Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQN91_RS02310 Genome accession   NZ_LS483441
Coordinates   485543..486784 (-) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain NCTC12244     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 480543..491784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN91_RS02280 (NCTC12244_00458) - 481337..482521 (+) 1185 WP_042015096.1 tetratricopeptide repeat protein -
  DQN91_RS02285 (NCTC12244_00459) mutT 482530..482934 (+) 405 WP_171864957.1 8-oxo-dGTP diphosphatase MutT -
  DQN91_RS02290 (NCTC12244_00460) yacG 482992..483186 (-) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  DQN91_RS02295 (NCTC12244_00461) zapD 483197..483919 (-) 723 WP_010675825.1 cell division protein ZapD -
  DQN91_RS02300 (NCTC12244_00462) coaE 483957..484571 (-) 615 WP_042015097.1 dephospho-CoA kinase -
  DQN91_RS02305 (NCTC12244_00463) pilD 484590..485465 (-) 876 WP_042015098.1 A24 family peptidase Machinery gene
  DQN91_RS02310 (NCTC12244_00464) pilC 485543..486784 (-) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  DQN91_RS02315 (NCTC12244_00465) pilB 486912..488618 (-) 1707 WP_041213997.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  DQN91_RS02320 - 488622..489056 (-) 435 WP_042015100.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  DQN91_RS02325 (NCTC12244_00466) nadC 489367..490230 (-) 864 WP_041213995.1 carboxylating nicotinate-nucleotide diphosphorylase -
  DQN91_RS02330 (NCTC12244_00467) - 490234..490704 (-) 471 WP_042015101.1 TIGR02281 family clan AA aspartic protease -
  DQN91_RS02335 (NCTC12244_00468) ampD 490833..491405 (+) 573 WP_042015103.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=1141600 DQN91_RS02310 WP_010675822.1 485543..486784(-) (pilC) [Aeromonas caviae strain NCTC12244]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=1141600 DQN91_RS02310 WP_010675822.1 485543..486784(-) (pilC) [Aeromonas caviae strain NCTC12244]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTTATCTCCCGC
CAGATCACCACTATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCCCGCGGCCACGAGAAAGCGGC
GGTGCGCGAGCTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGATCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCTGCCTTCACCCGGTTCGTCATCGCCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCTGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTCTCTACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCCCTGGTCTCGGCGGCCGGAGCATCCGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375

Multiple sequence alignment