Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CKV83_RS09410 Genome accession   NZ_LT906439
Coordinates   2005533..2006795 (+) Length   420 a.a.
NCBI ID   WP_018374053.1    Uniprot ID   A0A239SYD6
Organism   Streptococcus merionis strain NCTC13788     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2000533..2011795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS11730 - 2000674..2000973 (-) 300 WP_018374060.1 hypothetical protein -
  CKV83_RS11805 - 2000960..2001232 (-) 273 WP_095114574.1 IS630 transposase-related protein -
  CKV83_RS09385 (SAMEA4412692_01872) - 2001595..2001846 (-) 252 WP_018374058.1 hypothetical protein -
  CKV83_RS09390 (SAMEA4412692_01874) - 2002117..2002977 (-) 861 WP_018374057.1 helix-turn-helix domain-containing protein -
  CKV83_RS09395 (SAMEA4412692_01875) - 2003067..2003963 (+) 897 WP_018374056.1 ATP-binding cassette domain-containing protein -
  CKV83_RS09400 (SAMEA4412692_01876) - 2003950..2004645 (+) 696 WP_018374055.1 ABC transporter permease -
  CKV83_RS11630 - 2004787..2005254 (-) 468 Protein_1805 recombinase family protein -
  CKV83_RS11810 - 2005300..2005443 (-) 144 Protein_1806 replication protein RepR -
  CKV83_RS09410 (SAMEA4412692_01877) cinA 2005533..2006795 (+) 1263 WP_018374053.1 competence/damage-inducible protein A Machinery gene
  CKV83_RS09415 (SAMEA4412692_01878) recA 2006843..2007985 (+) 1143 WP_018374052.1 recombinase RecA Machinery gene
  CKV83_RS09420 (SAMEA4412692_01879) spx 2008068..2008466 (+) 399 WP_018374051.1 transcriptional regulator Spx -
  CKV83_RS09425 (SAMEA4412692_01880) treC 2008870..2010504 (-) 1635 WP_018374050.1 alpha,alpha-phosphotrehalase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 45091.31 Da        Isoelectric Point: 4.6536

>NTDB_id=1147150 CKV83_RS09410 WP_018374053.1 2005533..2006795(+) (cinA) [Streptococcus merionis strain NCTC13788]
MKAEVIAVGTEILTGQIVNTNAQFLSEKFAQIGVDVFYHTAVGDNEERLLAALEIARDRSDLIVLCGGLGPTEDDLTKQT
LARFLGRDLVFDEAALARLDSFFASRPASSRTPNNERQAQIVVGSTPLPNQTGLAVGGLLEQNGVTYVVLPGPPSELKPM
VTEELIPLLVSQNQKQQLYSRVLRFFGIGESQLVTVLGDLINQQTDPTIAPYAKTGEVTLRLSTKASSKVEADAKLDKLE
EKILTHGELSQLMYGYGDDNSLAAVVFELLLSQGATLTAAESLTAGLFQATLADFSGASQVFPGGFVTYSLEQKSQMLGI
DPEKLAAAGVVSDFTACAMAEQARKLTSSDYGVSLTGVAGPDRLEDQPVGTVFIGLSSHKETKAYRFMIGGRSRQDVRQI
ACMHAFNLIRQTLLNGGNLL

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=1147150 CKV83_RS09410 WP_018374053.1 2005533..2006795(+) (cinA) [Streptococcus merionis strain NCTC13788]
ATGAAAGCTGAAGTGATTGCAGTGGGAACAGAGATTCTGACTGGTCAGATTGTCAATACTAATGCCCAATTTTTGTCGGA
GAAATTTGCTCAGATCGGGGTGGATGTCTTCTACCATACAGCTGTTGGAGATAATGAAGAGCGGTTGCTGGCAGCGTTAG
AAATAGCTCGTGACAGGAGTGATTTGATTGTTCTCTGTGGGGGTCTTGGGCCGACTGAGGATGATTTGACCAAGCAAACT
TTGGCTCGTTTTCTAGGTCGGGATTTGGTCTTTGATGAGGCTGCTTTAGCGAGATTGGACAGCTTTTTTGCGAGTAGGCC
AGCTAGTTCTCGTACGCCCAATAACGAACGGCAAGCCCAAATCGTGGTCGGAAGTACTCCCTTGCCTAATCAAACGGGTC
TAGCAGTTGGTGGTCTCCTTGAGCAGAACGGAGTGACCTATGTTGTTTTACCTGGGCCTCCTAGTGAGCTCAAGCCTATG
GTGACAGAGGAATTGATTCCTTTACTAGTTAGTCAGAATCAGAAACAGCAGCTTTATTCCCGTGTTTTACGATTCTTTGG
CATTGGTGAAAGCCAATTGGTGACCGTCTTGGGCGATCTAATCAATCAGCAGACGGATCCGACCATTGCTCCATATGCTA
AGACTGGTGAAGTAACCTTGCGCCTGTCTACTAAGGCAAGTTCTAAGGTCGAGGCAGATGCTAAGTTGGATAAATTGGAA
GAGAAAATCTTGACTCATGGTGAACTCTCCCAACTTATGTACGGCTATGGTGATGACAACAGTTTGGCAGCAGTTGTTTT
TGAACTGCTACTGTCTCAAGGGGCAACTCTGACCGCAGCAGAAAGTCTGACAGCAGGACTTTTTCAGGCAACTTTGGCTG
ACTTTTCGGGAGCTTCTCAGGTTTTCCCAGGAGGCTTTGTGACCTACAGTTTGGAGCAAAAATCTCAGATGTTGGGCATT
GATCCTGAGAAGTTGGCAGCAGCTGGTGTGGTGTCTGATTTTACCGCTTGCGCCATGGCAGAGCAGGCTAGAAAATTGAC
CAGCAGTGACTATGGCGTGTCATTAACAGGAGTGGCTGGTCCAGACAGGTTAGAGGATCAGCCAGTAGGCACTGTTTTTA
TAGGCTTGTCCAGTCACAAAGAAACCAAAGCCTACCGCTTCATGATTGGGGGTAGAAGCCGTCAGGATGTCCGCCAAATC
GCCTGCATGCACGCCTTTAATCTCATACGGCAAACTTTATTAAATGGCGGAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(260-413)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239SYD6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.667

100

0.717
  cinA Streptococcus mitis SK321

70

100

0.7
  cinA Streptococcus mitis NCTC 12261

68.571

100

0.686
  cinA Streptococcus pneumoniae TIGR4

68.333

100

0.683
  cinA Streptococcus pneumoniae Rx1

68.333

100

0.683
  cinA Streptococcus pneumoniae R6

68.333

100

0.683
  cinA Streptococcus pneumoniae D39

68.095

100

0.681
  cinA Streptococcus suis isolate S10

56.659

98.333

0.557
  cinA Bacillus subtilis subsp. subtilis str. 168

47.458

98.333

0.467

Multiple sequence alignment