Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BUC38_RS00420 Genome accession   NZ_LT671674
Coordinates   78942..80123 (+) Length   393 a.a.
NCBI ID   WP_044689742.1    Uniprot ID   A0A0Z8IGV6
Organism   Streptococcus suis strain LS9N     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 73942..85123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS00395 mutL 74471..76408 (+) 1938 WP_044689739.1 DNA mismatch repair endonuclease MutL -
  BUC38_RS00400 - 76482..76847 (+) 366 WP_052503050.1 helix-turn-helix transcriptional regulator -
  BUC38_RS00405 - 76862..77509 (+) 648 WP_044672699.1 type II CAAX endopeptidase family protein -
  BUC38_RS00410 ruvA 77587..78177 (+) 591 WP_024406764.1 Holliday junction branch migration protein RuvA -
  BUC38_RS00415 - 78336..78905 (+) 570 WP_044689741.1 DNA-3-methyladenine glycosylase I -
  BUC38_RS00420 cinA 78942..80123 (+) 1182 WP_044689742.1 competence/damage-inducible protein A Machinery gene
  BUC38_RS00425 recA 80175..81326 (+) 1152 WP_004195473.1 recombinase RecA Machinery gene
  BUC38_RS00430 spx 81485..81883 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  BUC38_RS00435 - 81990..82256 (+) 267 WP_004195477.1 IreB family regulatory phosphoprotein -
  BUC38_RS00440 ruvX 82256..82675 (+) 420 WP_044689743.1 Holliday junction resolvase RuvX -
  BUC38_RS00445 - 82687..83004 (+) 318 WP_004195480.1 DUF1292 domain-containing protein -
  BUC38_RS00450 - 83314..83859 (+) 546 Protein_68 nucleotidyltransferase family protein -
  BUC38_RS00455 comX/sigX 83961..84431 (+) 471 WP_044689744.1 sigma-70 family RNA polymerase sigma factor Regulator
  BUC38_RS00465 rpsJ 84697..85005 (+) 309 WP_002939332.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42884.74 Da        Isoelectric Point: 4.3747

>NTDB_id=1145966 BUC38_RS00420 WP_044689742.1 78942..80123(+) (cinA) [Streptococcus suis strain LS9N]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYLYAYGEENSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRVSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=1145966 BUC38_RS00420 WP_044689742.1 78942..80123(+) (cinA) [Streptococcus suis strain LS9N]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACAGAAGATGACTTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGCTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGATCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAATTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATCTCTATGCCTACGGAGAGGAAAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGGTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8IGV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.183

100

0.962
  cinA Streptococcus pneumoniae Rx1

56.731

100

0.601
  cinA Streptococcus pneumoniae R6

56.731

100

0.601
  cinA Streptococcus mitis SK321

56.731

100

0.601
  cinA Streptococcus pneumoniae TIGR4

56.731

100

0.601
  cinA Streptococcus mitis NCTC 12261

56.49

100

0.598
  cinA Streptococcus pneumoniae D39

56.49

100

0.598
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Bacillus subtilis subsp. subtilis str. 168

40.921

99.491

0.407

Multiple sequence alignment