Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   DQL37_RS00775 Genome accession   NZ_LS483352
Coordinates   117066..117392 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12052     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 112066..122392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL37_RS00760 (NCTC12052_00154) - 114698..115063 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL37_RS00765 (NCTC12052_00155) comYA 115156..116094 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL37_RS00770 (NCTC12052_00156) comYB 116030..117064 (+) 1035 WP_225793059.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL37_RS00775 (NCTC12052_00157) comYC 117066..117392 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL37_RS00780 (NCTC12052_00158) comGD 117367..117795 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD -
  DQL37_RS00785 (NCTC12052_00159) comGE 117752..118036 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  DQL37_RS00790 (NCTC12052_00160) comYF 118029..118463 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL37_RS00795 (NCTC12052_00161) comGG 118447..118773 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  DQL37_RS00800 (NCTC12052_00162) comYH 118871..119824 (+) 954 WP_023610092.1 class I SAM-dependent methyltransferase Machinery gene
  DQL37_RS00805 (NCTC12052_00163) - 119883..121079 (+) 1197 WP_002992742.1 acetate kinase -
  DQL37_RS00810 - 121266..121574 (+) 309 WP_032467031.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=1138023 DQL37_RS00775 WP_002986552.1 117066..117392(+) (comYC) [Streptococcus pyogenes strain NCTC12052]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1138023 DQL37_RS00775 WP_002986552.1 117066..117392(+) (comYC) [Streptococcus pyogenes strain NCTC12052]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment