Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL78_RS00410 Genome accession   NZ_LS483306
Coordinates   80925..82169 (+) Length   414 a.a.
NCBI ID   WP_016250399.1    Uniprot ID   S1R6J8
Organism   Enterococcus cecorum strain NCTC12421     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 75925..87169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL78_RS00390 (NCTC12421_00081) yfmF 76499..77764 (+) 1266 WP_016250403.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  DQL78_RS00395 (NCTC12421_00082) yfmH 77757..79046 (+) 1290 WP_016250402.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  DQL78_RS00400 (NCTC12421_00083) - 79233..80171 (+) 939 WP_016250401.1 helix-turn-helix domain-containing protein -
  DQL78_RS00405 (NCTC12421_00084) pgsA 80282..80860 (+) 579 WP_026209940.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  DQL78_RS00410 (NCTC12421_00085) cinA 80925..82169 (+) 1245 WP_016250399.1 competence/damage-inducible protein A Machinery gene
  DQL78_RS00415 (NCTC12421_00086) recA 82296..83342 (+) 1047 WP_016250398.1 recombinase RecA Machinery gene
  DQL78_RS00420 (NCTC12421_00087) rny 83560..85119 (+) 1560 WP_016250397.1 ribonuclease Y -
  DQL78_RS00425 (NCTC12421_00088) - 85337..85558 (+) 222 WP_016250396.1 helix-turn-helix transcriptional regulator -
  DQL78_RS00430 (NCTC12421_00089) - 85545..86306 (+) 762 WP_016250395.1 DUF3169 family protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45441.78 Da        Isoelectric Point: 4.7801

>NTDB_id=1135708 DQL78_RS00410 WP_016250399.1 80925..82169(+) (cinA) [Enterococcus cecorum strain NCTC12421]
MNAEIIAVGTEILMGQIVNSNAAYLSEQLANLGINVYYHVAVGDNEKRLTACLERAKSRSDLIVLCGGLGPTQDDLTKQT
VAKFVNQELVYDPTGHARLMDYFAKTKREMTENNLLQALTFKDGRGIANPNGLAVGIYYEDSDHTHYLLLPGPPRELKAM
FRQNVVPLLREINPQDTKLYSRVLRFYGIGESQLVTLLADFIDHQTNPTIAPYAKTNEVTLRLTANAPTQDEADVLLDEL
EEKIQALAGAYFYGYGDDFSLAEAMIAQLKEKNRTISVAESLTAGLFASTLGQYPGVSQVFKGGVVTYSLEMKAALLDID
ADYLREVGTVSEACVTLMAKNMQQKAQTDYAIAFSGVAGPDQLEGQAVGTVWMALATPNGVQTYCKQFPHGRNEIRQAAV
MFGLNLVYRALLAE

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=1135708 DQL78_RS00410 WP_016250399.1 80925..82169(+) (cinA) [Enterococcus cecorum strain NCTC12421]
ATGAATGCAGAAATCATTGCAGTCGGAACAGAGATTTTGATGGGGCAAATCGTGAATTCTAATGCCGCCTATCTTTCAGA
GCAATTAGCCAATTTGGGGATTAATGTTTATTATCATGTCGCAGTCGGAGATAATGAAAAGCGATTGACGGCCTGTCTTG
AACGTGCCAAAAGTCGGAGTGATTTAATCGTGCTTTGTGGTGGGTTGGGGCCTACGCAAGATGATTTAACCAAGCAAACC
GTAGCCAAATTTGTCAATCAAGAATTAGTCTATGATCCAACAGGGCATGCACGTTTGATGGATTATTTTGCCAAGACCAA
GCGCGAAATGACCGAAAATAATTTATTACAAGCCCTCACTTTTAAGGATGGTCGGGGTATTGCCAATCCAAATGGTCTAG
CGGTCGGTATTTATTATGAAGATAGCGATCATACCCACTATTTATTATTGCCTGGGCCACCGCGCGAGTTAAAGGCGATG
TTTCGTCAAAATGTTGTGCCACTTTTGCGTGAAATTAACCCACAAGATACGAAACTCTATTCTCGGGTGTTGCGTTTTTA
TGGGATTGGCGAATCGCAGTTAGTCACGCTTTTAGCTGATTTCATTGACCATCAGACTAACCCAACGATTGCTCCTTATG
CCAAAACCAATGAAGTAACGTTGCGCCTGACAGCCAATGCCCCTACCCAAGATGAAGCCGATGTGTTGCTGGATGAATTA
GAGGAGAAAATTCAAGCTTTGGCCGGTGCTTACTTTTATGGTTATGGCGATGATTTTTCGTTAGCGGAGGCGATGATTGC
GCAATTAAAAGAGAAAAATCGGACAATCAGTGTGGCTGAGAGTTTGACAGCCGGCCTTTTTGCTTCCACTTTAGGACAAT
ATCCGGGGGTGTCACAGGTCTTTAAAGGTGGTGTGGTTACTTATTCCCTTGAGATGAAGGCGGCCTTATTAGATATTGAT
GCCGATTATTTACGAGAAGTCGGGACGGTGAGTGAAGCTTGTGTCACCTTAATGGCTAAAAATATGCAGCAAAAAGCGCA
AACAGATTATGCCATTGCTTTTAGTGGCGTGGCAGGACCTGATCAATTAGAAGGCCAAGCAGTCGGAACGGTCTGGATGG
CTTTGGCGACACCAAATGGGGTACAGACTTATTGCAAACAGTTCCCCCATGGACGTAATGAAATTCGCCAAGCCGCTGTC
ATGTTTGGGTTAAATCTCGTTTATCGCGCGCTTTTAGCTGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(260-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S1R6J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.029

100

0.527
  cinA Streptococcus pneumoniae TIGR4

51.064

100

0.522
  cinA Streptococcus pneumoniae R6

50.827

100

0.519
  cinA Streptococcus mitis SK321

50.827

100

0.519
  cinA Streptococcus pneumoniae Rx1

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus mitis NCTC 12261

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

44.878

99.034

0.444
  cinA Streptococcus suis isolate S10

47.792

92.995

0.444

Multiple sequence alignment