Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SMUFR_RS09620 Genome accession   NZ_CP007016
Coordinates   1956301..1957557 (-) Length   418 a.a.
NCBI ID   WP_002262393.1    Uniprot ID   Q8DRX2
Organism   Streptococcus mutans UA159-FR     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1951301..1962557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUFR_RS09580 (SMUFR_1802) - 1951495..1951794 (-) 300 WP_002262384.1 DUF1292 domain-containing protein -
  SMUFR_RS09585 (SMUFR_1803) ruvX 1951875..1952294 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  SMUFR_RS09590 (SMUFR_1804) - 1952291..1952560 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  SMUFR_RS09595 (SMUFR_1805) brsR 1952728..1953162 (+) 435 WP_002262387.1 bacteriocin genes transcriptional regulator BrsR Regulator
  SMUFR_RS09600 (SMUFR_1806) brsM 1953175..1953621 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  SMUFR_RS10575 - 1953612..1953824 (-) 213 WP_002262389.1 hypothetical protein -
  SMUFR_RS09605 (SMUFR_1807) - 1953951..1954376 (-) 426 WP_002262390.1 hypothetical protein -
  SMUFR_RS09610 (SMUFR_1808) spx 1954627..1955025 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  SMUFR_RS09615 (SMUFR_1809) recA 1955110..1956261 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  SMUFR_RS09620 (SMUFR_1810) cinA 1956301..1957557 (-) 1257 WP_002262393.1 competence/damage-inducible protein A Machinery gene
  SMUFR_RS09625 (SMUFR_1811) - 1957706..1958266 (-) 561 WP_002262394.1 DNA-3-methyladenine glycosylase I -
  SMUFR_RS09630 (SMUFR_1812) ruvA 1958348..1958941 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  SMUFR_RS09635 (SMUFR_1813) mutL 1959124..1961079 (-) 1956 WP_002262396.1 DNA mismatch repair endonuclease MutL -
  SMUFR_RS10580 - 1961304..1961582 (+) 279 Protein_1857 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45732.54 Da        Isoelectric Point: 6.2714

>NTDB_id=115811 SMUFR_RS09620 WP_002262393.1 1956301..1957557(-) (cinA) [Streptococcus mutans UA159-FR]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKAHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAISLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=115811 SMUFR_RS09620 WP_002262393.1 1956301..1957557(-) (cinA) [Streptococcus mutans UA159-FR]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGTGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACACCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGTT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGCCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTATTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 6MR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

100

100

1
  cinA Streptococcus mitis SK321

72.488

100

0.725
  cinA Streptococcus mitis NCTC 12261

71.77

100

0.718
  cinA Streptococcus pneumoniae TIGR4

70.813

100

0.708
  cinA Streptococcus pneumoniae Rx1

70.574

100

0.706
  cinA Streptococcus pneumoniae R6

70.574

100

0.706
  cinA Streptococcus pneumoniae D39

70.335

100

0.703
  cinA Streptococcus suis isolate S10

55.474

98.325

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.005

98.804

0.455

Multiple sequence alignment