Detailed information NTG1149431

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: DXE60_RS13755
• Genome accession: NZ_LT992461
• Coordinates: 2628751..2629062 (-)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate 8_LA_272
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2623751..2634062

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DXE60_RS13720	gcvPA	2624253..2625599 (-)	1347	WP_031795510.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
DXE60_RS13725	gcvT	2625619..2626710 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
DXE60_RS13730	-	2626869..2627393 (-)	525	WP_001015120.1	shikimate kinase	-
DXE60_RS13735	-	2627383..2627529 (-)	147	WP_001789879.1	hypothetical protein	-
DXE60_RS13740	comGF	2627626..2628123 (-)	498	WP_001825340.1	competence type IV pilus minor pilin ComGF	Machinery gene
DXE60_RS13745	comGE	2628041..2628340 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
DXE60_RS13750	comGD	2628327..2628773 (-)	447	WP_001796473.1	competence type IV pilus minor pilin ComGD	Machinery gene
DXE60_RS13755	comGC	2628751..2629062 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
DXE60_RS13760	comGB	2629076..2630146 (-)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
DXE60_RS13765	comGA	2630118..2631092 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
DXE60_RS13770	-	2631144..2631767 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
DXE60_RS13775	-	2631764..2632093 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
DXE60_RS13780	-	2632093..2633079 (-)	987	WP_000161315.1	ROK family glucokinase	-
DXE60_RS13785	-	2633076..2633279 (-)	204	WP_000087559.1	YqgQ family protein	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=1149431 DXE60_RS13755 WP_000472256.1 2628751..2629062(-) (comGC) [Staphylococcus aureus isolate 8_LA_272]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=1149431 DXE60_RS13755 WP_000472256.1 2628751..2629062(-) (comGC) [Staphylococcus aureus isolate 8_LA_272]
ATGTTTAAATTTCTAAAAAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTATTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comYC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comYC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369