Detailed information NTG1137590

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQL21_RS02955
• Genome accession: NZ_LS483343
• Coordinates: 550083..552314 (+)
• Length: 743 a.a.
• NCBI ID: WP_018029439.1
• Uniprot ID: -
• Organism: Streptococcus ferus strain NCTC12278
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 545083..557314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL21_RS02935 (NCTC12278_00570)	-	546527..547423 (+)	897	WP_018029435.1	LysR family transcriptional regulator	-
DQL21_RS02940 (NCTC12278_00571)	-	547447..548460 (-)	1014	WP_018029436.1	GIY-YIG nuclease family protein	-
DQL21_RS02945 (NCTC12278_00572)	-	548598..549338 (+)	741	WP_018029437.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
DQL21_RS02950 (NCTC12278_00573)	comEA/celA/cilE	549428..550090 (+)	663	WP_018029438.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQL21_RS02955 (NCTC12278_00574)	comEC/celB	550083..552314 (+)	2232	WP_018029439.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQL21_RS02960 (NCTC12278_00575)	-	552456..553205 (+)	750	WP_018029440.1	DUF805 domain-containing protein	-
DQL21_RS02965 (NCTC12278_00576)	-	553266..553865 (+)	600	WP_018029441.1	DUF805 domain-containing protein	-
DQL21_RS02970 (NCTC12278_00577)	holA	553971..555008 (+)	1038	WP_018029442.1	DNA polymerase III subunit delta	-
DQL21_RS02975 (NCTC12278_00578)	sodA	555080..555685 (+)	606	WP_018029443.1	superoxide dismutase SodA	-
DQL21_RS02980 (NCTC12278_00579)	-	555959..556885 (+)	927	WP_408641235.1	serine hydrolase	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 83615.37 Da
• Isoelectric Point: 9.5871

>NTDB_id=1137590 DQL21_RS02955 WP_018029439.1 550083..552314(+) (comEC/celB) [Streptococcus ferus strain NCTC12278]
MSKFFPIQPIYLALLVVELYFLVVDFSVVTLVATLISCVLLLRQYSKPCLLKTILILCLFASYFLFVNWKSGRDYQAAPE
HLPAIHVIPDSISVNGDRLSFRGRYAQQSYQAFYRLKSETEKRYFQNLWQNTVIRGKIKLTEAEEQRNFKGFDYRAYLKT
QKIYRLAQIESIDAVEEAKALSLFDHLRSLRRRAIVHIQSKFPAPMAHYMTGLLFGYLDSSFDEMGELYSSLGIIHLFAL
SGMQVGFFLGKFRYLLLRLGIKQETVNGLQIPFSVLYAVLTGGSVSVIRSLLQSYLALFNIRKLDNLALSLMVMFFLVPH
FLATAGGVLSFAYAFILGLIDFEDLSGKRQLLAQTLAVYIGILPFLMWYFSSFQPVSILLTACLSFLFDVILLPLLSFLF
LLSPLIGLSLLNPFFQLLEDFISFLGHFFSRSLILGSPSVGLLLMLVIGLGLLYDFYKLKKARIILSIALCLLFFLVKNP
AYNEVTMVDVGQGDSIFLRDMKGKTLLIDVGGKPGFASSQTWQRAAETPNAERTLLPYLKSQGIGKIDQLVLTHTDTDHI
GDLEAVAKELDIGEILVSQGSLTVPEFRKRLKKLAAPVRVLQAGDKLPIMGSQLQVLYPSQVGDGGNNDSLVLYGSLLGL
RFLFTGDLEKEGEETLMAAYPKLPVDVLKAGHHGSKGSSSPAFLDFISPKLALISAGKNNRYRHPHQETLQRFERMQTLI
YRTDQMGAVRFKGIKQWQIEVVK

Nucleotide

• Length: 2232 bp

>NTDB_id=1137590 DQL21_RS02955 WP_018029439.1 550083..552314(+) (comEC/celB) [Streptococcus ferus strain NCTC12278]
TTGAGTAAGTTTTTTCCTATCCAACCGATTTATTTAGCACTCTTAGTCGTTGAACTTTATTTCTTAGTCGTTGACTTTTC
AGTAGTAACCTTAGTCGCAACCCTTATTTCTTGCGTGTTACTGCTACGGCAGTATTCTAAACCTTGTCTGCTTAAGACTA
TTCTGATTTTGTGTTTATTTGCGTCTTACTTTTTGTTTGTGAATTGGAAAAGTGGTAGAGATTATCAGGCGGCGCCAGAG
CATCTTCCAGCTATCCATGTCATTCCAGATAGTATTTCCGTCAATGGTGATCGCTTAAGCTTTCGTGGTCGATATGCGCA
GCAATCTTATCAGGCTTTCTATCGTTTGAAGTCAGAGACGGAGAAGCGCTATTTTCAAAATCTCTGGCAAAATACTGTGA
TAAGGGGAAAAATCAAGCTGACAGAGGCTGAGGAGCAGCGCAATTTCAAGGGCTTTGACTACCGGGCTTATCTTAAAACA
CAGAAGATTTACCGCTTGGCCCAAATCGAGTCTATTGATGCTGTAGAAGAAGCAAAAGCATTAAGCCTCTTTGATCACCT
GCGCAGTCTAAGGCGGCGGGCGATTGTGCATATACAAAGTAAGTTTCCTGCTCCAATGGCACACTACATGACCGGGCTCT
TATTCGGTTACTTGGATAGCAGTTTTGATGAGATGGGAGAGCTTTATTCCAGTTTAGGGATTATTCATCTTTTTGCCCTG
TCTGGGATGCAGGTGGGCTTTTTCTTGGGAAAGTTCCGTTACCTGCTCCTAAGATTAGGAATCAAACAGGAGACTGTTAA
TGGGCTGCAAATCCCGTTCTCAGTCCTCTATGCTGTTTTAACAGGTGGTTCTGTCTCTGTTATACGGAGTCTTTTACAGA
GTTATCTGGCTCTTTTTAATATTAGAAAACTGGATAATTTAGCCCTTTCTTTAATGGTCATGTTTTTCCTTGTCCCCCAT
TTTCTGGCAACGGCGGGCGGTGTTCTTAGTTTTGCTTATGCCTTTATTTTAGGCTTAATTGACTTTGAAGACCTGAGTGG
CAAGAGACAGCTGTTGGCTCAGACATTGGCTGTCTATATTGGAATCCTTCCTTTTTTGATGTGGTATTTTAGCTCTTTTC
AGCCGGTTTCCATTCTGCTGACAGCTTGTTTATCCTTTCTGTTTGATGTGATTCTTTTGCCGCTGCTGAGCTTTCTTTTT
CTCCTCTCTCCCTTGATTGGTCTCAGTCTATTGAATCCTTTTTTCCAGCTTTTAGAAGATTTTATTAGTTTTTTGGGGCA
TTTTTTTAGCCGCTCATTGATTTTGGGCAGCCCTTCAGTAGGTCTTTTGCTGATGCTCGTCATTGGCTTAGGCTTGCTTT
ATGATTTTTATAAATTAAAAAAAGCGAGGATAATCCTTTCCATTGCCCTGTGTCTTCTCTTTTTTCTCGTTAAAAATCCC
GCTTATAATGAAGTAACTATGGTCGATGTAGGCCAGGGGGACAGTATTTTCCTGAGGGACATGAAAGGAAAAACGCTTTT
GATTGATGTTGGCGGAAAGCCTGGGTTTGCCAGTTCACAAACTTGGCAGAGGGCAGCAGAGACACCCAATGCTGAAAGAA
CGCTGCTTCCTTACTTAAAAAGTCAGGGAATTGGTAAGATTGATCAGTTGGTGCTCACCCACACCGATACGGATCATATA
GGAGATTTGGAGGCTGTCGCTAAAGAGCTGGATATTGGTGAAATTTTGGTTAGTCAAGGGAGTCTGACGGTACCAGAGTT
TAGAAAACGTTTAAAGAAGCTGGCCGCACCTGTTAGGGTGCTTCAGGCAGGGGATAAATTGCCTATAATGGGGAGCCAGC
TGCAGGTTCTTTATCCCAGTCAAGTAGGAGATGGCGGTAATAATGACTCCCTCGTCTTATATGGCTCCTTGCTAGGCCTT
CGTTTTTTATTTACAGGAGATTTGGAGAAGGAAGGGGAGGAGACCCTGATGGCAGCTTATCCGAAACTTCCGGTTGATGT
TTTAAAAGCAGGCCATCACGGCAGCAAGGGCTCCTCAAGTCCAGCTTTTCTGGATTTTATCTCACCCAAGCTAGCCTTAA
TATCAGCAGGCAAGAATAATCGCTACCGGCATCCTCATCAGGAAACTCTGCAGCGTTTTGAAAGGATGCAGACCCTGATT
TATAGGACAGATCAAATGGGAGCTGTTCGCTTCAAGGGAATCAAGCAATGGCAGATAGAGGTTGTCAAGTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (213-454)

• Metallo-beta-lactamase superfamily (Lactamase_B) (489-697)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	50.74	100	0.507
comEC/celB	Streptococcus pneumoniae TIGR4	50.135	99.865	0.501
comEC/celB	Streptococcus mitis NCTC 12261	50.202	99.731	0.501
comEC/celB	Streptococcus pneumoniae D39	49.596	99.865	0.495
comEC/celB	Streptococcus pneumoniae Rx1	49.596	99.865	0.495
comEC/celB	Streptococcus pneumoniae R6	49.596	99.865	0.495
comEC	Lactococcus lactis subsp. cremoris KW2	47.855	100	0.48