Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQM54_RS10225 Genome accession   NZ_LS483375
Coordinates   2064713..2065969 (-) Length   418 a.a.
NCBI ID   WP_172455856.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2059713..2070969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS10195 (NCTC3165_02029) - 2061171..2061482 (-) 312 WP_008809966.1 DUF1292 domain-containing protein -
  DQM54_RS10200 (NCTC3165_02030) ruvX 2061503..2061922 (-) 420 WP_012131012.1 Holliday junction resolvase RuvX -
  DQM54_RS10205 (NCTC3165_02031) - 2061922..2062188 (-) 267 WP_008809968.1 IreB family regulatory phosphoprotein -
  DQM54_RS10210 (NCTC3165_02032) - 2062300..2062872 (-) 573 WP_061585388.1 SP0191 family lipoprotein -
  DQM54_RS10215 (NCTC3165_02033) spx 2063018..2063416 (-) 399 WP_008809970.1 transcriptional regulator Spx -
  DQM54_RS10220 (NCTC3165_02034) recA 2063503..2064654 (-) 1152 WP_008809971.1 recombinase RecA Machinery gene
  DQM54_RS10225 (NCTC3165_02035) cinA 2064713..2065969 (-) 1257 WP_172455856.1 competence/damage-inducible protein A Machinery gene
  DQM54_RS10235 (NCTC3165_02036) - 2066237..2066647 (+) 411 WP_111724227.1 helix-turn-helix domain-containing protein -
  DQM54_RS10240 (NCTC3165_02037) - 2066698..2067357 (-) 660 WP_111724228.1 CPBP family intramembrane glutamic endopeptidase -
  DQM54_RS10245 (NCTC3165_02038) - 2067362..2067916 (-) 555 WP_111724229.1 DNA-3-methyladenine glycosylase I -
  DQM54_RS10250 (NCTC3165_02039) ruvA 2067926..2068519 (-) 594 WP_111724230.1 Holliday junction branch migration protein RuvA -
  DQM54_RS10255 (NCTC3165_02040) - 2068687..2069190 (+) 504 WP_111724322.1 helix-turn-helix domain-containing protein -
  DQM54_RS10260 - 2069174..2069695 (+) 522 Protein_1968 RDD family protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44756.00 Da        Isoelectric Point: 4.7661

>NTDB_id=1139158 DQM54_RS10225 WP_172455856.1 2064713..2065969(-) (cinA) [Streptococcus gordonii strain NCTC3165]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELSFDPDAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLLEAGGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIEQQSDPTIAPYAKTGEVTLRLSTKALSQVEADTKFEAVEKEI
LAHKTFEEQPLSEVFYGYGDDNSLAQVAFELLKSQGKTISAAESLTAGLFQATLADFAGASSIFSGGFVTYSMEEKSRML
DIPLGVLEKHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEDHPAGTVFIGLASAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1139158 DQM54_RS10225 WP_172455856.1 2064713..2065969(-) (cinA) [Streptococcus gordonii strain NCTC3165]
ATGAAAGCAGAAATTATTGCTGTGGGCACCGAGATTCTGACAGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
GAAACTGGCTAGTCTGGGGATTGATGTCTATTTTCAGACAGCTGTAGGGGACAATGAAAATCGTCTCCTCTCTATCCTAG
AGATTGCAAAAGGACGTAGTAATCTAATTATCTTGACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTTTTAGGTCGAGAGTTGAGTTTTGACCCTGATGCTGTGGAAAAGCTGGATCGCTTTTTTGCTAGTCGACC
GGATTATGCCCGAACGCCCAACAATGAGCGTCAGGCCCAGCTGGTCGAAGGCTCGACTCCTTTACCAAATGCGACCGGCT
TAGCTGTCGGAGGATTGTTAGAAGCAGGCGGAGTGACCTATGTAGTCCTGCCTGGCCCGCCTAGTGAGCTTAAGCCTATG
GTCAATAATGAGCTGGTTCCCCTCTTATCCACAGGTCAGAAATTGTACTCACGGGTGCTGCGTTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGAGCAGCAGAGTGACCCCACCATTGCTCCTTATGCAAAGACAGGGG
AAGTTACCCTGCGACTGTCCACTAAGGCTCTGAGTCAGGTAGAAGCTGACACCAAGTTTGAGGCTGTGGAAAAGGAAATT
TTGGCACATAAGACTTTTGAGGAACAGCCCTTGTCAGAGGTTTTCTATGGTTATGGGGATGACAATTCCTTGGCACAGGT
GGCTTTTGAGTTGCTGAAGAGTCAAGGGAAGACGATTTCGGCGGCGGAGAGTCTGACAGCTGGCCTCTTTCAAGCGACCT
TGGCAGATTTTGCTGGAGCCTCTTCCATTTTTTCAGGTGGCTTTGTCACCTACAGCATGGAGGAAAAGAGCCGGATGCTG
GATATTCCGTTGGGAGTCTTGGAGAAGCATGGAGTTGTTTCAGCTTTTACGGCAGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTGGCTGTCAGTCTGACAGGTGTGGCTGGACCAGATTCACTAGAAGATCATCCAGCTGGAACTG
TTTTTATTGGCTTGGCTAGTGCTGCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGTAGCCGGCGAGATGTACGA
AAAATCGCTGTTCTGCACGCCTTTAACCTAGTGCGAAAGACTTTATTAAATAGTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

77.458

99.761

0.773
  cinA Streptococcus mitis NCTC 12261

76.978

99.761

0.768
  cinA Streptococcus pneumoniae TIGR4

76.499

99.761

0.763
  cinA Streptococcus pneumoniae Rx1

76.499

99.761

0.763
  cinA Streptococcus pneumoniae R6

76.499

99.761

0.763
  cinA Streptococcus pneumoniae D39

76.259

99.761

0.761
  cinA Streptococcus mutans UA159

74.402

100

0.744
  cinA Streptococcus suis isolate S10

54.327

99.522

0.541
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

100

0.464

Multiple sequence alignment