Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   DQM63_RS03505 Genome accession   NZ_LS483385
Coordinates   675138..675818 (+) Length   226 a.a.
NCBI ID   WP_032911181.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 670138..680818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS03485 (NCTC7863_00679) - 670258..671004 (-) 747 WP_002897979.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQM63_RS03490 (NCTC7863_00680) - 671132..673471 (-) 2340 WP_002902647.1 cation-translocating P-type ATPase -
  DQM63_RS03495 (NCTC7863_00681) - 673629..674369 (+) 741 WP_002900842.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DQM63_RS03500 (NCTC7863_00682) - 674442..674990 (+) 549 WP_169449407.1 HXXEE domain-containing protein -
  DQM63_RS03505 (NCTC7863_00683) comEA 675138..675818 (+) 681 WP_032911181.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQM63_RS03510 (NCTC7863_00684) comEC/celB 675802..678042 (+) 2241 WP_002913774.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQM63_RS03515 (NCTC7863_00685) - 678171..679298 (+) 1128 WP_004191883.1 DUF805 domain-containing protein -
  DQM63_RS03520 (NCTC7863_00686) holA 679550..680596 (+) 1047 WP_002900833.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 23873.63 Da        Isoelectric Point: 4.7313

>NTDB_id=1139624 DQM63_RS03505 WP_032911181.1 675138..675818(+) (comEA) [Streptococcus sanguinis strain NCTC7863]
MLEEIIEKLKEYKLFVGLAVVGAVLGAFFLIKGNHQPQNQVAALSQDVTSSSSSADEESEKIVSKGKADEEESEQVTVDI
KGAVKNPGVYELRAGARVHEAIQKAGGLTADAEAKSINQAQKLTDEAVIYVAKIGEEGADVTQTGQRQAGASDSAGASGG
KSDKVNLNTATEAELQTISGIGQKRASDIIAYRESSGRFKSVDDLKKVSGIGDKTLEKLKEYVTVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=1139624 DQM63_RS03505 WP_032911181.1 675138..675818(+) (comEA) [Streptococcus sanguinis strain NCTC7863]
ATGCTTGAAGAAATCATTGAAAAGCTGAAAGAATACAAGCTCTTTGTTGGTCTAGCAGTAGTTGGCGCTGTGCTAGGTGC
TTTTTTCCTCATCAAGGGAAATCACCAGCCGCAAAATCAGGTAGCCGCCTTGAGCCAAGATGTAACTTCCTCATCCAGCT
CAGCTGATGAAGAAAGCGAAAAGATTGTCTCTAAGGGCAAGGCGGACGAAGAGGAGAGTGAGCAGGTCACTGTGGATATT
AAAGGCGCAGTTAAGAATCCTGGTGTCTATGAGCTGAGAGCAGGAGCGAGAGTCCATGAAGCCATCCAAAAAGCTGGCGG
ATTGACAGCAGACGCCGAGGCTAAGTCCATTAATCAGGCACAAAAATTAACGGATGAAGCAGTAATCTATGTGGCAAAGA
TTGGTGAAGAAGGAGCTGATGTCACCCAGACTGGCCAGCGTCAAGCAGGAGCTTCTGATTCTGCTGGTGCCAGTGGTGGA
AAGTCGGACAAGGTCAATCTAAATACGGCGACAGAGGCTGAACTGCAGACTATTTCAGGCATCGGACAGAAGCGGGCTTC
TGACATTATCGCCTACCGCGAAAGCAGTGGCCGTTTCAAGTCAGTAGATGATCTGAAAAAGGTGTCAGGTATTGGAGATA
AGACCTTAGAAAAGCTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(162-224)

SLBB domain (SLBB)

(78-131)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

50.431

100

0.518
  comEA/celA/cilE Streptococcus pneumoniae D39

50

100

0.513
  comEA/celA/cilE Streptococcus pneumoniae R6

50

100

0.513
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50

100

0.513
  comEA/celA/cilE Streptococcus mitis NCTC 12261

49.569

100

0.509
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.138

100

0.504
  comEA/celA/cilE Streptococcus mitis SK321

48.707

100

0.5
  comEA Bacillus subtilis subsp. subtilis str. 168

43.439

97.788

0.425
  comEA Lactococcus lactis subsp. cremoris KW2

39.823

100

0.398
  comEA Latilactobacillus sakei subsp. sakei 23K

34.025

100

0.363

Multiple sequence alignment