Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   U8955_RS01400 Genome accession   NZ_OY769914
Coordinates   247041..248057 (+) Length   338 a.a.
NCBI ID   WP_068981894.1    Uniprot ID   -
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 242041..253057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS01380 (SDENT7746_01400) - 242459..244276 (+) 1818 WP_038804055.1 acyltransferase family protein -
  U8955_RS01385 (SDENT7746_01405) nagA 244417..245568 (+) 1152 WP_038804054.1 N-acetylglucosamine-6-phosphate deacetylase -
  U8955_RS01390 (SDENT7746_01410) - 245717..246082 (+) 366 WP_000286399.1 DUF1033 family protein -
  U8955_RS01395 (SDENT7746_01415) comGA/cglA/cilD 246152..247093 (+) 942 WP_038804053.1 competence type IV pilus ATPase ComGA Machinery gene
  U8955_RS01400 (SDENT7746_01420) comGB/cglB 247041..248057 (+) 1017 WP_068981894.1 competence type IV pilus assembly protein ComGB Machinery gene
  U8955_RS01405 (SDENT7746_01425) comGC/cglC 248059..248382 (+) 324 WP_038804052.1 competence type IV pilus major pilin ComGC Machinery gene
  U8955_RS01410 (SDENT7746_01430) comGD/cglD 248345..248779 (+) 435 WP_038804051.1 competence type IV pilus minor pilin ComGD Machinery gene
  U8955_RS01415 (SDENT7746_01435) comGE/cglE 248742..249044 (+) 303 WP_265101009.1 competence type IV pilus minor pilin ComGE Machinery gene
  U8955_RS01420 (SDENT7746_01440) comGF/cglF 249007..249468 (+) 462 WP_038804049.1 competence type IV pilus minor pilin ComGF Machinery gene
  U8955_RS01425 (SDENT7746_01445) comGG 249446..249858 (+) 413 Protein_260 competence type IV pilus minor pilin ComGG -
  U8955_RS01430 (SDENT7746_01450) - 249891..250481 (+) 591 WP_038804047.1 class I SAM-dependent methyltransferase -
  U8955_RS01435 (SDENT7746_01455) comYH 250540..251493 (+) 954 WP_038804046.1 class I SAM-dependent methyltransferase Machinery gene
  U8955_RS01440 (SDENT7746_01460) - 251543..252733 (+) 1191 WP_038804045.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38555.71 Da        Isoelectric Point: 9.7714

>NTDB_id=1161692 U8955_RS01400 WP_068981894.1 247041..248057(+) (comGB/cglB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVTQMHQGLSQGKSFSEMMDSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRGSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAKALQNGREFSQTIARYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=1161692 U8955_RS01400 WP_068981894.1 247041..248057(+) (comGB/cglB) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAATCTCTTCTCCAGTGGTTTTCATTTGGTGGAAATTATTTCTTTCTTGGGGAGAAGTGCCTTGCTAGAAAAGGACTATG
TGACACAGATGCACCAAGGGCTGTCTCAGGGGAAATCCTTTTCAGAGATGATGGACAGCTTGGGTTTTTCAAGTGCTATT
GTGACCCAATTATCTCTAGCTGAAGTTCATGGGAATCTTCATCTGAGTTTGGGAAAGATAGAAGAATATTTGGATAATTT
GGCCAAGGTTAAGAAAAAGTTAATCGAAGTGGCGACCTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GATTGAGAAACTATCTACTACCCCAACTGGACAGTAGCAATATTGCCACCCAAATCATCGGCAATCTGCCACAAATTTTT
CTGGGACTAGTGCTGGTTTGCTCTCTATCTTTACTTTTAGCTCTCACTTTCTACAAAAGAGGTTCTAAGATGCGGGTCTT
CTCGATGTTAGCACGGATTCCCTTTCTTGGAATATTTGTCCAGACCTATCTGACAGCTTATTATGCGCGTGAATGGGGAA
ATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTAAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGAGATATCCATTCTTTAAGAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTAGGGAGTGAGTTGGAAATCTACGCAGAAAAGACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACTATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

93.491

100

0.935
  comGB/cglB Streptococcus mitis NCTC 12261

93.491

100

0.935
  comGB/cglB Streptococcus pneumoniae Rx1

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae D39

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae R6

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae TIGR4

90.828

100

0.908
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

59.561

94.379

0.562
  comYB Streptococcus mutans UA159

59.561

94.379

0.562
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

100

0.521

Multiple sequence alignment