Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   OC536_RS02520 Genome accession   NZ_OW443150
Coordinates   532827..534053 (-) Length   408 a.a.
NCBI ID   WP_032476648.1    Uniprot ID   -
Organism   Vibrio cholerae strain CNRVC190247 isolate YE-NCPHL-18035-PI     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 527827..539053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OC536_RS02500 (CNRVC190247_00507) yacG 530162..530359 (-) 198 WP_032476646.1 DNA gyrase inhibitor YacG -
  OC536_RS02505 (CNRVC190247_00508) zapD 530517..531257 (-) 741 WP_000207194.1 cell division protein ZapD -
  OC536_RS02510 (CNRVC190247_00509) coaE 531289..531897 (-) 609 WP_000011550.1 dephospho-CoA kinase -
  OC536_RS02515 (CNRVC190247_00510) pilD 531894..532769 (-) 876 WP_032476647.1 A24 family peptidase Machinery gene
  OC536_RS02520 (CNRVC190247_00511) pilC 532827..534053 (-) 1227 WP_032476648.1 type II secretion system F family protein Machinery gene
  OC536_RS02525 (CNRVC190247_00512) pilB 534096..535784 (-) 1689 WP_032476649.1 type IV-A pilus assembly ATPase PilB Machinery gene
  OC536_RS02530 (CNRVC190247_00513) - 535791..536201 (-) 411 WP_032476650.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  OC536_RS02535 (CNRVC190247_00514) nadC 536447..537337 (-) 891 WP_000665277.1 carboxylating nicotinate-nucleotide diphosphorylase -
  OC536_RS02540 (CNRVC190247_00515) ampD 537639..538184 (+) 546 WP_000567319.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  OC536_RS02545 (CNRVC190247_00516) fldB 538335..538853 (-) 519 WP_000690112.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45048.38 Da        Isoelectric Point: 10.3424

>NTDB_id=1152337 OC536_RS02520 WP_032476648.1 532827..534053(-) (pilC) [Vibrio cholerae strain CNRVC190247 isolate YE-NCPHL-18035-PI]
MKATQTLPLKNYRWKGISSNGKKVSGQMLAISEIEVRDKLKDQHIQIKKLKKGSVSLVARLTHRVKGKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVLAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFETAINEVYRDTAA
GMPMYIAMRNTEAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1152337 OC536_RS02520 WP_032476648.1 532827..534053(-) (pilC) [Vibrio cholerae strain CNRVC190247 isolate YE-NCPHL-18035-PI]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAGCAGCAACGGCAAAAAAGTTTCCGGCCA
GATGCTCGCCATCTCCGAAATCGAGGTGCGCGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTCAAAAAAGGCA
GTGTCTCTTTAGTGGCGCGCCTAACCCATCGCGTGAAAGGCAAAGACATCACGATTTTGACTCGGCAGTTGGCGACCATG
CTCACCACGGGCGTACCCATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATTACCAAAAGCGTGGAAGCGGGCACGCCGCTTTCCAAGGCGATGCGCACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGACTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAAGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAGCAACTACGCGCCAAGGTGATTAAAGCGCTCATCTACCCCAGCATGGTGGTGTTGGTCGCGCTCGGGGTATC
TTACTTAATGCTCACCATGGTCATCCCAGAATTTGAAAGCATGTTTAAAGGCTTTGGTGCTGAACTGCCTTGGTTTACCC
AGCAAGTACTGAAACTCTCACACTGGGTGCTGGCTTACAGTTTATGGGCATTTATCGCCATCGCAGCAGCCATTTTTGGC
TTGAAAGCGCTGCGTAAAAACTCTTTCCAGATCCGTTTAAAAACCAGCCGCTTGGGGCTGAAATTTCCGATTATTGGCAA
TGTACTCGCCAAAGCGTCCATCGCCAAATTCAGCCGCACCCTCGCCACCAGCTTTGCCGCGGGGATCCCGATCCTCGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAACCGCGATTAATGAGGTGTACCGCGATACCGCTGCG
GGTATGCCGATGTACATTGCCATGCGCAATACCGAAGCTTTTCCCGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCAGGGCAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACGGTCGATAACTTGG
GCAAGATTCTTGAACCACTGATCATCGTCTTTCTTGGGACGGTTGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.02

100

0.99
  pilC Vibrio campbellii strain DS40M4

73.5

98.039

0.721
  pilC Acinetobacter baumannii D1279779

42.157

100

0.422
  pilC Acinetobacter baylyi ADP1

41.769

99.755

0.417
  pilC Pseudomonas stutzeri DSM 10701

42.105

97.794

0.412
  pilC Legionella pneumophila strain ERS1305867

41.709

97.549

0.407
  pilG Neisseria gonorrhoeae MS11

41.73

96.324

0.402
  pilG Neisseria meningitidis 44/76-A

41.221

96.324

0.397

Multiple sequence alignment