Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQN42_RS08380 Genome accession   NZ_LS483436
Coordinates   1700806..1701828 (-) Length   340 a.a.
NCBI ID   WP_172634362.1    Uniprot ID   -
Organism   Streptococcus intermedius strain NCTC11324     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1695806..1706828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN42_RS08345 (NCTC11324_01680) - 1696821..1698020 (-) 1200 WP_003076127.1 acetate kinase -
  DQN42_RS08350 (NCTC11324_01681) comYH 1698067..1699020 (-) 954 WP_003075742.1 class I SAM-dependent methyltransferase Machinery gene
  DQN42_RS08355 (NCTC11324_01682) comGG 1699111..1699437 (-) 327 WP_014829817.1 competence type IV pilus minor pilin ComGG -
  DQN42_RS08360 (NCTC11324_01683) comGF/cglF 1699418..1699855 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN42_RS08365 (NCTC11324_01684) comGE/cglE 1699839..1700132 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN42_RS08370 (NCTC11324_01685) comYD 1700104..1700532 (-) 429 WP_014829819.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN42_RS08375 (NCTC11324_01686) comYC 1700492..1700809 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN42_RS08380 (NCTC11324_01687) comYB 1700806..1701828 (-) 1023 WP_172634362.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN42_RS08385 (NCTC11324_01688) comYA 1701770..1702711 (-) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN42_RS08390 (NCTC11324_01689) - 1702780..1703145 (-) 366 WP_003075933.1 DUF1033 family protein -
  DQN42_RS08395 (NCTC11324_01690) glnA 1703367..1704713 (-) 1347 WP_003076201.1 type I glutamate--ammonia ligase -
  DQN42_RS08400 (NCTC11324_01691) - 1704752..1705111 (-) 360 WP_003073972.1 MerR family transcriptional regulator -
  DQN42_RS08405 (NCTC11324_01692) - 1705188..1705718 (-) 531 WP_003073971.1 aromatic acid exporter family protein -
  DQN42_RS08410 (NCTC11324_01693) - 1705893..1706573 (-) 681 WP_003075761.1 CHAP domain-containing protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39213.42 Da        Isoelectric Point: 9.8352

>NTDB_id=1141471 DQN42_RS08380 WP_172634362.1 1700806..1701828(-) (comYB) [Streptococcus intermedius strain NCTC11324]
MQQDISILNRQKRKKLSTVKQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEKAYVEKMKEGLATGKPFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENISKVKKKLIEVATYPFILFIFLVFIMLGLRNYLLPQLESQNIATQLISRLPQ
IFLGSVGVVFVLFAIGFYWFRKSSQIRVFSLLSRLPFWGTFVQTYLTAYYAREWGNMIGQGLELSQIFRMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLMIEYGEVKSKLGCELEVYAQKTWEVFFKRVHQAMNIIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=1141471 DQN42_RS08380 WP_172634362.1 1700806..1701828(-) (comYB) [Streptococcus intermedius strain NCTC11324]
ATGCAGCAGGACATATCAATCTTGAACAGGCAAAAGCGGAAAAAATTATCCACAGTTAAGCAGAAAAAAGTCGTAGAGTT
ACTAAATAATCTTTTTTCTAGTGGTTTTCACTTGGCAGAAATTATTGATTTTTTGAAACGGAGTGCTTTGTTAGAAAAAG
CCTATGTGGAAAAGATGAAAGAGGGGTTGGCAACCGGAAAGCCTTTTTCAGACATCATGGCAAGTTTAGGTTTTTCGGAT
AATGTAGTAACACAGCTTTCATTGGCAGAATTGCATGGAAATTTATCGCTCAGTTTGAGTAAAATTGAAGAGTATTTGGA
AAATATCTCAAAAGTCAAGAAAAAGTTAATTGAAGTGGCGACTTATCCATTTATTTTATTCATTTTTCTAGTGTTTATTA
TGTTAGGGCTGCGCAATTATTTGTTACCGCAGTTGGAGAGTCAGAATATTGCAACACAACTGATTAGTCGTTTACCACAA
ATTTTTCTGGGTTCAGTAGGAGTTGTTTTTGTTTTGTTTGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCACAAATAAG
AGTATTTAGTTTGTTGTCTCGACTTCCTTTTTGGGGCACTTTTGTTCAAACCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGGAATATGATTGGTCAAGGCTTAGAACTCAGTCAGATTTTCCGGATGATGCAAGGACAGCGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAGTAGCACTGCAAAATGGTCAGGAATTTTCACAAGTAGTTAAACATTATCCATTTTTTAA
AAAAGAATTGGGCTTGATGATCGAATATGGGGAAGTGAAATCCAAATTGGGGTGCGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGGTGTTTTTTAAACGTGTTCATCAAGCGATGAATATCATTCAGCCATTAGTATTTGTCTTTGTGGCGTTGATG
ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.235

100

0.732
  comGB/cglB Streptococcus mitis NCTC 12261

69.254

98.529

0.682
  comGB/cglB Streptococcus mitis SK321

68.955

98.529

0.679
  comGB/cglB Streptococcus pneumoniae TIGR4

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae R6

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae Rx1

68.358

98.529

0.674
  comGB/cglB Streptococcus pneumoniae D39

68.358

98.529

0.674
  comYB Streptococcus mutans UA140

61.111

100

0.615
  comYB Streptococcus mutans UA159

61.111

100

0.615
  comGB Lactococcus lactis subsp. cremoris KW2

51.929

99.118

0.515

Multiple sequence alignment