Detailed information NTG1138679

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: DQM55_RS08150
• Genome accession: NZ_LS483364
• Coordinates: 1646370..1647050 (-)
• Length: 226 a.a.
• NCBI ID: WP_111676100.1
• Uniprot ID: A0A2X3YRX6
• Organism: Streptococcus sanguinis strain NCTC11086
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1641370..1652050

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM55_RS08135 (NCTC11086_01668)	holA	1641739..1642785 (-)	1047	WP_111676095.1	DNA polymerase III subunit delta	-
DQM55_RS08140 (NCTC11086_01669)	-	1642975..1644021 (-)	1047	WP_111676097.1	DUF805 domain-containing protein	-
DQM55_RS08145 (NCTC11086_01670)	comEC/celB	1644146..1646386 (-)	2241	WP_111676099.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQM55_RS08150 (NCTC11086_01671)	comEA/celA/cilE	1646370..1647050 (-)	681	WP_111676100.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQM55_RS08155 (NCTC11086_01672)	-	1647196..1647744 (-)	549	WP_172454787.1	HXXEE domain-containing protein	-
DQM55_RS08160 (NCTC11086_01673)	-	1647817..1648557 (-)	741	WP_002900842.1	lysophospholipid acyltransferase family protein	-
DQM55_RS08165 (NCTC11086_01674)	-	1648715..1651054 (+)	2340	WP_111676104.1	cation-translocating P-type ATPase	-
DQM55_RS08170 (NCTC11086_01675)	-	1651185..1651931 (+)	747	WP_111676106.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-

Sequence

Protein

• Length: 226 a.a.
• Molecular weight: 23901.69 Da
• Isoelectric Point: 4.7365

>NTDB_id=1138679 DQM55_RS08150 WP_111676100.1 1646370..1647050(-) (comEA/celA/cilE) [Streptococcus sanguinis strain NCTC11086]
MLEEIIEKLKEYKLFVGLAVVGAVLGGFFLIKGNHQPQNQVAALSQEVTSSSSSADEESEKIVSKAKADEEESEQITVDI
KGAVKNPGVYELRAGARVHEAIQKAGGLTADAEAKSINQAQKLTDEAVIYVAKIGEEGADVTQTGQRQAGASDSAGASGG
KSDKVNLNTATEAELQTISGIGQKRASDIIAYRESSGRFKSVDDLKKVSGIGDKTLEKLKEYVTVD

Nucleotide

• Length: 681 bp

>NTDB_id=1138679 DQM55_RS08150 WP_111676100.1 1646370..1647050(-) (comEA/celA/cilE) [Streptococcus sanguinis strain NCTC11086]
ATGCTTGAAGAAATCATTGAGAAGCTTAAAGAATACAAGCTCTTTGTCGGTCTGGCAGTGGTTGGCGCTGTGCTAGGTGG
CTTTTTCCTCATCAAAGGAAATCATCAACCGCAAAACCAGGTAGCCGCCTTAAGTCAAGAGGTAACTTCCTCATCCAGCT
CAGCTGATGAAGAAAGCGAAAAGATTGTCTCTAAGGCCAAGGCGGACGAAGAGGAAAGCGAGCAGATTACTGTGGATATT
AAGGGAGCAGTCAAGAATCCTGGTGTCTATGAGCTGAGAGCAGGAGCGAGAGTCCATGAAGCCATCCAAAAAGCTGGCGG
ATTGACAGCAGACGCCGAGGCTAAGTCCATCAATCAGGCACAAAAATTAACGGATGAAGCAGTAATCTATGTGGCAAAGA
TTGGTGAAGAAGGAGCTGATGTCACCCAGACTGGCCAGCGTCAAGCAGGAGCTTCTGATTCTGCTGGTGCCAGTGGTGGA
AAGTCGGACAAGGTCAATCTAAATACGGCGACAGAGGCTGAACTGCAGACTATTTCAGGCATCGGACAGAAGCGGGCTTC
TGACATTATCGCCTACCGCGAAAGCAGTGGCCGCTTTAAGTCAGTAGATGATCTGAAAAAGGTGTCAGGTATTGGAGATA
AGACCTTAGAAAAGCTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (162-224)

• SLBB domain (SLBB) (78-131)

3D structure

• AlphaFold DB: A0A2X3YRX6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	50.431	100	0.518
comEA/celA/cilE	Streptococcus pneumoniae D39	50.431	100	0.518
comEA/celA/cilE	Streptococcus pneumoniae R6	50.431	100	0.518
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	51.327	100	0.513
comEA	Streptococcus thermophilus LMD-9	49.569	100	0.509
comEA/celA/cilE	Streptococcus mitis NCTC 12261	50.222	99.558	0.5
comEA/celA/cilE	Streptococcus mitis SK321	48.276	100	0.496
comEA	Bacillus subtilis subsp. subtilis str. 168	43.439	97.788	0.425
comEA	Lactococcus lactis subsp. cremoris KW2	41.778	99.558	0.416
comEA	Latilactobacillus sakei subsp. sakei 23K	34.855	100	0.372