Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AD178_RS09345 Genome accession   NZ_OX244288
Coordinates   1814727..1815983 (-) Length   418 a.a.
NCBI ID   WP_000642706.1    Uniprot ID   A0A098Z3K2
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1809727..1820983
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS09330 (SAMEA1463109_01883) lytA 1810498..1811454 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  AD178_RS09335 (SAMEA1463109_01884) - 1811830..1813200 (-) 1371 WP_001036241.1 MATE family efflux transporter -
  AD178_RS09340 (SAMEA1463109_01885) recA 1813506..1814672 (-) 1167 WP_001085464.1 recombinase RecA Machinery gene
  AD178_RS09345 (SAMEA1463109_01886) cinA 1814727..1815983 (-) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  AD178_RS09350 (SAMEA1463109_01887) - 1816068..1817084 (-) 1017 WP_000239282.1 LCP family protein -
  AD178_RS09355 (SAMEA1463109_01888) - 1817092..1817610 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  AD178_RS09360 (SAMEA1463109_01889) tsaE 1817600..1818043 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  AD178_RS09365 (SAMEA1463109_01890) comM 1818129..1818749 (-) 621 WP_000839908.1 hypothetical protein Regulator
  AD178_RS09370 (SAMEA1463109_01891) - 1819132..1819995 (-) 864 WP_001093641.1 helix-turn-helix transcriptional regulator -
  AD178_RS09375 (SAMEA1463109_01892) - 1820187..1820357 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  AD178_RS09380 (SAMEA1463109_01893) pneA1 1820460..1820684 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  AD178_RS09385 (SAMEA1463109_01894) pneA2 1820691..1820879 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45062.40 Da        Isoelectric Point: 4.5211

>NTDB_id=1154347 AD178_RS09345 WP_000642706.1 1814727..1815983(-) (cinA) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1154347 AD178_RS09345 WP_000642706.1 1814727..1815983(-) (cinA) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTGAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z3K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae Rx1

99.761

100

0.998
  cinA Streptococcus pneumoniae R6

99.761

100

0.998
  cinA Streptococcus pneumoniae TIGR4

99.522

100

0.995
  cinA Streptococcus pneumoniae D39

99.522

100

0.995
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment