Detailed information NTG1143678

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: BJR96_RS01155
• Genome accession: NZ_LT545678
• Coordinates: 201178..201507 (+)
• Length: 109 a.a.
• NCBI ID: WP_000793380.1
• Uniprot ID: A0A0E1EKJ1
• Organism: Streptococcus agalactiae isolate SA111
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 196178..206507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJR96_RS01135 (SA111_00213)	-	197172..197537 (+)	366	WP_000285374.1	DUF1033 family protein	-
BJR96_RS01140 (SA111_00214)	-	197767..199227 (+)	1461	WP_000468685.1	IS1182-like element IS1563 family transposase	-
BJR96_RS01145 (SA111_00215)	comYA	199273..200244 (+)	972	WP_000250798.1	competence type IV pilus ATPase ComGA	Machinery gene
BJR96_RS01150 (SA111_00216)	comYB	200138..201181 (+)	1044	WP_261368811.1	competence type IV pilus assembly protein ComGB	Machinery gene
BJR96_RS01155 (SA111_00217)	comGC/cglC	201178..201507 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
BJR96_RS01160 (SA111_00218)	comYD	201482..201895 (+)	414	WP_000244259.1	competence type IV pilus minor pilin ComGD	Machinery gene
BJR96_RS01165 (SA111_00219)	comGE	201867..202166 (+)	300	WP_001872488.1	competence type IV pilus minor pilin ComGE	-
BJR96_RS01170 (SA111_00220)	comGF	202120..202581 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	-
BJR96_RS01175 (SA111_00221)	comGG	202559..202930 (+)	372	WP_000601101.1	competence type IV pilus minor pilin ComGG	-
BJR96_RS01180 (SA111_00222)	comYH	203045..204019 (+)	975	WP_001008569.1	class I SAM-dependent methyltransferase	Machinery gene
BJR96_RS01185 (SA111_00223)	-	204051..205244 (+)	1194	WP_000047534.1	acetate kinase	-
BJR96_RS01190	-	205372..205564 (+)	193	Protein_180	helix-turn-helix transcriptional regulator	-
BJR96_RS01195	-	205543..205830 (+)	288	Protein_181	hypothetical protein	-

Sequence

Protein

• Length: 109 a.a.
• Molecular weight: 12129.27 Da
• Isoelectric Point: 10.0311

>NTDB_id=1143678 BJR96_RS01155 WP_000793380.1 201178..201507(+) (comGC/cglC) [Streptococcus agalactiae isolate SA111]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide

• Length: 330 bp

>NTDB_id=1143678 BJR96_RS01155 WP_000793380.1 201178..201507(+) (comGC/cglC) [Streptococcus agalactiae isolate SA111]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• AlphaFold DB: A0A0E1EKJ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	60.55	100	0.606
comGC/cglC	Streptococcus mitis SK321	59.633	100	0.596
comYC	Streptococcus gordonii str. Challis substr. CH1	61.165	94.495	0.578
comGC/cglC	Streptococcus pneumoniae TIGR4	57.798	100	0.578
comGC/cglC	Streptococcus pneumoniae R6	57.798	100	0.578
comGC/cglC	Streptococcus pneumoniae Rx1	57.798	100	0.578
comGC/cglC	Streptococcus pneumoniae D39	57.798	100	0.578
comYC	Streptococcus mutans UA159	55.238	96.33	0.532
comYC	Streptococcus mutans UA140	55.238	96.33	0.532
comGC	Lactococcus lactis subsp. cremoris KW2	63.043	84.404	0.532
comYC	Streptococcus suis isolate S10	65.854	75.229	0.495