Detailed information NTG1140144

Bioinformatically predicted

Overview

• Name: comGA/cglA
• Type: Machinery gene
• Locus tag: DQM95_RS00765
• Genome accession: NZ_LS483397
• Coordinates: 123774..124715 (+)
• Length: 313 a.a.
• NCBI ID: WP_037592994.1
• Uniprot ID: -
• Organism: Streptococcus uberis strain NCTC3858
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118774..129715

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM95_RS00755 (NCTC3858_00154)	rpoC	119577..123215 (+)	3639	WP_111685884.1	DNA-directed RNA polymerase subunit beta'	-
DQM95_RS00760 (NCTC3858_00155)	-	123336..123701 (+)	366	WP_041817508.1	DUF1033 family protein	-
DQM95_RS00765 (NCTC3858_00156)	comGA/cglA	123774..124715 (+)	942	WP_037592994.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM95_RS00770 (NCTC3858_00157)	comYB	124648..125682 (+)	1035	WP_408646205.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM95_RS00780 (NCTC3858_00159)	-	125763..127208 (-)	1446	WP_037592992.1	recombinase family protein	-
DQM95_RS00785 (NCTC3858_00160)	-	127358..127807 (-)	450	WP_037592991.1	Ltp family lipoprotein	-
DQM95_RS00790 (NCTC3858_00161)	-	127860..128237 (-)	378	WP_037593023.1	ImmA/IrrE family metallo-endopeptidase	-
DQM95_RS00795 (NCTC3858_00162)	-	128221..128583 (-)	363	WP_037592990.1	helix-turn-helix domain-containing protein	-
DQM95_RS00800 (NCTC3858_00163)	-	128774..128974 (+)	201	WP_037592989.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35707.07 Da
• Isoelectric Point: 6.7690

>NTDB_id=1140144 DQM95_RS00765 WP_037592994.1 123774..124715(+) (comGA/cglA) [Streptococcus uberis strain NCTC3858]
MIQSLGMQLIQEASLKQAQDIYLIPQKDSYQVFMRVGDSRQKIGDYEWKDAINLISHFKFVAGMNVGEKRRTQLGSCDYH
IDQQCLVSLRLSTVGDYRGHESLVIRLLATQESQLHYWFDSFERIEKAIHGRGLYLFAGPVGSGKTRLMYALMEKYMQDS
QIITIEDPVEIKQDAILQLQVNNSIGMTYDNLIKLSLRHRPDLVIIGEIRDTETAQAVIRASLTGAMVFSTIHAKSIPGV
FSRLIELGVKRDELLNCLNLIAYQRLIAGGGLIDFATEKFEEHTHNQWNQEVEQLLKQGYIDNEKAKLEKIKG

Nucleotide

• Length: 942 bp

>NTDB_id=1140144 DQM95_RS00765 WP_037592994.1 123774..124715(+) (comGA/cglA) [Streptococcus uberis strain NCTC3858]
ATGATACAAAGCTTAGGCATGCAATTGATTCAAGAAGCCAGTCTCAAACAAGCACAAGATATTTATCTCATACCTCAAAA
AGACTCTTATCAAGTTTTTATGAGAGTTGGAGATAGTCGGCAAAAAATAGGAGATTATGAGTGGAAGGATGCGATAAATC
TCATTAGTCATTTTAAATTTGTCGCAGGTATGAATGTTGGCGAGAAAAGAAGAACACAACTAGGGTCCTGTGATTATCAC
ATAGATCAGCAATGCCTTGTCTCCTTGAGACTGTCAACAGTGGGTGACTATCGCGGGCATGAAAGTTTGGTTATCCGCCT
TTTAGCCACACAAGAGTCACAATTACATTATTGGTTTGACAGTTTTGAAAGGATTGAAAAAGCCATTCATGGTCGAGGTC
TTTATTTATTTGCTGGTCCAGTAGGTTCAGGTAAAACACGGTTGATGTACGCGTTAATGGAAAAATATATGCAGGACAGC
CAAATTATTACGATTGAAGATCCTGTTGAGATTAAGCAAGATGCTATTTTACAACTCCAAGTCAATAATAGTATTGGAAT
GACTTATGATAACCTGATTAAATTGTCTTTGAGGCATCGGCCTGATTTAGTGATTATAGGTGAAATACGTGATACAGAAA
CAGCACAGGCTGTTATTAGAGCAAGTTTGACGGGGGCCATGGTTTTCTCGACCATTCATGCTAAGAGCATTCCAGGAGTT
TTCTCTCGACTGATTGAACTCGGTGTAAAACGAGATGAATTGTTAAACTGTCTCAATTTGATAGCTTATCAACGGTTAAT
TGCAGGAGGAGGGCTAATTGATTTTGCCACAGAAAAATTCGAAGAGCATACCCATAATCAATGGAATCAAGAGGTTGAGC
AACTTCTTAAACAAGGATATATCGATAACGAAAAAGCCAAGTTGGAAAAAATTAAAGGCTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	63.023	99.361	0.626
comYA	Streptococcus mutans UA140	62.5	99.681	0.623
comYA	Streptococcus mutans UA159	62.5	99.681	0.623
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	62.058	99.361	0.617
comGA/cglA/cilD	Streptococcus pneumoniae D39	61.415	99.361	0.61
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	61.415	99.361	0.61
comGA/cglA/cilD	Streptococcus pneumoniae R6	61.415	99.361	0.61
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	61.415	99.361	0.61
comYA	Streptococcus gordonii str. Challis substr. CH1	58.654	99.681	0.585
comGA	Lactococcus lactis subsp. cremoris KW2	51.125	99.361	0.508