Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL12_RS09995 Genome accession   NZ_LS483450
Coordinates   1842523..1843779 (-) Length   418 a.a.
NCBI ID   WP_000642707.1    Uniprot ID   A0A0B7L5W3
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1837523..1848779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS09965 - 1837563..1837769 (-) 207 WP_050247812.1 hypothetical protein -
  DQL12_RS09970 - 1837756..1837929 (-) 174 WP_001056002.1 helix-turn-helix domain-containing protein -
  DQL12_RS09975 lytA 1838294..1839250 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  DQL12_RS09980 - 1839626..1840996 (-) 1371 WP_001036243.1 MATE family efflux transporter -
  DQL12_RS09990 recA 1841302..1842468 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  DQL12_RS09995 cinA 1842523..1843779 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  DQL12_RS10000 brpA 1843863..1844879 (-) 1017 WP_050202865.1 biofilm formation/cell division transcriptional regulator BrpA -
  DQL12_RS10005 - 1844887..1845405 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  DQL12_RS10010 tsaE 1845395..1845838 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  DQL12_RS10015 comM 1845924..1846544 (-) 621 WP_000839910.1 hypothetical protein Regulator
  DQL12_RS10025 - 1846927..1847790 (-) 864 WP_050255560.1 helix-turn-helix domain-containing protein -
  DQL12_RS12505 - 1847978..1848147 (+) 170 Protein_1865 PhrA family quorum-sensing system peptide -
  DQL12_RS10035 - 1848462..1848758 (+) 297 WP_000911560.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45061.46 Da        Isoelectric Point: 4.6027

>NTDB_id=1142001 DQL12_RS09995 WP_000642707.1 1842523..1843779(-) (cinA) [Streptococcus pneumoniae strain 4041STDY6583227]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1142001 DQL12_RS09995 WP_000642707.1 1842523..1843779(-) (cinA) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCTTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7L5W3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.761

100

0.998
  cinA Streptococcus pneumoniae Rx1

99.522

100

0.995
  cinA Streptococcus pneumoniae R6

99.522

100

0.995
  cinA Streptococcus pneumoniae D39

99.282

100

0.993
  cinA Streptococcus mitis SK321

93.78

100

0.938
  cinA Streptococcus mitis NCTC 12261

93.541

100

0.935
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment