Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DQM55_RS08145 Genome accession   NZ_LS483364
Coordinates   1644146..1646386 (-) Length   746 a.a.
NCBI ID   WP_111676099.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11086     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1639146..1651386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM55_RS08125 (NCTC11086_01666) - 1639856..1640935 (-) 1080 WP_009659969.1 serine hydrolase -
  DQM55_RS08130 (NCTC11086_01667) sodA 1641071..1641676 (-) 606 WP_009659917.1 superoxide dismutase SodA -
  DQM55_RS08135 (NCTC11086_01668) holA 1641739..1642785 (-) 1047 WP_111676095.1 DNA polymerase III subunit delta -
  DQM55_RS08140 (NCTC11086_01669) - 1642975..1644021 (-) 1047 WP_111676097.1 DUF805 domain-containing protein -
  DQM55_RS08145 (NCTC11086_01670) comEC/celB 1644146..1646386 (-) 2241 WP_111676099.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQM55_RS08150 (NCTC11086_01671) comEA/celA/cilE 1646370..1647050 (-) 681 WP_111676100.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQM55_RS08155 (NCTC11086_01672) - 1647196..1647744 (-) 549 WP_172454787.1 HXXEE domain-containing protein -
  DQM55_RS08160 (NCTC11086_01673) - 1647817..1648557 (-) 741 WP_002900842.1 lysophospholipid acyltransferase family protein -
  DQM55_RS08165 (NCTC11086_01674) - 1648715..1651054 (+) 2340 WP_111676104.1 cation-translocating P-type ATPase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 85163.31 Da        Isoelectric Point: 9.1507

>NTDB_id=1138678 DQM55_RS08145 WP_111676099.1 1644146..1646386(-) (comEC/celB) [Streptococcus sanguinis strain NCTC11086]
MSQWIKKLPLTPIYLAFILVWAYFAVYSGSSLAYFGLGVLLLRLFFSYPLKKSLAALAFLSLFVFFFLLRREMAEQAFRQ
EAPSTSSVQVLPDTIKVNGDSLSFRGRTNGRLYQVFYKIKSASEKEDFQQLTDLVVLDIEGEFEQAQQQRNFSGFDYQAY
LKSQGIYRILKINKIKSLRPISSLNPLDWLSVWRRKALVYIRSNFPSPMSHYMTGLLFGDLDTEFAEMSNLYSSLGIIHL
FALSGMQVGFFLDGFRRILLRLGMKRETVNALQLPFSFIYAGLTGFSVSVVRSLVQKLLAQQGLTRLDNFALTLMVLFII
MPNFLLTAGGVLSCAYAFLISMMDFEKLSPFRKLLAESLTISLGILPILIYYFSEFQPWSVILTFLFSLLFDLLMLPGLT
LIFILSPLLKITQVNFFFELLEDVIRWVADFAPRPLIFGKPNLWLLFALLLVLALIYDFRRKKSWLLSFSLLALLLFFLT
KHPLQNEITVVDIGQGDSIFLRDWRGRTVLIDVGGRVEIGKKEAWQERQTSSNAEKTLIPYLKSRGVASLDVLVLTHTDT
DHMGDMLEVAKHFSIKEIYVSKGSLTQLDFVQKLEQIETSVHVVEVGDEIPVFDSVLQVLYPSGTGDGGNDDSIVLYGEF
FQTKFLFTGDLERQGETELLQRFPQLKADVLKAGHHGSKGSSSPEFLEQIQPKLALISAGQNNRYRHPHQETLQRFEKFN
TAIYRTDQQGAIRLTGWNSWRIETVH

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=1138678 DQM55_RS08145 WP_111676099.1 1644146..1646386(-) (comEC/celB) [Streptococcus sanguinis strain NCTC11086]
ATGTCACAGTGGATTAAAAAGTTACCCCTCACCCCTATCTATCTGGCTTTCATCCTTGTATGGGCCTATTTTGCAGTCTA
TTCTGGAAGTTCTTTGGCTTATTTTGGGCTGGGTGTCCTTCTGCTTCGTCTCTTTTTCAGCTATCCCCTCAAAAAAAGTC
TAGCTGCTTTGGCATTCCTGTCCCTTTTTGTCTTCTTTTTCTTGCTTCGTCGGGAAATGGCAGAGCAGGCCTTTAGGCAG
GAAGCTCCGTCAACTAGCTCGGTTCAGGTCTTGCCAGATACGATCAAAGTCAATGGAGACTCCCTATCCTTTCGAGGGCG
AACCAACGGTCGACTTTATCAGGTCTTCTACAAGATCAAATCAGCCAGTGAAAAGGAAGATTTTCAGCAACTGACAGATT
TGGTCGTACTTGATATTGAAGGAGAGTTTGAACAGGCTCAGCAGCAACGAAATTTTTCGGGCTTTGACTATCAGGCTTAT
TTAAAGAGTCAGGGGATTTACCGTATCTTAAAAATCAATAAGATTAAGTCACTAAGACCAATTTCCAGCCTGAATCCACT
GGATTGGCTGTCTGTTTGGCGGAGAAAAGCGCTGGTCTATATTCGAAGTAATTTTCCCAGCCCGATGAGTCATTATATGA
CTGGACTCTTGTTTGGTGACCTGGATACGGAGTTTGCGGAAATGAGCAATCTGTATTCTAGCTTGGGTATCATCCACTTG
TTTGCCTTGTCTGGTATGCAGGTAGGTTTCTTTTTGGATGGTTTTCGCAGGATTCTTCTACGTTTGGGGATGAAGAGGGA
GACAGTAAACGCCTTGCAGCTGCCTTTTTCATTTATCTACGCTGGACTGACAGGCTTTTCTGTTTCTGTTGTCAGAAGCT
TAGTTCAGAAGTTATTGGCCCAGCAAGGATTGACCAGACTTGATAATTTTGCCCTGACACTGATGGTTCTCTTTATCATC
ATGCCCAATTTTCTTCTGACAGCTGGCGGTGTCTTATCCTGTGCTTATGCTTTTTTGATTTCTATGATGGATTTTGAGAA
GTTGTCGCCGTTTCGGAAGCTTTTAGCGGAAAGTCTGACTATTTCATTGGGGATTTTGCCTATACTAATCTACTATTTTT
CTGAATTTCAGCCTTGGTCCGTGATTTTAACTTTTCTATTTTCACTACTCTTTGATCTGCTGATGCTGCCAGGCTTAACC
CTCATTTTTATTTTGTCGCCACTTTTAAAAATCACTCAAGTCAATTTTTTCTTTGAGTTACTAGAAGATGTGATTCGTTG
GGTAGCTGATTTTGCTCCGCGCCCTTTGATTTTTGGAAAGCCCAACCTCTGGTTACTGTTCGCTCTGCTTTTGGTTTTGG
CTTTAATCTATGACTTTCGGAGAAAGAAAAGCTGGCTTTTATCTTTTAGTTTGCTAGCTCTTCTCTTATTTTTCCTAACA
AAGCATCCGCTGCAAAACGAGATCACAGTAGTGGATATTGGTCAGGGAGATAGCATTTTTCTCAGGGACTGGCGAGGCAG
GACGGTTTTGATTGATGTAGGAGGACGAGTCGAGATAGGAAAGAAAGAGGCTTGGCAGGAGCGACAGACTTCATCCAATG
CAGAAAAGACCTTAATTCCCTATCTCAAAAGTCGTGGCGTTGCTAGTCTGGATGTATTGGTCCTGACTCATACCGATACC
GATCACATGGGAGATATGCTGGAGGTAGCTAAGCATTTTTCCATCAAGGAAATCTATGTTTCTAAAGGAAGTCTGACTCA
GCTTGATTTTGTTCAAAAACTGGAGCAGATAGAAACTTCTGTCCATGTCGTAGAAGTAGGAGATGAGATTCCGGTATTTG
ACTCAGTTTTGCAGGTTCTCTATCCTAGCGGAACAGGAGACGGTGGAAATGATGATTCAATTGTACTCTACGGGGAGTTC
TTTCAGACAAAATTTTTGTTTACAGGTGATTTGGAAAGACAAGGAGAAACCGAACTGCTGCAGCGCTTCCCTCAGCTGAA
AGCGGATGTCTTAAAAGCAGGGCACCATGGTTCCAAAGGCTCGTCCAGTCCAGAGTTTTTAGAGCAAATTCAGCCGAAAC
TGGCCTTGATATCAGCCGGTCAGAATAATCGTTATCGTCATCCGCATCAGGAAACTTTGCAAAGATTTGAGAAGTTTAAT
ACAGCCATCTATCGAACTGACCAGCAGGGGGCCATTCGGTTGACTGGTTGGAATTCCTGGAGGATTGAAACAGTTCATTG
A

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

57.831

100

0.579
  comEC/celB Streptococcus mitis NCTC 12261

57.507

100

0.575
  comEC/celB Streptococcus pneumoniae TIGR4

57.162

100

0.572
  comEC/celB Streptococcus pneumoniae Rx1

56.359

100

0.564
  comEC/celB Streptococcus pneumoniae D39

56.359

100

0.564
  comEC/celB Streptococcus pneumoniae R6

56.359

100

0.564
  comEC Lactococcus lactis subsp. cremoris KW2

48.461

100

0.485

Multiple sequence alignment