Detailed information NTG1161717

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: U8955_RS04060
• Genome accession: NZ_OY769914
• Coordinates: 801923..804163 (+)
• Length: 746 a.a.
• NCBI ID: WP_038805080.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 796923..809163

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8955_RS04030 (SDENT7746_04050)	-	797430..798035 (+)	606	WP_038805073.1	GrpB family protein	-
U8955_RS04035 (SDENT7746_04055)	-	798032..798247 (+)	216	WP_038805074.1	YozE family protein	-
U8955_RS04040 (SDENT7746_04060)	-	798328..799314 (+)	987	WP_038805075.1	PhoH family protein	-
U8955_RS04045 (SDENT7746_04065)	ald	799364..800476 (-)	1113	WP_038805076.1	alanine dehydrogenase	-
U8955_RS04050 (SDENT7746_04070)	-	800653..801222 (+)	570	WP_038805078.1	GNAT family N-acetyltransferase	-
U8955_RS04055 (SDENT7746_04075)	comEA/celA/cilE	801289..801939 (+)	651	WP_038805079.1	helix-hairpin-helix domain-containing protein	Machinery gene
U8955_RS04060 (SDENT7746_04080)	comEC/celB	801923..804163 (+)	2241	WP_038805080.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
U8955_RS04065 (SDENT7746_04085)	infC	804383..804913 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
U8955_RS04070 (SDENT7746_04090)	rpmI	804946..805146 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
U8955_RS04075 (SDENT7746_04095)	rplT	805198..805557 (+)	360	WP_000124830.1	50S ribosomal protein L20	-
U8955_RS04080 (SDENT7746_04100)	-	805616..805996 (+)	381	WP_038805081.1	VOC family protein	-
U8955_RS04085 (SDENT7746_04105)	-	806243..807043 (+)	801	WP_038805082.1	dihydroorotate dehydrogenase electron transfer subunit	-
U8955_RS04090 (SDENT7746_04110)	-	807006..807992 (+)	987	WP_080641291.1	dihydroorotate dehydrogenase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84494.79 Da
• Isoelectric Point: 9.2903

>NTDB_id=1161717 U8955_RS04060 WP_038805080.1 801923..804163(+) (comEC/celB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MSQWIKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSAGKVLAICGVFGFWFLFQTWQQTQASQN
LVDSVEKVKILPDTIKVNGDSLSFRGKADGHTFQVYYKLQSEEEKEQFQTLTDLHEIELEGKVSEPEGQRNFGGFNYQAY
LKTQGIYQTLTIKRIQSVKQISSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGIKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPITQLNLVFEWLEDIIRLVSQLASRPLVFGQPNAWLLILLLISLAILYDFRKNIKRVAGVSLLIIGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKAILIDVGGKAESDKKIEKWQEKATTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGILTQKEFVAELEASQTKVRSVTAGENLPIFGSQLEVLSPRQIGDGDRDGSLVLYGKL
LDKHFLFTGNLKEKGEKDILKQYPNLEVDVLKVGQHGSKTSSNPAFLEKLKPEISLISVGKNNRAKLPHQETLTRLETIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1161717 U8955_RS04060 WP_038805080.1 801923..804163(+) (comEC/celB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGTCACAGTGGATTAAGAATTTCCCTATTCCTCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTTCAATTTCCTTGGAAATCTGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAACTTGGCAACAGACACAAGCTAGTCAAAAC
CTAGTGGATTCTGTTGAAAAGGTGAAGATCTTGCCTGATACCATCAAAGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGACGGCCATACCTTCCAAGTTTACTATAAACTCCAGTCTGAGGAGGAGAAAGAGCAATTTCAAACCTTAACAGATC
TTCATGAGATTGAACTAGAAGGGAAAGTTTCAGAGCCTGAAGGTCAGAGGAATTTTGGTGGATTTAACTACCAAGCCTAC
CTGAAGACTCAAGGGATTTACCAGACACTGACTATCAAGAGAATCCAGTCAGTTAAACAGATTAGCAGTTGGGATATAGG
TGAAAATTTATCAAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGACGCACTTTCCAGACCCTATGCGCAACTATATGA
CAGGTCTTCTGTTAGGACATCTGGATACGGACTTTGAGGAGATGAATGAACTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCTTGTCGGGTATGCAGGTGGGATTCTTTATGGATGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAGTGGCTGACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCAGTCATTCGCAGTC
TCTTGCAAAAGTTACTAGCACAACATGGTATTAAGGGCTTGGATAATTTTGCCTTGACAGTCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCTGGAGGGGTCTTGTCCTGCGCTTATGCTTTTATCTTGACTATGACAAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCCTTGGGAATATTGCCTATTTTGTCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCAATTCTTTTAACCTTTGTCTTTTCCTTTCTGTTTGATGTTGTCTTCTTGCCGCTTTTGTCCATC
TTATTTATTCTGTCTTTTGTTTACCCAATCACCCAGCTTAACCTTGTCTTTGAGTGGTTGGAGGACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCCCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTATTAATTTCCTTGGCAA
TACTGTATGATTTTAGGAAAAACATCAAAAGAGTAGCTGGAGTCAGCTTATTGATTATAGGTCTCTTTTTCCTAACCAAA
CATCCGCTGGAAAATGAAATCACCATGCTGGATGTCGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGTAAAGC
CATTCTCATAGATGTGGGAGGCAAGGCAGAGTCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGTGGGGTAGCCAAGATTGACCAGCTGATTTTGACCAACACAGATAAA
GAACATGTTGGAGATTTGCTGGAGGTGACCAAGGCTTTCCATGTTGGGGAGATTTTAGTATCAAAAGGAATTCTGACACA
GAAGGAATTTGTAGCAGAACTAGAAGCAAGCCAAACCAAGGTGCGCAGTGTGACAGCAGGGGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGCAGATTGGAGATGGAGATCGTGATGGTTCCCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTTACAGGAAACTTGAAAGAGAAGGGAGAGAAGGATATTCTAAAGCAATACCCTAACTTAGA
GGTGGATGTCTTGAAAGTCGGTCAACATGGTTCTAAAACATCATCAAATCCAGCTTTTCTAGAAAAACTTAAACCAGAGA
TTTCTCTCATCTCAGTTGGAAAGAACAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACTCGACTAGAGACCATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGAGCTATTCGCTTTAAAGGATGGAATAGTTGGCGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-457)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-638)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	88.472	100	0.885
comEC/celB	Streptococcus mitis NCTC 12261	88.322	99.866	0.882
comEC/celB	Streptococcus pneumoniae TIGR4	86.997	100	0.87
comEC/celB	Streptococcus pneumoniae D39	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae Rx1	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae R6	86.595	100	0.866
comEC	Lactococcus lactis subsp. cremoris KW2	45.074	99.33	0.448