Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   AD178_RS09365 Genome accession   NZ_OX244288
Coordinates   1818129..1818749 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1813129..1823749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS09340 (SAMEA1463109_01885) recA 1813506..1814672 (-) 1167 WP_001085464.1 recombinase RecA Machinery gene
  AD178_RS09345 (SAMEA1463109_01886) cinA 1814727..1815983 (-) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  AD178_RS09350 (SAMEA1463109_01887) - 1816068..1817084 (-) 1017 WP_000239282.1 LCP family protein -
  AD178_RS09355 (SAMEA1463109_01888) - 1817092..1817610 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  AD178_RS09360 (SAMEA1463109_01889) tsaE 1817600..1818043 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  AD178_RS09365 (SAMEA1463109_01890) comM 1818129..1818749 (-) 621 WP_000839908.1 hypothetical protein Regulator
  AD178_RS09370 (SAMEA1463109_01891) - 1819132..1819995 (-) 864 WP_001093641.1 helix-turn-helix transcriptional regulator -
  AD178_RS09375 (SAMEA1463109_01892) - 1820187..1820357 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  AD178_RS09380 (SAMEA1463109_01893) pneA1 1820460..1820684 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  AD178_RS09385 (SAMEA1463109_01894) pneA2 1820691..1820879 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=1154348 AD178_RS09365 WP_000839908.1 1818129..1818749(-) (comM) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1154348 AD178_RS09365 WP_000839908.1 1818129..1818749(-) (comM) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTGGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment