Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQL21_RS02950 Genome accession   NZ_LS483343
Coordinates   549428..550090 (+) Length   220 a.a.
NCBI ID   WP_018029438.1    Uniprot ID   A0A2X3VEB1
Organism   Streptococcus ferus strain NCTC12278     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 544428..555090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL21_RS02930 (NCTC12278_00569) - 544766..546388 (-) 1623 WP_018029434.1 malolactic enzyme -
  DQL21_RS02935 (NCTC12278_00570) - 546527..547423 (+) 897 WP_018029435.1 LysR family transcriptional regulator -
  DQL21_RS02940 (NCTC12278_00571) - 547447..548460 (-) 1014 WP_018029436.1 GIY-YIG nuclease family protein -
  DQL21_RS02945 (NCTC12278_00572) - 548598..549338 (+) 741 WP_018029437.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DQL21_RS02950 (NCTC12278_00573) comEA/celA/cilE 549428..550090 (+) 663 WP_018029438.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQL21_RS02955 (NCTC12278_00574) comEC/celB 550083..552314 (+) 2232 WP_018029439.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQL21_RS02960 (NCTC12278_00575) - 552456..553205 (+) 750 WP_018029440.1 DUF805 domain-containing protein -
  DQL21_RS02965 (NCTC12278_00576) - 553266..553865 (+) 600 WP_018029441.1 DUF805 domain-containing protein -
  DQL21_RS02970 (NCTC12278_00577) holA 553971..555008 (+) 1038 WP_018029442.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23631.54 Da        Isoelectric Point: 4.9666

>NTDB_id=1137589 DQL21_RS02950 WP_018029438.1 549428..550090(+) (comEA/celA/cilE) [Streptococcus ferus strain NCTC12278]
MLEDFIEKVKENKVTALLSLIIAGLLVSFHLLSQTPQPNKNQLPAIVSSGKKHSVSSVSQKETDKSPSSSGKITVDIKGA
VKKEGVYTLSSQSRLNDAVEVAGGFTAEADRKSVNLAQKLSDEAVIYVAFKGEDISVVGKPDNSQNANNSIDTEQSDKIN
LNTATLADLQTISGIGEKRAQDIIDYRDSNGGFSSLEDLKNISGIGDKTFEKLKDMVTIE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1137589 DQL21_RS02950 WP_018029438.1 549428..550090(+) (comEA/celA/cilE) [Streptococcus ferus strain NCTC12278]
ATGTTAGAAGATTTCATTGAAAAAGTTAAGGAAAATAAGGTGACAGCACTTTTATCGCTCATTATAGCAGGTCTTTTGGT
GAGCTTTCATCTCCTTTCTCAAACGCCCCAGCCAAATAAAAATCAGCTGCCAGCAATTGTTAGTTCTGGGAAGAAACATT
CGGTTTCGTCTGTCTCGCAGAAAGAGACAGACAAGAGTCCCTCTTCATCCGGCAAGATTACAGTGGACATTAAGGGAGCT
GTGAAAAAGGAAGGGGTCTATACCCTGTCGTCGCAAAGTCGTCTTAACGATGCGGTCGAAGTAGCGGGCGGTTTTACAGC
TGAAGCTGATCGTAAGTCTGTAAATCTAGCTCAAAAATTATCAGATGAGGCCGTTATCTATGTGGCTTTCAAAGGTGAAG
ACATCAGTGTTGTCGGAAAGCCTGATAACAGTCAGAACGCAAACAACAGCATAGATACGGAGCAGTCAGACAAAATCAAC
CTAAATACCGCCACCTTAGCCGATTTGCAGACCATTTCCGGTATCGGCGAGAAAAGGGCCCAAGATATTATTGACTATCG
GGACAGCAATGGTGGTTTCTCATCTTTAGAGGATTTAAAAAATATTTCAGGTATTGGGGATAAAACCTTTGAAAAATTAA
AGGACATGGTGACGATTGAGTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(75-128)

Helix-hairpin-helix motif (HHH_3)

(155-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VEB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae D39

47.534

100

0.482
  comEA/celA/cilE Streptococcus pneumoniae R6

47.534

100

0.482
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.534

100

0.482
  comEA/celA/cilE Streptococcus mitis SK321

46.667

100

0.477
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.637

100

0.473
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.222

100

0.473
  comEA Streptococcus thermophilus LMD-9

43.668

100

0.455
  comEA Lactococcus lactis subsp. cremoris KW2

41.704

100

0.423
  comEA Latilactobacillus sakei subsp. sakei 23K

34.568

100

0.382

Multiple sequence alignment