Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQM75_RS09390 Genome accession   NZ_LS483380
Coordinates   1964512..1965783 (-) Length   423 a.a.
NCBI ID   WP_111692840.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1959512..1970783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS09365 (NCTC11824_01882) - 1961402..1961701 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  DQM75_RS09370 (NCTC11824_01883) ruvX 1961711..1962130 (-) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  DQM75_RS09375 (NCTC11824_01884) - 1962127..1962396 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  DQM75_RS09380 (NCTC11824_01885) spx 1962508..1962906 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  DQM75_RS09385 (NCTC11824_01886) recA 1963282..1964418 (-) 1137 WP_012678688.1 recombinase RecA Machinery gene
  DQM75_RS09390 (NCTC11824_01887) cinA 1964512..1965783 (-) 1272 WP_111692840.1 competence/damage-inducible protein A Machinery gene
  DQM75_RS09395 (NCTC11824_01888) - 1966469..1966759 (-) 291 WP_012516443.1 hypothetical protein -
  DQM75_RS09400 (NCTC11824_01889) - 1966753..1967325 (-) 573 WP_111692841.1 phospholipase -
  DQM75_RS09405 (NCTC11824_01890) - 1967622..1968467 (+) 846 WP_111692842.1 helix-turn-helix domain-containing protein -
  DQM75_RS09410 (NCTC11824_01891) - 1968904..1969455 (-) 552 WP_021321223.1 DNA-3-methyladenine glycosylase I -
  DQM75_RS09415 (NCTC11824_01892) ruvA 1969465..1970061 (-) 597 WP_012678694.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45890.67 Da        Isoelectric Point: 6.5148

>NTDB_id=1139365 DQM75_RS09390 WP_111692840.1 1964512..1965783(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTEDDLTKQT
LAKYLRKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIAALYAFNMVRKTLLKAENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1139365 DQM75_RS09390 WP_111692840.1 1964512..1965783(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGAAAGCTGAACTCATTGCAGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTCTATCGGA
AAAAATGGCAGAGCTTGGCATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGCTTGCTTTCTGTTATTG
ATATTGCTAGCCAGAGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGAGGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTAAGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAAGCTGCTAGGACACCAAATAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCACGCCAGTCTATACTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCCACCATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAGGCTC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGCATTCCATTGGTTGAGCTACAAAGGCATGGTGTTGTGAGCTCTTTCACAGCTGAGCAAATGGCTGCGCAGGCACG
CTGCTTGACCAATTCGGATATCGGTATTGGTCTAACAGGTGTTGCTGGCCCAGAGGCACTTGAGGGACAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTTATAGGAGGCCGTAGCCGTTTGGACGTG
CGGTATATTGCTGCCCTATATGCTTTTAATATGGTTCGTAAAACTTTATTAAAAGCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.922

100

0.709
  cinA Streptococcus mitis NCTC 12261

70.264

98.582

0.693
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

53.938

99.054

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

47.608

98.818

0.47

Multiple sequence alignment