070)	-	800653..801222 (+)	570	WP_038805078.1	GNAT family N-acetyltransferase	-
U8955_RS04055 (SDENT7746_04075)	comEA/celA/cilE	801289..801939 (+)	651	WP_038805079.1	helix-hairpin-helix domain-containing protein	Machinery gene
U8955_RS04060 (SDENT7746_04080)	comEC/celB	801923..804163 (+)	2241	WP_038805080.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
U8955_RS04065 (SDENT7746_04085)	infC	804383..804913 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
U8955_RS04070 (SDENT7746_04090)	rpmI	804946..805146 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
U8955_RS04075 (SDENT7746_04095)	rplT	805198..805557 (+)	360	WP_000124830.1	50S ribosomal protein L20	-
U8955_RS04080 (SDENT7746_04100)	-	805616..805996 (+)	381	WP_038805081.1	VOC family protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23179.42 Da
• Isoelectric Point: 5.9284

>NTDB_id=1161716 U8955_RS04055 WP_038805079.1 801289..801939(+) (comEA/celA/cilE) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MEVIIEKIKEYKIIVICAGLGLALGGFFLLKPTSQTPVKETNLQAEVAAVSKDSSSEKEVKKEEKEESPEQDLITVDVKG
AVKSPGIYDLPLGSRVHDAVQKAGGLTEEADSKSLNLAQKISDEALVYVPTKGEEAASQQAASGTSPSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=1161716 U8955_RS04055 WP_038805079.1 801289..801939(+) (comEA/celA/cilE) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGGAAGTCATTATCGAGAAAATCAAAGAATATAAAATCATTGTCATCTGTGCTGGCTTGGGTTTAGCCTTAGGCGGATT
TTTCCTGCTAAAGCCAACTTCACAAACACCTGTGAAAGAAACAAATTTGCAGGCTGAAGTTGCGGCCGTTTCAAAGGATT
CATCGTCTGAAAAGGAAGTCAAGAAGGAAGAAAAGGAAGAGTCTCCTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTCTTGGCAGTCGAGTTCACGATGCCGTTCAGAAGGCGGGTGGCTTGAC
AGAAGAAGCAGACAGCAAGTCGCTTAATCTAGCACAGAAAATCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGCAGCTAGTCAGCAGGCTGCCTCTGGAACGTCTCCTTCGACAAGTAAAGAAAAGAAGGTCAACCTCAATAAAGCC
AGTCTGGAAGAACTCAAGCAGGTCAAAGGCTTGGGAGGAAAACGAGCACAGGATATTATCGACCATCGTGAGGCGAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAAGTCTCTGGCATTGGCGCTAAGACCATAGAAAAGCTAAAAGATTATGTCA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-127)

• Helix-hairpin-helix motif (HHH_3) (151-214)

3D structure

• AlphaFold DB: A0A7T2ZVA7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	91.667	100	0.917
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	91.204	100	0.912
comEA/celA/cilE	Streptococcus pneumoniae D39	89.352	100	0.894
comEA/celA/cilE	Streptococcus pneumoniae R6	89.352	100	0.894
comEA/celA/cilE	Streptococcus pneumoniae Rx1	89.352	100	0.894
comEA/celA/cilE	Streptococcus mitis SK321	87.5	100	0.875
comEA	Lactococcus lactis subsp. cremoris KW2	40.991	100	0.421
comEA	Streptococcus thermophilus LMD-9	39.524	97.222	0.384
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361