Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   U8955_RS01435 Genome accession   NZ_OY769914
Coordinates   250540..251493 (+) Length   317 a.a.
NCBI ID   WP_038804046.1    Uniprot ID   A0A7T3DZZ0
Organism   Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 245540..256493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U8955_RS01390 (SDENT7746_01410) - 245717..246082 (+) 366 WP_000286399.1 DUF1033 family protein -
  U8955_RS01395 (SDENT7746_01415) comGA/cglA/cilD 246152..247093 (+) 942 WP_038804053.1 competence type IV pilus ATPase ComGA Machinery gene
  U8955_RS01400 (SDENT7746_01420) comGB/cglB 247041..248057 (+) 1017 WP_068981894.1 competence type IV pilus assembly protein ComGB Machinery gene
  U8955_RS01405 (SDENT7746_01425) comGC/cglC 248059..248382 (+) 324 WP_038804052.1 competence type IV pilus major pilin ComGC Machinery gene
  U8955_RS01410 (SDENT7746_01430) comGD/cglD 248345..248779 (+) 435 WP_038804051.1 competence type IV pilus minor pilin ComGD Machinery gene
  U8955_RS01415 (SDENT7746_01435) comGE/cglE 248742..249044 (+) 303 WP_265101009.1 competence type IV pilus minor pilin ComGE Machinery gene
  U8955_RS01420 (SDENT7746_01440) comGF/cglF 249007..249468 (+) 462 WP_038804049.1 competence type IV pilus minor pilin ComGF Machinery gene
  U8955_RS01425 (SDENT7746_01445) comGG 249446..249858 (+) 413 Protein_260 competence type IV pilus minor pilin ComGG -
  U8955_RS01430 (SDENT7746_01450) - 249891..250481 (+) 591 WP_038804047.1 class I SAM-dependent methyltransferase -
  U8955_RS01435 (SDENT7746_01455) comYH 250540..251493 (+) 954 WP_038804046.1 class I SAM-dependent methyltransferase Machinery gene
  U8955_RS01440 (SDENT7746_01460) - 251543..252733 (+) 1191 WP_038804045.1 acetate kinase -
  U8955_RS01445 (SDENT7746_01465) rnpA 252893..253264 (+) 372 WP_000748124.1 ribonuclease P protein component -
  U8955_RS01450 (SDENT7746_01470) - 253239..254051 (+) 813 WP_038804043.1 YidC/Oxa1 family membrane protein insertase -
  U8955_RS01455 (SDENT7746_01475) jag 254069..255058 (+) 990 WP_038804042.1 RNA-binding cell elongation regulator Jag/EloR -
  U8955_RS01460 (SDENT7746_01480) - 255110..255733 (+) 624 WP_038804041.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35583.87 Da        Isoelectric Point: 4.3184

>NTDB_id=1161697 U8955_RS01435 WP_038804046.1 250540..251493(+) (comYH) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQM
EPLQANHQFTPDAIALLLVLIVEELLHKEEISILEIGSGMGILGATFLISLAKKVDYLGIEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAIASRYQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKDEVSLAAIIALPEDIFSTASQAKSIFVLQKKRDKEIEPFVYPLTSLQDPAALLKFKENFQKWSKGTEM

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1161697 U8955_RS01435 WP_038804046.1 250540..251493(+) (comYH) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGGATTTTGAAAAAATTGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTAGAGCAAAATAGTATCTACCTAGATGGTGAGACCGAATTAGAGCAGGTCAAGGAGAACAATC
AAGCTCTTAAACGCTTAGCGCTTCGCAAGGAAGAGTGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCAGGACAAATG
GAGCCTTTGCAGGCCAATCACCAGTTTACGCCGGATGCCATTGCCCTCCTCTTGGTACTTATTGTGGAAGAGTTGCTTCA
TAAAGAGGAAATTAGCATCCTCGAAATAGGTTCTGGAATGGGAATTCTGGGTGCTACTTTCTTGATATCTCTTGCTAAAA
AAGTAGATTACTTGGGAATTGAAGTGGATGATTTGCTGATTGATTTGGCGGCTAGTATGGCAGATGTGATCGGTTTGCAG
GCAGGATTTGTCCAAGGTGATGCCGTTCGTCCGCAAATGCTTAAAGAAAGCGATGTGGTCATTAGCGACTTGCCTGTTGG
CTATTACCCAGACGATGCCATCGCTTCACGCTATCAAGTGGCTTCTAGCCAAGAACATACCTATGCCCATCATTTGCTGA
TGGAGCAAGGCCTCAAGTACCTCAAGTCAGATGGCTATGCTATTTTTCTAGCTCCGAGCGACTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGGTTGGCTCAAAGACGAAGTGAGTCTGGCTGCTATCATCGCTCTGCCAGAGGATATTTTCTCAAC
TGCAAGCCAAGCTAAAAGTATTTTTGTCTTACAGAAGAAAAGAGACAAGGAAATAGAACCATTTGTCTATCCTTTGACCA
GTCTGCAAGATCCAGCTGCACTATTGAAATTCAAAGAAAATTTTCAAAAATGGAGCAAAGGTACTGAAATGTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DZZ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

58.521

98.107

0.574
  comYH Streptococcus mutans UA159

58.199

98.107

0.571

Multiple sequence alignment