Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQN21_RS12110 Genome accession   NZ_LS483409
Coordinates   2417982..2419241 (-) Length   419 a.a.
NCBI ID   WP_077497920.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2412982..2424241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS12900 - 2414533..2414661 (-) 129 WP_099046295.1 hypothetical protein -
  DQN21_RS12085 (NCTC13773_02453) - 2414753..2415070 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  DQN21_RS12090 (NCTC13773_02454) ruvX 2415103..2415522 (-) 420 WP_009855163.1 Holliday junction resolvase RuvX -
  DQN21_RS12095 (NCTC13773_02455) - 2415519..2415788 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  DQN21_RS12100 (NCTC13773_02456) spx 2416110..2416508 (-) 399 WP_009855164.1 transcriptional regulator Spx -
  DQN21_RS12105 (NCTC13773_02457) recA 2416778..2417932 (-) 1155 WP_009855165.1 recombinase RecA Machinery gene
  DQN21_RS12110 (NCTC13773_02458) cinA 2417982..2419241 (-) 1260 WP_077497920.1 competence/damage-inducible protein A Machinery gene
  DQN21_RS12115 (NCTC13773_02459) - 2419373..2420563 (-) 1191 WP_077497922.1 MFS transporter -
  DQN21_RS12655 - 2420723..2420896 (-) 174 WP_167367618.1 hypothetical protein -
  DQN21_RS12120 (NCTC13773_02460) - 2420946..2421410 (-) 465 WP_077497924.1 hypothetical protein -
  DQN21_RS12125 (NCTC13773_02461) - 2421480..2421887 (-) 408 WP_077497926.1 hypothetical protein -
  DQN21_RS12130 (NCTC13773_02462) - 2422050..2422891 (+) 842 Protein_2333 helix-turn-helix domain-containing protein -
  DQN21_RS12135 (NCTC13773_02464) ruvA 2422965..2423558 (-) 594 WP_009855172.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45453.81 Da        Isoelectric Point: 5.0671

>NTDB_id=1140595 DQN21_RS12110 WP_077497920.1 2417982..2419241(-) (cinA) [Streptococcus gallolyticus strain NCTC13773]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNDVTYVVLPGPPSELKPM
VLDSLVPLLSGNHKQLYSRVLRFFGIGESQLVTVLTDLIDNQTDPTIAPYAKTGEVTLRLSTKADDVASAKAKLDALEHK
ILAKKTLNSIPLEQLLYGYGDDNSMARVVFDLLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTNADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1140595 DQN21_RS12110 WP_077497920.1 2417982..2419241(-) (cinA) [Streptococcus gallolyticus strain NCTC13773]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGATGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGACGTGACCTACGTTGTTCTCCCTGGACCGCCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTACCTTTATTGTCTGGAAACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTTTTGACAGATTTGATTGATAATCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGGCGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTACTTTATGGCTATGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACTATTACAGCGGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTGAAGATTTGCAAGAACATGGTGTGGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAAATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACACCCAGCAGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.422

99.523

0.721
  cinA Streptococcus mitis SK321

71.053

99.761

0.709
  cinA Streptococcus mitis NCTC 12261

70.813

99.761

0.706
  cinA Streptococcus pneumoniae Rx1

69.856

99.761

0.697
  cinA Streptococcus pneumoniae TIGR4

69.856

99.761

0.697
  cinA Streptococcus pneumoniae R6

69.856

99.761

0.697
  cinA Streptococcus pneumoniae D39

69.617

99.761

0.695
  cinA Streptococcus suis isolate S10

53.606

99.284

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

45.972

100

0.463

Multiple sequence alignment