Detailed information NTG0113209

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: SA268_RS00245
• Genome accession: NZ_CP006630
• Coordinates: 54953..56581 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186608.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus SA268
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	41660..63559	54953..56581	within	0

Gene organization within MGE regions

Location: 41660..63559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA268_RS00170 (SA268_0035)	ccrC	41660..43336 (+)	1677	WP_000676596.1	cassette chromosome recombinase CcrC	-
SA268_RS00175	-	43442..43780 (+)	339	WP_000171559.1	SAUGI family uracil-DNA glycosylase inhibitor	-
SA268_RS00180 (SA268_0036)	-	43876..44187 (+)	312	WP_001083109.1	DUF960 family protein	-
SA268_RS00185 (SA268_0037)	-	44203..44709 (+)	507	WP_000447786.1	DUF1643 domain-containing protein	-
SA268_RS00190 (SA268_0038)	-	44858..45532 (-)	675	WP_001105987.1	IS6-like element IS257 family transposase	-
SA268_RS14395	-	45568..45957 (+)	390	WP_020444595.1	hydroxymethylglutaryl-CoA synthase	-
SA268_RS00200 (SA268_0040)	-	46874..47617 (+)	744	WP_000958858.1	glycerophosphoryl diester phosphodiesterase	-
SA268_RS00205 (SA268_0041)	-	47714..48142 (+)	429	WP_000872606.1	MaoC family dehydratase	-
SA268_RS00210 (SA268_0042)	mecA	48188..50197 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
SA268_RS00215 (SA268_0043)	-	50294..51280 (+)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
SA268_RS00220 (SA268_0044)	-	51270..51512 (+)	243	Protein_41	type I restriction enzyme endonuclease domain-containing protein	-
SA268_RS00225 (SA268_0045)	-	51503..53113 (-)	1611	Protein_42	IS1182 family transposase	-
SA268_RS00230 (SA268_0046)	-	53162..53668 (-)	507	WP_001092189.1	DUF1643 domain-containing protein	-
SA268_RS00235 (SA268_0047)	-	53683..53994 (-)	312	WP_000700851.1	DUF960 family protein	-
SA268_RS00240	-	54081..54431 (-)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
SA268_RS00245 (SA268_0049)	ccrB	54953..56581 (-)	1629	WP_001186608.1	cassette chromosome recombinase CcrB	Machinery gene
SA268_RS00250 (SA268_0050)	ccrA	56603..57952 (-)	1350	WP_000815640.1	cassette chromosome recombinase CcrA	Machinery gene
SA268_RS00255 (SA268_0051)	cch1	58186..59973 (-)	1788	WP_000122620.1	cassette chromosome replicative helicase	-
SA268_RS00260 (SA268_0052)	ssb	59973..60263 (-)	291	WP_001036438.1	cassette chromosome ssDNA-binding protein	-
SA268_RS00265 (SA268_0053)	-	60402..61451 (+)	1050	WP_000613248.1	hypothetical protein	-
SA268_RS00270 (SA268_0054)	-	62069..63559 (+)	1491	WP_000554504.1	RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62654.83 Da
• Isoelectric Point: 9.7970

>NTDB_id=113209 SA268_RS00245 WP_001186608.1 54953..56581(-) (ccrB) [Staphylococcus aureus subsp. aureus SA268]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFECYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKINNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKTLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI

Nucleotide

• Length: 1629 bp

>NTDB_id=113209 SA268_RS00245 WP_001186608.1 54953..56581(-) (ccrB) [Staphylococcus aureus subsp. aureus SA268]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATCGACTGTGTTATG
GTATACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTGTCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAGATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAACGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTGCTATGCCAAAGGACATGGCTATCGTAAAATTGCCAATGCATTGAATCACAAAGGATATGTCACTAAAA
AGGGGAAACCTTTCAGTATTAGTTCAATCACATACATCTTAGCTAACCCTTTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTGAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAGAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACTCTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAAATAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGACTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATTAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTATTTT
TGCCCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (180-280)

• Resolvase, N terminal domain (Resolvase) (11-156)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	98.893	100	0.989