Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL21_RS09255 Genome accession   NZ_LS483343
Coordinates   1806669..1807925 (-) Length   418 a.a.
NCBI ID   WP_018030469.1    Uniprot ID   -
Organism   Streptococcus ferus strain NCTC12278     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1801669..1812925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS09210 (NCTC12278_01851) - 1801678..1801977 (-) 300 WP_018030478.1 DUF1292 domain-containing protein -
  DQL21_RS09215 (NCTC12278_01852) ruvX 1801987..1802406 (-) 420 WP_018030477.1 Holliday junction resolvase RuvX -
  DQL21_RS09220 (NCTC12278_01853) - 1802403..1802672 (-) 270 WP_018030476.1 IreB family regulatory phosphoprotein -
  DQL21_RS09225 (NCTC12278_01854) - 1802845..1803303 (+) 459 WP_018030475.1 LytTR family DNA-binding domain-containing protein -
  DQL21_RS09230 (NCTC12278_01855) - 1803290..1803751 (+) 462 WP_018030474.1 DUF3021 domain-containing protein -
  DQL21_RS09235 (NCTC12278_01856) - 1803812..1804438 (-) 627 WP_018030473.1 SP0191 family lipoprotein -
  DQL21_RS09240 (NCTC12278_01857) - 1804456..1804884 (-) 429 WP_018030472.1 hypothetical protein -
  DQL21_RS09245 (NCTC12278_01858) spx 1804997..1805395 (-) 399 WP_018030471.1 transcriptional regulator Spx -
  DQL21_RS09250 (NCTC12278_01859) recA 1805477..1806628 (-) 1152 WP_018030470.1 recombinase RecA Machinery gene
  DQL21_RS09255 (NCTC12278_01860) cinA 1806669..1807925 (-) 1257 WP_018030469.1 competence/damage-inducible protein A Machinery gene
  DQL21_RS09260 (NCTC12278_01861) - 1808087..1808644 (-) 558 WP_018030468.1 DNA-3-methyladenine glycosylase I -
  DQL21_RS09265 (NCTC12278_01862) ruvA 1808673..1809263 (-) 591 WP_018030467.1 Holliday junction branch migration protein RuvA -
  DQL21_RS09270 (NCTC12278_01863) mutL 1809366..1811324 (-) 1959 WP_408641227.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44786.33 Da        Isoelectric Point: 4.8563

>NTDB_id=1137618 DQL21_RS09255 WP_018030469.1 1806669..1807925(-) (cinA) [Streptococcus ferus strain NCTC12278]
MKAELIAVGTEILTGQIVNTNAQFLSEKLAALGIDVYFQTAVGDNEARLQSVLEIAKSRSNLVILCGGLGPTEDDLTKQT
LAKFLGKPLVFDPLASQKLDDFFATRPQYARTPNNECQAQIIEGSLPIQNITGLAVGGLIESEGVTYVVLPGPPSELKPM
VNQHLLPLLTKDSTKLYSRVLRFFGIGESQLVTILSDLIEEQTDPTIAPYAKTGEVTLRLSTKAASQAAADDKLDQLETR
ILSRSPLEALFYAYGDETSLGEVVFDLLKRQGLTLSAAESLTAGLFQASLADFPGASQVFKGGFVTYSIEEKAKMLGIPL
QALEEQGVVSSFTAGRMAEQARLLTDSDLAVSLTGVAGPDSLEGHPAGTVFIGLATGRKTQTVKVQIGGRSRSDVRYIAV
LHAFNLVRKALLSKENLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1137618 DQL21_RS09255 WP_018030469.1 1806669..1807925(-) (cinA) [Streptococcus ferus strain NCTC12278]
ATGAAAGCAGAACTTATCGCGGTTGGAACAGAAATTTTAACAGGACAGATTGTCAATACCAATGCCCAGTTTTTATCAGA
AAAATTGGCGGCTTTGGGCATTGATGTCTATTTTCAGACAGCTGTTGGGGACAATGAAGCACGGTTGCAATCGGTTTTAG
AGATTGCTAAGAGCCGGAGTAATCTGGTGATACTTTGCGGCGGACTGGGACCGACAGAAGATGATTTGACAAAGCAGACT
CTGGCTAAATTTTTAGGAAAACCTTTGGTTTTTGACCCCCTGGCCAGCCAAAAACTGGACGATTTCTTTGCAACCAGACC
TCAATATGCAAGGACTCCTAATAATGAGTGTCAGGCTCAAATTATCGAAGGCTCTTTGCCCATCCAGAATATTACGGGTC
TGGCTGTCGGCGGACTGATTGAATCAGAAGGGGTAACCTACGTTGTACTGCCTGGGCCGCCAAGCGAACTTAAACCAATG
GTCAATCAACACTTGCTGCCGCTTCTTACGAAGGATTCAACCAAACTTTATTCGAGAGTCCTCCGCTTTTTTGGGATTGG
CGAAAGCCAGCTCGTGACGATATTAAGTGATCTTATTGAAGAGCAGACAGATCCTACCATTGCTCCCTATGCCAAAACAG
GGGAAGTCACTCTGCGTCTCTCGACCAAGGCTGCTAGCCAGGCAGCGGCTGATGATAAACTGGATCAATTAGAAACCCGT
ATTCTCAGTCGCAGCCCCTTAGAAGCTCTCTTTTATGCTTATGGAGATGAGACTTCTTTAGGGGAGGTTGTTTTTGACCT
TTTGAAGAGACAGGGGCTGACGCTGAGTGCTGCAGAAAGTCTGACAGCTGGCCTTTTTCAGGCAAGTTTGGCCGACTTTC
CTGGAGCTTCTCAGGTTTTCAAAGGCGGCTTTGTGACTTACAGCATAGAAGAAAAAGCTAAAATGTTGGGCATTCCCCTA
CAAGCGTTAGAGGAGCAGGGGGTAGTCAGCAGCTTTACAGCCGGAAGAATGGCCGAGCAGGCGCGCCTATTGACAGACTC
AGATTTAGCCGTTTCACTGACAGGTGTGGCAGGTCCTGACAGTTTAGAAGGTCATCCGGCGGGCACGGTTTTTATCGGGC
TAGCAACTGGTCGAAAAACTCAAACAGTCAAAGTTCAAATCGGTGGCAGAAGCCGGTCTGATGTGCGTTATATTGCGGTT
TTACACGCCTTTAATTTGGTACGCAAGGCTTTATTATCTAAGGAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.359

100

0.754
  cinA Streptococcus mitis NCTC 12261

75.12

100

0.751
  cinA Streptococcus mutans UA159

74.88

100

0.749
  cinA Streptococcus pneumoniae TIGR4

73.206

100

0.732
  cinA Streptococcus pneumoniae Rx1

72.967

100

0.73
  cinA Streptococcus pneumoniae R6

72.967

100

0.73
  cinA Streptococcus pneumoniae D39

72.727

100

0.727
  cinA Streptococcus suis isolate S10

55.718

98.325

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

47.356

99.522

0.471

Multiple sequence alignment