Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DQM63_RS03510 Genome accession   NZ_LS483385
Coordinates   675802..678042 (+) Length   746 a.a.
NCBI ID   WP_002913774.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 670802..683042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS03490 (NCTC7863_00680) - 671132..673471 (-) 2340 WP_002902647.1 cation-translocating P-type ATPase -
  DQM63_RS03495 (NCTC7863_00681) - 673629..674369 (+) 741 WP_002900842.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DQM63_RS03500 (NCTC7863_00682) - 674442..674990 (+) 549 WP_169449407.1 HXXEE domain-containing protein -
  DQM63_RS03505 (NCTC7863_00683) comEA 675138..675818 (+) 681 WP_032911181.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQM63_RS03510 (NCTC7863_00684) comEC/celB 675802..678042 (+) 2241 WP_002913774.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQM63_RS03515 (NCTC7863_00685) - 678171..679298 (+) 1128 WP_004191883.1 DUF805 domain-containing protein -
  DQM63_RS03520 (NCTC7863_00686) holA 679550..680596 (+) 1047 WP_002900833.1 DNA polymerase III subunit delta -
  DQM63_RS03525 (NCTC7863_00687) sodA 680659..681264 (+) 606 WP_002900832.1 superoxide dismutase SodA -
  DQM63_RS03530 (NCTC7863_00688) - 681400..682479 (+) 1080 WP_282184977.1 serine hydrolase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84854.82 Da        Isoelectric Point: 7.5832

>NTDB_id=1139625 DQM63_RS03510 WP_002913774.1 675802..678042(+) (comEC/celB) [Streptococcus sanguinis strain NCTC7863]
MSQWIKKLPLAPIYLAFILVWAYFAVYSGSSLAYFGLGVLLLRLFFSYPLKKSLAALAFLSLFVLFFLLCREIAEQAFRQ
EPPSASSVQVLPDTIKVNGDSLSFRGRANDQLYQVFYKIKSASEKEAFQQLTDLVVLDIEAEFEQAQQQRNFSGFDYQAY
LKSQGIYRALKINKIQSLRPISSLNPLDWLSVWRRKALVYIRNNFPSPMSHYMTGLLFGDLDTEFAEMSDLYSSLGIIHL
FALSGMQVGFFLDGFRRILLRLGMKRETVNALQLPFSFIYAGLTGFSVSVVRSLVQKLLAQQGLTRLDNFALTLTVLFII
MPNFLLTAGGVLSCAYAFLISMMDFEKLPPIRKLLAESLTISLGILPILIYYFSEFQPWSVILTFLFSLLFDLLMLPGLT
LIFILSPLLKITQVNFFFELLEDVIRWVADFAPRPLIFGKPNLWLLATLLLVLALIYDFRRKKSWLLSFSLLTLLLFFLT
KHPLQNEITVVDIGQGDSIFLRDWQGRTILIDVGGRVEIGKKEAWQERQTSSNAEKTLIPYLKSRGVGSLDVLVLTHTDT
DHMGDMLEVAQHFSIKEIYVSKGSLTQPDFVQKLEQIESSVHVVEVGDEIPVFDSALQVLYPSGTGDGGNDDSIVLYGEF
FQTKFLFTGDLERQGETELLQRFPQLKADVLKAGHHGSKGSSSPEFLEQIQPKLALISAGQNNRYRHPHQETLQRFEKFN
TAIYRTDQQGAIRLIGWNSWRIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=1139625 DQM63_RS03510 WP_002913774.1 675802..678042(+) (comEC/celB) [Streptococcus sanguinis strain NCTC7863]
ATGTCACAGTGGATTAAAAAGTTACCCCTCGCCCCTATCTATCTGGCTTTCATACTTGTATGGGCCTATTTTGCAGTCTA
TTCTGGCAGTTCCTTGGCTTATTTTGGGCTAGGTGTCCTTCTACTTCGTCTCTTTTTCAGTTATCCTCTCAAAAAGAGTC
TAGCTGCCTTGGCATTCCTGTCCCTTTTTGTCCTCTTTTTCTTGCTTTGTCGGGAAATAGCAGAGCAGGCCTTTAGGCAG
GAACCTCCTTCAGCTAGCTCGGTTCAGGTCTTGCCAGATACGATCAAAGTCAATGGAGATTCCCTATCCTTTCGAGGGCG
AGCAAACGATCAGCTTTATCAGGTCTTCTACAAGATCAAATCAGCCAGTGAAAAGGAAGCTTTTCAGCAATTGACAGATT
TGGTCGTCCTTGATATTGAAGCAGAGTTTGAACAGGCCCAGCAGCAACGAAATTTTTCGGGCTTTGACTATCAGGCTTAT
TTAAAGAGTCAGGGGATTTACCGTGCCTTAAAAATCAATAAGATTCAGTCACTAAGACCAATTTCCAGCCTTAATCCACT
CGATTGGCTATCTGTCTGGCGCAGAAAAGCGCTGGTCTATATTCGAAATAATTTTCCTAGTCCAATGAGTCATTATATGA
CTGGACTCCTGTTTGGTGACTTGGATACGGAGTTTGCGGAAATGAGTGACCTATATTCTAGCTTGGGTATCATCCATTTG
TTTGCCTTGTCTGGTATGCAGGTCGGTTTCTTTTTGGATGGTTTTCGCAGAATTCTTCTACGTTTGGGGATGAAGAGGGA
GACAGTAAATGCCTTGCAGCTGCCTTTTTCATTTATCTATGCTGGACTGACAGGCTTTTCTGTTTCTGTCGTTAGAAGCT
TAGTTCAGAAGTTGTTGGCCCAGCAAGGACTGACCAGATTAGATAATTTTGCTCTGACACTGACGGTTCTCTTTATCATC
ATGCCCAATTTTCTTCTGACAGCAGGCGGTGTCTTGTCCTGCGCCTATGCCTTTTTGATTTCTATGATGGATTTTGAAAA
GTTACCGCCGATTCGTAAGCTTTTAGCGGAAAGTCTGACTATTTCGTTGGGGATTTTGCCTATACTGATTTACTATTTTT
CTGAATTTCAGCCTTGGTCCGTAATTTTAACTTTTTTATTTTCACTACTCTTTGACCTACTGATGCTGCCAGGCTTAACC
CTCATTTTTATTTTGTCGCCACTTTTAAAAATCACTCAAGTCAATTTTTTCTTTGAGTTACTAGAAGATGTGATTCGTTG
GGTAGCTGACTTTGCTCCGCGCCCTTTGATTTTTGGGAAGCCCAACCTCTGGTTACTGGCCACTCTGCTTTTGGTTTTGG
CTTTAATCTATGACTTTCGGAGAAAGAAAAGCTGGCTTCTATCTTTTAGTTTACTTACTCTTCTCTTATTTTTTCTAACA
AAGCATCCGCTACAAAATGAGATTACAGTAGTGGATATTGGTCAGGGAGATAGCATTTTTCTCAGGGACTGGCAGGGCAG
GACGATTTTGATTGATGTAGGAGGACGAGTCGAGATAGGAAAGAAGGAGGCTTGGCAGGAGCGACAGACTTCATCCAATG
CAGAAAAGACCTTGATTCCCTATCTCAAAAGTCGTGGTGTTGGTAGTCTGGATGTATTGGTCCTGACTCATACCGATACC
GACCACATGGGCGATATGCTGGAGGTAGCCCAACATTTTTCCATCAAGGAAATCTATGTTTCTAAAGGAAGTCTGACTCA
GCCTGATTTTGTTCAAAAGCTGGAGCAGATAGAAAGTTCTGTCCATGTCGTAGAAGTGGGAGATGAGATTCCGGTATTTG
ACTCAGCTTTGCAGGTTCTCTATCCTAGTGGGACAGGCGACGGTGGAAATGATGATTCGATTGTACTCTACGGGGAGTTC
TTTCAGACAAAATTTTTGTTTACAGGTGATTTGGAAAGGCAGGGAGAAACTGAACTGCTGCAGCGATTTCCTCAGCTGAA
AGCAGATGTCTTAAAAGCAGGGCATCATGGCTCTAAAGGCTCTTCCAGTCCAGAGTTTTTAGAGCAAATTCAGCCGAAAC
TGGCCTTGATATCAGCCGGTCAGAATAATCGTTATCGACATCCGCATCAGGAAACTTTGCAAAGATTTGAGAAATTTAAT
ACTGCTATCTATCGAACTGACCAGCAGGGGGCCATTCGTTTGATTGGTTGGAATTCCTGGAGGATTGAAACGGTACGCTG
A

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

57.564

100

0.576
  comEC/celB Streptococcus mitis NCTC 12261

56.971

100

0.57
  comEC/celB Streptococcus pneumoniae TIGR4

56.627

100

0.567
  comEC/celB Streptococcus pneumoniae Rx1

55.957

100

0.56
  comEC/celB Streptococcus pneumoniae D39

55.957

100

0.56
  comEC/celB Streptococcus pneumoniae R6

55.957

100

0.56
  comEC Lactococcus lactis subsp. cremoris KW2

48.663

100

0.488

Multiple sequence alignment