Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   DQM80_RS00600 Genome accession   NZ_LS483399
Coordinates   97731..98057 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8227     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92731..103057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM80_RS00585 (NCTC8227_00119) - 95361..95726 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQM80_RS00590 (NCTC8227_00120) comGA 95819..96758 (+) 940 Protein_79 competence type IV pilus ATPase ComGA -
  DQM80_RS00595 (NCTC8227_00121) comGB 96694..97729 (+) 1036 Protein_80 competence type IV pilus assembly protein ComGB -
  DQM80_RS00600 (NCTC8227_00122) comYC 97731..98057 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM80_RS00605 (NCTC8227_00123) comGD 98032..98460 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  DQM80_RS00610 (NCTC8227_00124) comGE 98417..98701 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQM80_RS00615 (NCTC8227_00125) comYF 98694..99128 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM80_RS00620 (NCTC8227_00126) comGG 99112..99438 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  DQM80_RS00625 (NCTC8227_00127) comYH 99536..100489 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  DQM80_RS00630 (NCTC8227_00128) - 100548..101744 (+) 1197 WP_020904834.1 acetate kinase -
  DQM80_RS00635 - 101931..102239 (+) 309 WP_011017251.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=1140207 DQM80_RS00600 WP_002986552.1 97731..98057(+) (comYC) [Streptococcus pyogenes strain NCTC8227]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1140207 DQM80_RS00600 WP_002986552.1 97731..98057(+) (comYC) [Streptococcus pyogenes strain NCTC8227]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment