Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   N7O26_RS12045 Genome accession   NZ_OV996158
Coordinates   2643182..2644426 (-) Length   414 a.a.
NCBI ID   WP_071866531.1    Uniprot ID   A0A1L8V0I3
Organism   Enterococcus mundtii strain P2005     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2638182..2649426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N7O26_RS12030 - 2639803..2639997 (-) 195 WP_130029219.1 hypothetical protein -
  N7O26_RS12035 rny 2640191..2641747 (-) 1557 WP_071866532.1 ribonuclease Y -
  N7O26_RS12040 recA 2642036..2643076 (-) 1041 WP_010734076.1 recombinase RecA Machinery gene
  N7O26_RS12045 cinA 2643182..2644426 (-) 1245 WP_071866531.1 competence/damage-inducible protein A Machinery gene
  N7O26_RS12050 pgsA 2644653..2645231 (-) 579 WP_019723896.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N7O26_RS12055 - 2645403..2646293 (-) 891 WP_260697829.1 RodZ family helix-turn-helix domain-containing protein -
  N7O26_RS12060 yfmH 2646588..2647877 (-) 1290 WP_086335491.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  N7O26_RS12065 yfmF 2647870..2649138 (-) 1269 WP_260697830.1 EF-P 5-aminopentanol modification-associated protein YfmF -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45163.60 Da        Isoelectric Point: 5.0822

>NTDB_id=1152181 N7O26_RS12045 WP_071866531.1 2643182..2644426(-) (cinA) [Enterococcus mundtii strain P2005]
MKSEIIAVGTELLLGQVVNTNATFLSEQLADLGIDVYYHTVVGDNPTRLEELLQLAESRSELIILCGGLGPTEDDLTKEV
VAQHLGKELIQNTEGYKKLLAFFETTKRKMTENNLQQSQIIEGGTPLPNRTGLALGTFYQTKSNAYLLLPGPPSELKPMF
VEQVRPLLEQQFPSEEKLISKVLRFYGIGESQLVTDLKDLIATQINPTIAPYAKPNEVTLRLTVKTSDIHAGNQALHALE
EKIQARVGAYFYGYGDDYSLPQAVVDLLKEQGKTVTAAESLTAGGFQSALGAIPGVSQVFSGGFVTYSAETKAKLLGIDP
ELLEQFGTVSKECAEQMAIRARQLVGTDYAVAFTGVAGPDTLEGHPAGTVWLAVASKEGVETKECHFTRDRSAIRNSAIM
QGFDLLRKQLLRKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=1152181 N7O26_RS12045 WP_071866531.1 2643182..2644426(-) (cinA) [Enterococcus mundtii strain P2005]
ATGAAATCTGAAATCATAGCAGTAGGAACAGAATTATTACTTGGACAAGTCGTGAATACGAATGCGACATTTTTATCAGA
ACAGTTAGCAGATCTAGGAATCGATGTCTATTATCACACAGTTGTCGGGGATAATCCGACTCGTTTGGAGGAGTTACTCC
AGTTAGCTGAATCGAGAAGTGAACTAATCATTTTATGTGGTGGACTAGGACCAACAGAAGATGACTTAACAAAAGAAGTT
GTCGCTCAACACCTCGGCAAAGAGCTGATCCAAAACACAGAAGGGTACAAGAAACTGCTGGCATTTTTCGAAACGACAAA
AAGAAAAATGACGGAGAACAATTTACAACAATCTCAGATCATTGAAGGGGGCACACCATTACCTAATCGAACTGGCTTAG
CGTTAGGCACGTTTTATCAAACGAAAAGCAATGCTTATCTTTTACTTCCTGGGCCACCAAGTGAGTTGAAGCCGATGTTT
GTAGAACAAGTGCGACCACTGTTAGAACAACAATTCCCTTCAGAAGAAAAACTGATTTCAAAAGTGTTGCGCTTCTATGG
CATCGGTGAATCACAATTAGTAACCGATCTAAAAGACTTGATTGCTACCCAAATCAATCCCACGATTGCTCCTTATGCCA
AACCAAATGAAGTCACACTGAGATTGACAGTCAAAACGTCAGATATCCATGCAGGGAATCAAGCATTGCACGCACTAGAA
GAAAAAATCCAAGCCCGTGTCGGTGCATATTTTTATGGCTATGGGGATGACTATTCGTTGCCACAAGCCGTCGTGGATCT
GCTAAAAGAACAGGGGAAGACAGTCACAGCAGCTGAAAGTTTGACAGCGGGAGGCTTTCAATCCGCGTTAGGAGCAATTC
CTGGCGTCTCTCAAGTCTTTTCTGGGGGCTTTGTGACTTATTCAGCAGAGACCAAAGCAAAGCTCTTAGGCATCGATCCA
GAACTATTAGAGCAGTTTGGCACAGTCAGTAAAGAATGTGCCGAACAAATGGCGATTCGAGCACGCCAACTCGTTGGTAC
AGATTATGCCGTAGCGTTTACCGGTGTGGCGGGACCCGACACATTAGAAGGACATCCTGCGGGTACAGTTTGGCTTGCCG
TTGCATCAAAAGAAGGCGTAGAAACAAAAGAATGTCACTTTACGAGAGACCGTTCGGCAATCAGAAATAGTGCGATTATG
CAAGGATTTGATCTGCTAAGAAAGCAACTATTAAGAAAAAAATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(259-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L8V0I3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.828

100

0.543
  cinA Streptococcus mitis SK321

52.381

100

0.531
  cinA Streptococcus pneumoniae TIGR4

52.381

100

0.531
  cinA Streptococcus pneumoniae Rx1

52.143

100

0.529
  cinA Streptococcus pneumoniae R6

52.143

100

0.529
  cinA Streptococcus pneumoniae D39

52.143

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.905

100

0.527
  cinA Bacillus subtilis subsp. subtilis str. 168

49.029

99.517

0.488
  cinA Streptococcus suis isolate S10

43.478

100

0.435

Multiple sequence alignment