Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   U8955_RS01635 Genome accession   NZ_OY769914
Coordinates   290483..291739 (+) Length   418 a.a.
NCBI ID   WP_038804175.1    Uniprot ID   A0A7T2ZXR8
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 285483..296739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS01615 (SDENT7746_01645) comM 287690..288313 (+) 624 WP_080641267.1 hypothetical protein Regulator
  U8955_RS01620 (SDENT7746_01650) tsaE 288417..288860 (+) 444 WP_000288225.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  U8955_RS01625 (SDENT7746_01655) - 288850..289371 (+) 522 WP_038804177.1 GNAT family N-acetyltransferase -
  U8955_RS01630 (SDENT7746_01660) brpA 289376..290410 (+) 1035 WP_038804176.1 biofilm formation/cell division transcriptional regulator BrpA -
  U8955_RS01635 (SDENT7746_01665) cinA 290483..291739 (+) 1257 WP_038804175.1 competence/damage-inducible protein A Machinery gene
  U8955_RS01640 (SDENT7746_01670) recA 291794..292945 (+) 1152 WP_038804174.1 recombinase RecA Machinery gene
  U8955_RS01645 (SDENT7746_01675) - 293002..293556 (-) 555 WP_038804172.1 GNAT family N-acetyltransferase -
  U8955_RS01650 (SDENT7746_01680) - 293666..295036 (+) 1371 WP_038804171.1 MATE family efflux transporter -
  U8955_RS01655 (SDENT7746_01685) - 295133..295849 (+) 717 WP_000532893.1 YebC/PmpR family DNA-binding transcriptional regulator -
  U8955_RS01660 (SDENT7746_01690) - 295897..296595 (-) 699 WP_038804170.1 CD20-like domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45124.57 Da        Isoelectric Point: 4.9057

>NTDB_id=1161701 U8955_RS01635 WP_038804175.1 290483..291739(+) (cinA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLMSLLEIASSRSNLVILTGGLGPTEDDLTKQT
LAKFLGKNLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGAKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKAVSQEKANQALDILENQI
LDRQTFEGISLRNICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
EIAEQELKEHGVVSEFTARKMAEQARLKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
QIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1161701 U8955_RS01635 WP_038804175.1 290483..291739(+) (cinA) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGAAAGCAGAAATCATTGCTGTAGGAACGGAAATTTTAACAGGGCAGATCGTCAATACCAACGCCCAGTTTTTATCAGA
AAAGCTAGCAGAAATTGGAGTAGATGTCTACTTCCAAACAGCTGTCGGAGATAATGAAGCGCGTCTCATGTCCTTGCTAG
AGATTGCGAGCTCGCGTAGCAATCTTGTGATTTTGACAGGTGGCTTGGGACCAACCGAGGATGATTTGACCAAACAAACT
CTGGCTAAATTTTTGGGAAAAAATCTAGTGTTTGACCCTCAAGCGCAAGAGAAATTAGATATCTTTTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGGGTGTTGGAAGTGGATGGTGTGACCTACGTGGTTCTCCCAGGACCTCCTAGTGAGTTGAAACCTATG
GTCTTAAATCAACTCTTACCTAAGTTAATGACTGGTGCCAAGTTGTACTCACGAGTGCTCCGTTTCTTTGGGATTGGTGA
AAGTCAGTTGGTGACCATTTTAGCGGATTTGATTGATAATCAAACCGACCCGACCTTGGCTCCGTATGCCAAAACGGGAG
AGGTGACCTTGCGCTTGTCTACAAAAGCAGTCAGTCAAGAAAAGGCCAATCAAGCATTGGACATCTTGGAAAATCAAATC
TTAGATCGCCAGACTTTCGAGGGAATTTCTCTACGAAACATCTGTTATGGATATGGGGAAGAAACCAGCCTAGCAAGTGT
CGTTGTAGAAGAACTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACAGCAGGCCTCTTTCAAGCGACAT
TAGCAGACTTTTCAGGTGTTTCAGCTATCTTTAATGGTGGTTTTGTCACTTACAGTCTAGAAGAAAAGTCCAAGATGCTG
GAAATTGCCGAGCAAGAGCTAAAAGAGCACGGGGTCGTTTCTGAGTTTACAGCTCGAAAAATGGCAGAGCAGGCACGGCT
CAAGACTCAGTCTGATTATGGAGTCAGTTTGACAGGTGTGGCAGGGCCAGATAGCCTAGAGGGTCATCCAGCTGGGACGG
TCTTTATTGGCTTGGCACATGCAAAAGGGACAGAGGTTATCAAGGCCAATATCGCAGGAAGAAGTCGAGCAGATGTTCGT
CAGATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZXR8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.713

100

0.897
  cinA Streptococcus pneumoniae TIGR4

89.474

100

0.895
  cinA Streptococcus pneumoniae Rx1

89.474

100

0.895
  cinA Streptococcus pneumoniae R6

89.474

100

0.895
  cinA Streptococcus pneumoniae D39

89.234

100

0.892
  cinA Streptococcus mitis NCTC 12261

88.756

100

0.888
  cinA Streptococcus mutans UA159

70.096

100

0.701
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment