Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   QOR44_RS01115 Genome accession   NZ_OX460931
Coordinates   190099..190428 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae isolate MRI Z2-174     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 185099..195428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR44_RS01100 - 187657..188022 (+) 366 WP_000285373.1 DUF1033 family protein -
  QOR44_RS01105 comYA 188194..189165 (+) 972 WP_283572657.1 competence type IV pilus ATPase ComGA Machinery gene
  QOR44_RS01110 comYB 189059..190102 (+) 1044 WP_228322108.1 competence type IV pilus assembly protein ComGB Machinery gene
  QOR44_RS01115 comGC/cglC 190099..190428 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  QOR44_RS01120 comYD 190403..190816 (+) 414 WP_017646959.1 competence type IV pilus minor pilin ComGD Machinery gene
  QOR44_RS01125 comGE 190842..191087 (+) 246 WP_283572658.1 competence type IV pilus minor pilin ComGE -
  QOR44_RS01130 comGF 191041..191502 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  QOR44_RS01135 comGG 191480..191851 (+) 372 WP_000601103.1 competence type IV pilus minor pilin ComGG -
  QOR44_RS01140 comYH 191966..192940 (+) 975 WP_001008568.1 class I SAM-dependent methyltransferase Machinery gene
  QOR44_RS01145 - 192972..194165 (+) 1194 WP_000047537.1 acetate kinase -
  QOR44_RS01150 - 194317..194523 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  QOR44_RS01155 - 194582..194719 (+) 138 WP_079263416.1 hypothetical protein -
  QOR44_RS01160 - 194822..195214 (+) 393 WP_001265365.1 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=1158859 QOR44_RS01115 WP_000793380.1 190099..190428(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-174]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=1158859 QOR44_RS01115 WP_000793380.1 190099..190428(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-174]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment