Detailed information NTG1144887

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: LLA12_RS11720
• Genome accession: NZ_LT599049
• Coordinates: 2381433..2381879 (-)
• Length: 148 a.a.
• NCBI ID: WP_021721872.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain A12
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2376433..2386879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLA12_RS11695 (LLA12_02480)	-	2378036..2378845 (-)	810	WP_032946979.1	metal ABC transporter permease	-
LLA12_RS11700 (LLA12_02481)	-	2378838..2379575 (-)	738	WP_021723055.1	metal ABC transporter ATP-binding protein	-
LLA12_RS11705 (LLA12_02482)	-	2379753..2380595 (-)	843	WP_068872849.1	metal ABC transporter substrate-binding protein	-
LLA12_RS11710 (LLA12_02483)	-	2380592..2381029 (-)	438	WP_021721874.1	zinc-dependent MarR family transcriptional regulator	-
LLA12_RS11715 (LLA12_02484)	comGG	2381110..2381385 (-)	276	WP_021721873.1	hypothetical protein	Machinery gene
LLA12_RS11720 (LLA12_02485)	comGF	2381433..2381879 (-)	447	WP_021721872.1	competence type IV pilus minor pilin ComGF	Machinery gene
LLA12_RS11725 (LLA12_02486)	comGE	2381842..2382138 (-)	297	WP_021721871.1	competence type IV pilus minor pilin ComGE	Machinery gene
LLA12_RS11730 (LLA12_02487)	comGD	2382110..2382541 (-)	432	WP_080651959.1	competence type IV pilus minor pilin ComGD	Machinery gene
LLA12_RS11735 (LLA12_02488)	comGC	2382501..2382884 (-)	384	WP_080651958.1	competence type IV pilus major pilin ComGC	Machinery gene
LLA12_RS11740 (LLA12_02489)	comGB	2382898..2383971 (-)	1074	WP_080651957.1	competence type IV pilus assembly protein ComGB	Machinery gene
LLA12_RS11745 (LLA12_02490)	comGA	2383865..2384803 (-)	939	WP_032946550.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 148 a.a.
• Molecular weight: 17156.02 Da
• Isoelectric Point: 9.0730

>NTDB_id=1144887 LLA12_RS11720 WP_021721872.1 2381433..2381879(-) (comGF) [Lactococcus lactis subsp. lactis strain A12]
MERKFCDLNLKVKAFTLLECLVALLAISGSVLVISGLTKMLKEQMAISQSDSIKDWQIFCQQMRFELSGTKLDKVEQNFL
YVTKDKKLRFGFMNDDFRKTDDKGQGYQPMLYDIKGAKIQATKNLITIRIDFNQGGERTFIYQFPEDK

Nucleotide

• Length: 447 bp

>NTDB_id=1144887 LLA12_RS11720 WP_021721872.1 2381433..2381879(-) (comGF) [Lactococcus lactis subsp. lactis strain A12]
ATGGAAAGGAAATTTTGCGACTTGAACCTCAAAGTTAAAGCATTTACCTTGTTGGAGTGTTTGGTGGCACTTCTTGCAAT
TTCTGGATCAGTCCTTGTCATCTCAGGTTTAACAAAGATGTTGAAAGAACAAATGGCGATTAGTCAAAGTGATAGCATAA
AAGATTGGCAAATTTTCTGTCAGCAAATGCGTTTTGAACTCTCAGGAACAAAATTAGATAAGGTAGAACAGAATTTTCTA
TATGTAACTAAAGATAAAAAACTAAGGTTTGGTTTTATGAATGATGATTTCCGGAAGACTGATGACAAAGGTCAGGGTTA
TCAGCCAATGCTTTATGATATAAAAGGGGCTAAGATTCAAGCTACTAAAAATCTAATAACCATAAGAATTGATTTTAATC
AAGGAGGTGAAAGAACATTTATCTATCAATTTCCAGAAGACAAATAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (48-137)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Lactococcus lactis subsp. cremoris KW2	78.014	95.27	0.743
comYF	Streptococcus mutans UA140	48.227	95.27	0.459
comYF	Streptococcus mutans UA159	47.518	95.27	0.453
comGF/cglF	Streptococcus mitis SK321	42.143	94.595	0.399
comGF/cglF	Streptococcus pneumoniae Rx1	40.714	94.595	0.385
comGF/cglF	Streptococcus pneumoniae D39	40.714	94.595	0.385
comGF/cglF	Streptococcus pneumoniae R6	40.714	94.595	0.385
comGF/cglF	Streptococcus pneumoniae TIGR4	40.714	94.595	0.385
comGF/cglF	Streptococcus mitis NCTC 12261	40.714	94.595	0.385