Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQN42_RS08365 Genome accession   NZ_LS483436
Coordinates   1699839..1700132 (-) Length   97 a.a.
NCBI ID   WP_003073987.1    Uniprot ID   -
Organism   Streptococcus intermedius strain NCTC11324     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1694839..1705132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN42_RS08345 (NCTC11324_01680) - 1696821..1698020 (-) 1200 WP_003076127.1 acetate kinase -
  DQN42_RS08350 (NCTC11324_01681) comYH 1698067..1699020 (-) 954 WP_003075742.1 class I SAM-dependent methyltransferase Machinery gene
  DQN42_RS08355 (NCTC11324_01682) comGG 1699111..1699437 (-) 327 WP_014829817.1 competence type IV pilus minor pilin ComGG -
  DQN42_RS08360 (NCTC11324_01683) comGF/cglF 1699418..1699855 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN42_RS08365 (NCTC11324_01684) comGE/cglE 1699839..1700132 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN42_RS08370 (NCTC11324_01685) comYD 1700104..1700532 (-) 429 WP_014829819.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN42_RS08375 (NCTC11324_01686) comYC 1700492..1700809 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN42_RS08380 (NCTC11324_01687) comYB 1700806..1701828 (-) 1023 WP_172634362.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN42_RS08385 (NCTC11324_01688) comYA 1701770..1702711 (-) 942 WP_003073980.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN42_RS08390 (NCTC11324_01689) - 1702780..1703145 (-) 366 WP_003075933.1 DUF1033 family protein -
  DQN42_RS08395 (NCTC11324_01690) glnA 1703367..1704713 (-) 1347 WP_003076201.1 type I glutamate--ammonia ligase -
  DQN42_RS08400 (NCTC11324_01691) - 1704752..1705111 (-) 360 WP_003073972.1 MerR family transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11195.24 Da        Isoelectric Point: 10.4670

>NTDB_id=1141468 DQN42_RS08365 WP_003073987.1 1699839..1700132(-) (comGE/cglE) [Streptococcus intermedius strain NCTC11324]
MENLRKQYVRGTILLEALLALAIFATIVTLLLGQIHQSRKLENELLKKEEVLRVAKMALQTNQRHLTMNGIEVRVEKSQQ
DIRVYHGKELIFGVQSK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1141468 DQN42_RS08365 WP_003073987.1 1699839..1700132(-) (comGE/cglE) [Streptococcus intermedius strain NCTC11324]
ATGGAAAATTTAAGAAAACAATATGTTAGAGGGACAATTTTATTAGAAGCACTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTAACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAACTAGAAAATGAGTTATTGAAAAAAGAAGAAGTCTTAAGGG
TAGCGAAGATGGCCTTGCAAACAAATCAAAGGCATTTAACAATGAACGGTATTGAAGTACGTGTCGAAAAAAGCCAACAA
GATATTCGGGTTTATCATGGGAAGGAGCTGATTTTTGGTGTTCAAAGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-91)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comYE Streptococcus mutans UA140

48.352

93.814

0.454
  comYE Streptococcus mutans UA159

48.352

93.814

0.454

Multiple sequence alignment