Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GPW69_RS00405 Genome accession   NZ_LR738724
Coordinates   66370..67551 (+) Length   393 a.a.
NCBI ID   WP_074391043.1    Uniprot ID   -
Organism   Streptococcus suis isolate 9401240     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 61370..72551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS00385 mutL 62590..64527 (+) 1938 WP_074391041.1 DNA mismatch repair endonuclease MutL -
  GPW69_RS00390 ruvA 64566..65156 (+) 591 WP_074391042.1 Holliday junction branch migration protein RuvA -
  GPW69_RS00400 - 65764..66333 (+) 570 WP_044692561.1 DNA-3-methyladenine glycosylase I -
  GPW69_RS00405 cinA 66370..67551 (+) 1182 WP_074391043.1 competence/damage-inducible protein A Machinery gene
  GPW69_RS00410 recA 67603..68754 (+) 1152 WP_024388019.1 recombinase RecA Machinery gene
  GPW69_RS00415 spx 68990..69388 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  GPW69_RS00420 - 69488..69754 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  GPW69_RS00425 ruvX 69754..70173 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  GPW69_RS00430 - 70185..70505 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  GPW69_RS10765 - 70676..70798 (+) 123 WP_257048998.1 hypothetical protein -
  GPW69_RS00435 rpsJ 71007..71315 (+) 309 WP_002939332.1 30S ribosomal protein S10 -
  GPW69_RS00440 rplC 71387..72013 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42952.00 Da        Isoelectric Point: 4.4970

>NTDB_id=1129575 GPW69_RS00405 WP_074391043.1 66370..67551(+) (cinA) [Streptococcus suis isolate 9401240]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQT
LATFLGRKLVFDEKAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAAGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKMVASCLIEKKQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISKKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=1129575 GPW69_RS00405 WP_074391043.1 66370..67551(+) (cinA) [Streptococcus suis isolate 9401240]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGCCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
AAAATGCGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAAGATGATTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAAATTGGTCTTTGATGAAAAGGCTATGGCAAAATTAGACCGCTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGCTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGCGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTGCCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGCATTGG
TGAAAGCCAGCTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCACCCTATGCTAAGGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGATAATAGTTTGGTCAAAATGGTAGCGTCTTG
TTTGATAGAGAAAAAACAAACTATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGTTTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGGGGGAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACCTTGGCTACGACCTCGGGTATTTCCAAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTTTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Competence-damaged protein (CinA)

(258-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.148

100

0.941
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

41.176

99.491

0.41

Multiple sequence alignment