Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   QOR45_RS09735 Genome accession   NZ_OX460935
Coordinates   1946016..1946594 (-) Length   192 a.a.
NCBI ID   WP_283572268.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate MRI Z2-286     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1946656..1952056 1946016..1946594 flank 62


Gene organization within MGE regions


Location: 1946016..1952056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR45_RS09735 comE/blpR 1946016..1946594 (-) 579 WP_283572268.1 LytTR family DNA-binding domain-containing protein Regulator
  QOR45_RS09740 - 1946656..1947831 (+) 1176 WP_000191687.1 IS256-like element ISSag11 family transposase -
  QOR45_RS09745 - 1947876..1948088 (-) 213 Protein_1851 DNA-binding response regulator -
  QOR45_RS09750 - 1948365..1949180 (-) 816 WP_001029865.1 endonuclease/exonuclease/phosphatase family protein -
  QOR45_RS09755 - 1949234..1950877 (-) 1644 Protein_1853 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 192 a.a.        Molecular weight: 22743.15 Da        Isoelectric Point: 8.2382

>NTDB_id=1159002 QOR45_RS09735 WP_283572268.1 1946016..1946594(-) (comE/blpR) [Streptococcus agalactiae isolate MRI Z2-286]
MFTQDILHYLGLEVAKQIRQVDPYAQIVFVTTHSELMPLTFRYQVSALDNIDKGLSQEEFSQRIEEVLLYVDGICNKPLV
ENSFYFKSRYSQVQLPFNDLLYIETSSRSHRVVLYTEKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRL
VYFQNGTTCLISRNKVRDIVSIVDKYQKDRKR

Nucleotide


Download         Length: 579 bp        

>NTDB_id=1159002 QOR45_RS09735 WP_283572268.1 1946016..1946594(-) (comE/blpR) [Streptococcus agalactiae isolate MRI Z2-286]
GTGTTTACACAAGATATTTTACACTACCTAGGCTTAGAGGTCGCAAAACAAATTAGACAAGTTGATCCTTATGCTCAGAT
TGTTTTTGTTACAACTCATTCAGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGACAATATCGATAAAG
GACTTTCACAGGAAGAGTTTAGCCAAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCAATAAGCCCTTAGTG
GAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATCTTCTTTATATAGAAACATCCTC
AAGATCACATAGAGTTGTCCTTTATACTGAAAAAGATAGAATGGAATTCACAGCCACTTTGGGGGATATTTTAAAACAAG
AACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTAAATATTTTTAAAGTGGATAGGATAGATAGATTA
GTTTACTTCCAAAATGGAACGACTTGTCTGATTTCACGCAATAAAGTGAGAGATATAGTATCTATAGTGGATAAATATCA
AAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(93-180)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

55.172

90.625

0.5
  comE Streptococcus infantis strain Atu-4

40.541

96.354

0.391
  comE/comE1 Streptococcus equinus JB1

42.857

91.146

0.391
  comE Streptococcus pneumoniae TIGR4

39.56

94.792

0.375
  comE Streptococcus mitis SK321

39.56

94.792

0.375
  comE Streptococcus mitis NCTC 12261

39.56

94.792

0.375
  comE Streptococcus pneumoniae R6

39.56

94.792

0.375
  comE Streptococcus pneumoniae Rx1

39.56

94.792

0.375
  comE Streptococcus pneumoniae D39

39.56

94.792

0.375
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.458

100

0.365
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.458

100

0.365

Multiple sequence alignment