Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FGL17_RS00755 Genome accession   NZ_LR594052
Coordinates   118192..119133 (+) Length   313 a.a.
NCBI ID   WP_093959143.1    Uniprot ID   A0A4V0H0H6
Organism   Streptococcus porcinus strain NCTC10924     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113192..124133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL17_RS00745 (NCTC10924_00152) rpoC 113985..117620 (+) 3636 WP_039984732.1 DNA-directed RNA polymerase subunit beta' -
  FGL17_RS00750 (NCTC10924_00153) - 117746..118111 (+) 366 WP_003085731.1 DUF1033 family protein -
  FGL17_RS00755 (NCTC10924_00154) comYA 118192..119133 (+) 942 WP_093959143.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL17_RS00760 (NCTC10924_00155) comYB 119015..120100 (+) 1086 WP_257846288.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL17_RS00765 (NCTC10924_00156) comYC 120100..120426 (+) 327 WP_003083111.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL17_RS00770 (NCTC10924_00157) comGD 120476..120814 (+) 339 WP_003085212.1 competence type IV pilus minor pilin ComGD -
  FGL17_RS00775 (NCTC10924_00158) comGE 120786..121079 (+) 294 WP_039984736.1 competence type IV pilus minor pilin ComGE -
  FGL17_RS00780 comGF 121099..121500 (+) 402 Protein_107 competence type IV pilus minor pilin ComGF -
  FGL17_RS00785 (NCTC10924_00159) comGG 121478..121876 (+) 399 WP_039984739.1 competence type IV pilus minor pilin ComGG -
  FGL17_RS00790 (NCTC10924_00160) comYH 121921..122877 (+) 957 WP_003084266.1 class I SAM-dependent methyltransferase Machinery gene
  FGL17_RS00795 (NCTC10924_00161) - 122933..124126 (+) 1194 WP_003085774.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35394.83 Da        Isoelectric Point: 7.8386

>NTDB_id=1128112 FGL17_RS00755 WP_093959143.1 118192..119133(+) (comYA) [Streptococcus porcinus strain NCTC10924]
MIQKTGEALVSQAVNLKAQDIYIIPYEKQYKVFMRVGDERRFIDNYDMKQMASLISHFKFVAGMNVGEKRRCQLGACDYK
GTLSESIPLRLSCVGNFRGFESLVIRLLTTVNKPLNYWFDTDQKVEKVISGRGLYLFSGPVGSGKTSLMYQLLTRIAKDK
QVITIEDPVEIQEDSLLQIQVNESIGMTYDNLIKLSLRHRPDYLIIGEIRDAETAKAVIRASLTGAVVFSTVHAKSIPGV
YKRLLELGIKSEEINHTLKFIAYQRLIAGGGLIDFAIETFETHSNQEWNQKLDHLLAEGHITQQQALSEKISD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1128112 FGL17_RS00755 WP_093959143.1 118192..119133(+) (comYA) [Streptococcus porcinus strain NCTC10924]
ATGATACAAAAAACAGGTGAAGCATTAGTTAGTCAAGCGGTAAATCTAAAGGCACAAGATATCTATATAATCCCTTATGA
AAAGCAGTATAAAGTTTTCATGAGAGTTGGAGATGAGAGGCGATTTATTGATAATTATGACATGAAACAGATGGCAAGTC
TTATTAGCCATTTTAAGTTTGTAGCAGGGATGAATGTAGGAGAAAAGAGACGCTGTCAACTTGGAGCCTGTGACTATAAG
GGAACTTTATCAGAATCCATTCCATTACGTCTTTCTTGTGTTGGGAATTTTAGAGGTTTTGAAAGTTTAGTTATCAGACT
CTTAACAACTGTTAATAAACCTCTCAATTACTGGTTTGATACTGATCAAAAAGTAGAAAAAGTTATTTCTGGAAGAGGTC
TTTATCTTTTCTCGGGTCCTGTAGGGTCGGGTAAAACGAGTCTCATGTATCAACTACTGACACGTATAGCAAAGGATAAA
CAAGTTATTACAATTGAAGATCCTGTTGAAATTCAAGAGGACAGCCTATTACAAATTCAAGTAAATGAAAGTATTGGAAT
GACTTATGATAACCTTATTAAACTTTCCCTCAGACATCGTCCAGATTATTTAATTATTGGAGAGATTCGTGATGCTGAGA
CTGCAAAAGCAGTCATTAGAGCAAGCTTAACAGGAGCTGTAGTCTTTTCTACTGTCCACGCAAAAAGTATTCCAGGAGTA
TATAAAAGATTGTTAGAACTAGGTATCAAAAGTGAAGAGATAAATCATACTCTAAAATTTATTGCGTACCAAAGGTTGAT
AGCAGGAGGAGGACTTATTGATTTTGCCATCGAGACATTCGAAACTCATTCCAATCAAGAATGGAATCAAAAACTTGATC
ACTTACTTGCAGAAGGACATATCACTCAACAACAGGCACTCTCGGAAAAAATTAGCGACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H0H6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

63.898

100

0.639
  comYA Streptococcus mutans UA140

63.898

100

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comYA Streptococcus gordonii str. Challis substr. CH1

60.064

100

0.601
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

58.013

99.681

0.578
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

57.692

99.681

0.575
  comGA/cglA/cilD Streptococcus pneumoniae D39

57.692

99.681

0.575
  comGA/cglA/cilD Streptococcus pneumoniae R6

57.692

99.681

0.575
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

57.692

99.681

0.575
  comGA Lactococcus lactis subsp. cremoris KW2

52.244

99.681

0.521

Multiple sequence alignment