Detailed information NTG1161696

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: U8955_RS01420
• Genome accession: NZ_OY769914
• Coordinates: 249007..249468 (+)
• Length: 153 a.a.
• NCBI ID: WP_038804049.1
• Uniprot ID: -
• Organism: Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 244007..254468

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U8955_RS01385 (SDENT7746_01405)	nagA	244417..245568 (+)	1152	WP_038804054.1	N-acetylglucosamine-6-phosphate deacetylase	-
U8955_RS01390 (SDENT7746_01410)	-	245717..246082 (+)	366	WP_000286399.1	DUF1033 family protein	-
U8955_RS01395 (SDENT7746_01415)	comGA/cglA/cilD	246152..247093 (+)	942	WP_038804053.1	competence type IV pilus ATPase ComGA	Machinery gene
U8955_RS01400 (SDENT7746_01420)	comGB/cglB	247041..248057 (+)	1017	WP_068981894.1	competence type IV pilus assembly protein ComGB	Machinery gene
U8955_RS01405 (SDENT7746_01425)	comGC/cglC	248059..248382 (+)	324	WP_038804052.1	competence type IV pilus major pilin ComGC	Machinery gene
U8955_RS01410 (SDENT7746_01430)	comGD/cglD	248345..248779 (+)	435	WP_038804051.1	competence type IV pilus minor pilin ComGD	Machinery gene
U8955_RS01415 (SDENT7746_01435)	comGE/cglE	248742..249044 (+)	303	WP_265101009.1	competence type IV pilus minor pilin ComGE	Machinery gene
U8955_RS01420 (SDENT7746_01440)	comGF/cglF	249007..249468 (+)	462	WP_038804049.1	competence type IV pilus minor pilin ComGF	Machinery gene
U8955_RS01425 (SDENT7746_01445)	comGG	249446..249858 (+)	413	Protein_260	competence type IV pilus minor pilin ComGG	-
U8955_RS01430 (SDENT7746_01450)	-	249891..250481 (+)	591	WP_038804047.1	class I SAM-dependent methyltransferase	-
U8955_RS01435 (SDENT7746_01455)	comYH	250540..251493 (+)	954	WP_038804046.1	class I SAM-dependent methyltransferase	Machinery gene
U8955_RS01440 (SDENT7746_01460)	-	251543..252733 (+)	1191	WP_038804045.1	acetate kinase	-
U8955_RS01445 (SDENT7746_01465)	rnpA	252893..253264 (+)	372	WP_000748124.1	ribonuclease P protein component	-
U8955_RS01450 (SDENT7746_01470)	-	253239..254051 (+)	813	WP_038804043.1	YidC/Oxa1 family membrane protein insertase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17858.57 Da
• Isoelectric Point: 9.5951

>NTDB_id=1161696 U8955_RS01420 WP_038804049.1 249007..249468(+) (comGF/cglF) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
MVQNSCWLSKSHKIKAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQKQSEQKEWLLFVDQLEAELERSQFEKVEGN
RIYMKQDGKDIAMGKSKSDDFRKTDSSGRGYQPMVYGLKSAQITEENQLVRFRFQFQKGLEREFIYRVEKSKS

Nucleotide

• Length: 462 bp

>NTDB_id=1161696 U8955_RS01420 WP_038804049.1 249007..249468(+) (comGF/cglF) [Streptococcus oralis subsp. dentisani isolate Streptococcus dentisani 7746]
ATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAAGATCAAGGCTTTTACCTTGTTGGAATCTCTGATTGCCCTTAT
CGTCATTAGTGGAGGCTTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGTTACCAGAAGCAAAGCG
AGCAAAAAGAGTGGCTCTTGTTTGTGGATCAACTGGAGGCAGAGTTAGAGCGTTCGCAGTTTGAAAAGGTGGAAGGCAAT
CGCATCTACATGAAACAGGATGGTAAGGATATCGCTATGGGTAAGTCTAAATCGGATGATTTTCGGAAGACTGATAGCAG
TGGCCGGGGCTATCAGCCTATGGTTTATGGACTTAAATCCGCTCAGATTACAGAGGAAAATCAATTGGTTCGCTTTCGTT
TCCAATTTCAAAAAGGCTTAGAAAGAGAGTTTATCTATCGTGTTGAAAAATCAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus pneumoniae Rx1	89.542	100	0.895
comGF/cglF	Streptococcus pneumoniae D39	89.542	100	0.895
comGF/cglF	Streptococcus pneumoniae R6	89.542	100	0.895
comGF/cglF	Streptococcus pneumoniae TIGR4	89.542	100	0.895