Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FGL17_RS00760 Genome accession   NZ_LR594052
Coordinates   119015..120100 (+) Length   361 a.a.
NCBI ID   WP_257846288.1    Uniprot ID   -
Organism   Streptococcus porcinus strain NCTC10924     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 114015..125100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL17_RS00750 (NCTC10924_00153) - 117746..118111 (+) 366 WP_003085731.1 DUF1033 family protein -
  FGL17_RS00755 (NCTC10924_00154) comYA 118192..119133 (+) 942 WP_093959143.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL17_RS00760 (NCTC10924_00155) comYB 119015..120100 (+) 1086 WP_257846288.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL17_RS00765 (NCTC10924_00156) comYC 120100..120426 (+) 327 WP_003083111.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL17_RS00770 (NCTC10924_00157) comGD 120476..120814 (+) 339 WP_003085212.1 competence type IV pilus minor pilin ComGD -
  FGL17_RS00775 (NCTC10924_00158) comGE 120786..121079 (+) 294 WP_039984736.1 competence type IV pilus minor pilin ComGE -
  FGL17_RS00780 comGF 121099..121500 (+) 402 Protein_107 competence type IV pilus minor pilin ComGF -
  FGL17_RS00785 (NCTC10924_00159) comGG 121478..121876 (+) 399 WP_039984739.1 competence type IV pilus minor pilin ComGG -
  FGL17_RS00790 (NCTC10924_00160) comYH 121921..122877 (+) 957 WP_003084266.1 class I SAM-dependent methyltransferase Machinery gene
  FGL17_RS00795 (NCTC10924_00161) - 122933..124126 (+) 1194 WP_003085774.1 acetate kinase -
  FGL17_RS00800 (NCTC10924_00163) - 124391..124600 (+) 210 WP_093959144.1 helix-turn-helix transcriptional regulator -
  FGL17_RS00805 (NCTC10924_00164) - 124597..125049 (+) 453 WP_093959145.1 hypothetical protein -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 41613.70 Da        Isoelectric Point: 10.0333

>NTDB_id=1128113 FGL17_RS00760 WP_257846288.1 119015..120100(+) (comYB) [Streptococcus porcinus strain NCTC10924]
MPSRHSKLIPIKNGIKNLITYLQKDISLNNRHSRKKLATKKQAKLIQLLHNLSQSGFNLAEMIAFLEKTQILDRKHLSLM
KTDLLNGCSLSEMMRHLGFPDGIITQLSLAEAHGNTKKCLGKIEDYLVQTQKIRQKTIEVVTYPIILLTFLILIILGLRH
YLMPQMEKQSTLTYFLNNFPVYLLSLSIILLLTVIALVIRWRKLGKMKQMIQYSQIPLLAPFLKLYMTAFYAREWGNLIS
QGIELSQIVTIMSIEKSDLIKEIGLDMRQSFLEGQSFHEKVRGYPFFSDELSLMIEYGEIKGKLGQELDIYGQLTWDAYF
RKLFQATQIIQPFIFMIVALIIVMIYAAMLLPMYNTIGGTI

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=1128113 FGL17_RS00760 WP_257846288.1 119015..120100(+) (comYB) [Streptococcus porcinus strain NCTC10924]
TTGCCATCGAGACATTCGAAACTCATTCCAATCAAGAATGGAATCAAAAACTTGATCACTTACTTGCAGAAGGACATATC
ACTCAACAACAGGCACTCTCGGAAAAAATTAGCGACTAAAAAACAGGCCAAATTAATCCAACTCTTACATAATTTAAGTC
AAAGTGGTTTTAATCTAGCAGAGATGATCGCCTTCTTAGAAAAAACACAGATCTTAGACCGAAAACATCTTAGCTTGATG
AAGACTGATTTGTTAAATGGATGTAGTTTATCAGAAATGATGAGGCATTTAGGATTTCCTGATGGAATTATTACCCAACT
AAGTTTAGCTGAAGCTCATGGCAATACCAAAAAATGTTTGGGTAAAATTGAAGACTATCTAGTACAGACGCAAAAGATTA
GGCAAAAGACAATTGAAGTCGTGACCTATCCCATCATTCTCCTTACTTTTTTAATTTTAATCATCCTGGGCTTGAGACAT
TACTTAATGCCTCAGATGGAGAAACAAAGCACTTTGACCTATTTTCTCAATAATTTCCCAGTTTACCTCCTAAGTTTGTC
AATTATTCTTCTGCTTACGGTCATTGCTTTGGTGATCAGATGGCGTAAACTTGGAAAGATGAAACAGATGATACAATACA
GTCAGATTCCTTTGTTGGCACCCTTCCTAAAGCTCTATATGACGGCTTTTTATGCCCGTGAATGGGGGAATTTAATTAGT
CAAGGTATCGAACTGAGTCAAATAGTAACCATTATGAGTATTGAAAAATCTGATTTGATAAAAGAAATAGGTTTAGATAT
GAGACAATCATTTCTTGAAGGGCAGAGTTTCCACGAAAAAGTAAGGGGATATCCTTTTTTTAGTGATGAGTTGAGTTTGA
TGATTGAATATGGTGAAATCAAAGGGAAATTAGGTCAGGAGCTAGATATTTATGGCCAACTGACATGGGATGCTTATTTT
AGAAAACTCTTCCAAGCGACACAGATTATCCAACCTTTCATATTTATGATTGTCGCCCTGATTATTGTAATGATTTATGC
CGCTATGCTATTACCTATGTATAACACAATTGGAGGAACAATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(46-164)

Type II secretion system (T2SS), protein F (T2SSF)

(232-352)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

51.917

93.906

0.488
  comYB Streptococcus mutans UA159

51.622

93.906

0.485
  comGB/cglB Streptococcus mitis SK321

48.949

92.244

0.452
  comGB/cglB Streptococcus mitis NCTC 12261

48.649

92.244

0.449
  comGB/cglB Streptococcus pneumoniae Rx1

46.547

92.244

0.429
  comGB/cglB Streptococcus pneumoniae R6

46.547

92.244

0.429
  comGB/cglB Streptococcus pneumoniae TIGR4

46.547

92.244

0.429
  comGB/cglB Streptococcus pneumoniae D39

46.547

92.244

0.429
  comYB Streptococcus gordonii str. Challis substr. CH1

45.294

94.183

0.427
  comGB Lactococcus lactis subsp. cremoris KW2

42.69

94.737

0.404

Multiple sequence alignment