Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   LLA12_RS11740 Genome accession   NZ_LT599049
Coordinates   2382898..2383971 (-) Length   357 a.a.
NCBI ID   WP_080651957.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain A12     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2377898..2388971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLA12_RS11695 (LLA12_02480) - 2378036..2378845 (-) 810 WP_032946979.1 metal ABC transporter permease -
  LLA12_RS11700 (LLA12_02481) - 2378838..2379575 (-) 738 WP_021723055.1 metal ABC transporter ATP-binding protein -
  LLA12_RS11705 (LLA12_02482) - 2379753..2380595 (-) 843 WP_068872849.1 metal ABC transporter substrate-binding protein -
  LLA12_RS11710 (LLA12_02483) - 2380592..2381029 (-) 438 WP_021721874.1 zinc-dependent MarR family transcriptional regulator -
  LLA12_RS11715 (LLA12_02484) comGG 2381110..2381385 (-) 276 WP_021721873.1 hypothetical protein Machinery gene
  LLA12_RS11720 (LLA12_02485) comGF 2381433..2381879 (-) 447 WP_021721872.1 competence type IV pilus minor pilin ComGF Machinery gene
  LLA12_RS11725 (LLA12_02486) comGE 2381842..2382138 (-) 297 WP_021721871.1 competence type IV pilus minor pilin ComGE Machinery gene
  LLA12_RS11730 (LLA12_02487) comGD 2382110..2382541 (-) 432 WP_080651959.1 competence type IV pilus minor pilin ComGD Machinery gene
  LLA12_RS11735 (LLA12_02488) comGC 2382501..2382884 (-) 384 WP_080651958.1 competence type IV pilus major pilin ComGC Machinery gene
  LLA12_RS11740 (LLA12_02489) comGB 2382898..2383971 (-) 1074 WP_080651957.1 competence type IV pilus assembly protein ComGB Machinery gene
  LLA12_RS11745 (LLA12_02490) comGA 2383865..2384803 (-) 939 WP_032946550.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 40345.52 Da        Isoelectric Point: 10.3543

>NTDB_id=1144891 LLA12_RS11740 WP_080651957.1 2382898..2383971(-) (comGB) [Lactococcus lactis subsp. lactis strain A12]
MSLGHQKIGIKKLISYLQMDISHLLKPRGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQSLSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLIHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGQSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWKQFFTKID
RLMQLIQPLVFVFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=1144891 LLA12_RS11740 WP_080651957.1 2382898..2383971(-) (comGB) [Lactococcus lactis subsp. lactis strain A12]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACATCTACTGAAGCC
AAGAGGGAAAAAATTAAGACTGATTAAACAAGCTAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTGAAAATGAAAGAAGGTCTCGCT
TCTGGTCAATCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGAACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTATTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTGCCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGATTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTCGAA
TTACGTCAAATTATTAACTTAATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCAGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGAAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTGTTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCTATGTTACT
CCCCATCTATTCAAATATGGGTTCAGGAATATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(41-159)

Type II secretion system (T2SS), protein F (T2SSF)

(227-348)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

82.991

95.518

0.793
  comYB Streptococcus gordonii str. Challis substr. CH1

53.372

95.518

0.51
  comYB Streptococcus mutans UA159

53.079

95.518

0.507
  comYB Streptococcus mutans UA140

53.079

95.518

0.507
  comGB/cglB Streptococcus pneumoniae TIGR4

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae D39

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae R6

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae Rx1

51.045

93.838

0.479
  comGB/cglB Streptococcus mitis SK321

50.448

93.838

0.473
  comGB/cglB Streptococcus mitis NCTC 12261

50.149

93.838

0.471

Multiple sequence alignment