Detailed information NTG1147466

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: CKV85_RS00950
• Genome accession: NZ_LT906454
• Coordinates: 188599..189345 (+)
• Length: 248 a.a.
• NCBI ID: WP_095123684.1
• Uniprot ID: -
• Organism: Streptococcus acidominimus strain NCTC11291
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 183599..194345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV85_RS00935 (SAMEA4504048_00195)	gltX	184448..185902 (+)	1455	WP_017770627.1	glutamate--tRNA ligase	-
CKV85_RS00940 (SAMEA4504048_00196)	-	185988..187295 (+)	1308	WP_095121477.1	hypothetical protein	-
CKV85_RS00945 (SAMEA4504048_00197)	-	187298..188599 (+)	1302	WP_095121479.1	GHKL domain-containing protein	-
CKV85_RS00950 (SAMEA4504048_00198)	comE/blpR	188599..189345 (+)	747	WP_095123684.1	response regulator transcription factor	Regulator
CKV85_RS00955 (SAMEA4504048_00200)	ltrA	190074..191351 (+)	1278	WP_095121481.1	group II intron reverse transcriptase/maturase	-
CKV85_RS00960 (SAMEA4504048_00201)	-	191515..192216 (+)	702	WP_095121483.1	histidine phosphatase family protein	-
CKV85_RS00965 (SAMEA4504048_00202)	-	192206..192973 (+)	768	WP_079268479.1	M15 family metallopeptidase	-
CKV85_RS00970 (SAMEA4504048_00203)	-	193021..193572 (+)	552	WP_231909821.1	glucosaminidase domain-containing protein	-

Sequence

Protein

• Length: 248 a.a.
• Molecular weight: 28844.91 Da
• Isoelectric Point: 7.1733

>NTDB_id=1147466 CKV85_RS00950 WP_095123684.1 188599..189345(+) (comE/blpR) [Streptococcus acidominimus strain NCTC11291]
MNIFILEDNLRQQERLLSTVKAILKEENISARHLAAYSKSSNLLADITERGSHQLFFFDIEIKDEERKGLEIASEVRKLD
PNAIIVFVTTHSEFAPISFKYKVAAYDFIDKSLDADDFKEQVRESIRYTATLSGSAQTDVDYFDYKSAKAQVKVPLHDIL
YFETSQIAHKLILRTRTERLEFYAKISDIEKMHDKFFQCHRSFLVNIDNVSRIDKANQLAYFDNGESCLVSRLKMKALIA
RWKKAFHD

Nucleotide

• Length: 747 bp

>NTDB_id=1147466 CKV85_RS00950 WP_095123684.1 188599..189345(+) (comE/blpR) [Streptococcus acidominimus strain NCTC11291]
ATGAATATTTTTATCTTAGAAGATAACCTTCGACAGCAGGAGCGTCTCTTGTCAACGGTTAAGGCTATATTAAAAGAAGA
AAACATATCAGCAAGGCATTTGGCAGCTTATAGTAAATCAAGTAACTTACTCGCAGATATCACAGAAAGAGGTAGTCACC
AATTATTCTTCTTTGATATTGAAATTAAAGATGAAGAACGCAAGGGCCTTGAAATTGCTTCGGAAGTGCGAAAGCTAGAT
CCTAATGCTATCATTGTTTTTGTGACAACACACTCTGAATTTGCACCGATTAGTTTTAAGTATAAGGTTGCGGCCTATGA
TTTTATTGACAAATCACTAGATGCTGACGATTTTAAAGAACAGGTTCGTGAAAGCATTCGTTATACAGCTACCTTGTCTG
GCAGTGCTCAAACAGATGTTGATTACTTCGACTATAAGTCAGCCAAGGCCCAGGTTAAGGTTCCTCTCCATGATATTTTG
TACTTTGAGACATCTCAAATTGCACATAAACTCATTTTACGAACGCGCACAGAACGCTTGGAATTTTATGCCAAAATATC
TGATATTGAAAAAATGCACGATAAGTTCTTCCAATGCCACCGTTCGTTTTTGGTGAATATCGATAATGTTAGCCGAATTG
ATAAGGCGAACCAGCTGGCTTATTTTGACAATGGTGAGTCCTGTCTGGTATCGCGCTTGAAAATGAAAGCCTTGATTGCA
AGATGGAAAAAAGCATTTCATGATTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (14-122)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.79	100	0.488
comE/comE1	Streptococcus equinus JB1	39.676	99.597	0.395
comE	Streptococcus infantis strain Atu-4	39.004	97.177	0.379
comE	Streptococcus pneumoniae Rx1	39.004	97.177	0.379
comE	Streptococcus pneumoniae D39	39.004	97.177	0.379
comE	Streptococcus pneumoniae R6	39.004	97.177	0.379
comE	Streptococcus pneumoniae TIGR4	39.004	97.177	0.379
comE	Streptococcus mitis SK321	39.004	97.177	0.379
comE	Streptococcus mitis NCTC 12261	39.004	97.177	0.379
comE/comE2	Streptococcus gordonii strain NCTC7865	37.86	97.984	0.371
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	37.86	97.984	0.371