Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FGL12_RS08165 Genome accession   NZ_LR594041
Coordinates   1689072..1689737 (-) Length   221 a.a.
NCBI ID   WP_012130666.1    Uniprot ID   A8AYM0
Organism   Streptococcus gordonii strain NCTC9124     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1684072..1694737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS08150 (NCTC9124_01641) - 1685042..1685647 (-) 606 WP_012130663.1 Fe-Mn family superoxide dismutase -
  FGL12_RS08155 (NCTC9124_01642) holA 1685720..1686757 (-) 1038 WP_012130664.1 DNA polymerase III subunit delta -
  FGL12_RS08160 (NCTC9124_01643) comEC/celB 1686848..1689088 (-) 2241 WP_012130665.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FGL12_RS08165 (NCTC9124_01644) comEA/celA/cilE 1689072..1689737 (-) 666 WP_012130666.1 helix-hairpin-helix domain-containing protein Machinery gene
  FGL12_RS08170 (NCTC9124_01645) - 1689834..1690361 (-) 528 WP_138101303.1 HXXEE domain-containing protein -
  FGL12_RS08175 (NCTC9124_01646) - 1690400..1691140 (-) 741 WP_041789898.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FGL12_RS08180 (NCTC9124_01647) - 1691270..1693672 (+) 2403 WP_241974397.1 cation-translocating P-type ATPase -
  FGL12_RS08185 (NCTC9124_01648) - 1693743..1694489 (+) 747 WP_041789750.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23562.26 Da        Isoelectric Point: 4.8121

>NTDB_id=1127501 FGL12_RS08165 WP_012130666.1 1689072..1689737(-) (comEA/celA/cilE) [Streptococcus gordonii strain NCTC9124]
MIENLIEKAKQYKIALGLSLLGAIAASFILLQGRDQGGTDVQQLTEQTSSSSSYMNEKSNKSNEISQSETEDQLVTVDVK
GAVKKPGVYQLQSNSRVHDALEKAGGLTDEADLKSINQAQKLSDEAVVYVAKVGENAVDVTTSAPTSATSGTGQTKSALV
NLNTATEADFQTISGIGQKRAQDIIAYREANGRFKSVDDLKNVSGIGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1127501 FGL12_RS08165 WP_012130666.1 1689072..1689737(-) (comEA/celA/cilE) [Streptococcus gordonii strain NCTC9124]
ATGATAGAAAATTTGATAGAAAAAGCAAAGCAATATAAAATTGCTCTAGGTCTCAGTCTATTAGGAGCGATTGCAGCAAG
CTTTATTTTACTACAGGGAAGAGACCAAGGGGGGACAGATGTTCAGCAATTGACAGAGCAAACTTCTTCCTCTAGTTCAT
ATATGAATGAAAAAAGTAACAAGAGCAACGAGATCAGTCAATCCGAGACAGAAGATCAGTTGGTTACAGTTGATGTCAAG
GGGGCGGTAAAAAAGCCTGGTGTCTATCAGTTGCAGTCTAATAGTCGGGTTCATGATGCTTTAGAAAAGGCTGGTGGTTT
AACTGACGAAGCTGACTTAAAATCCATCAATCAGGCTCAGAAACTAAGTGATGAGGCAGTAGTATATGTGGCCAAGGTCG
GAGAAAATGCTGTAGATGTTACAACGAGTGCTCCTACAAGTGCAACATCAGGCACCGGTCAGACAAAATCAGCACTTGTC
AATCTTAATACAGCAACAGAAGCAGACTTTCAAACTATTTCTGGTATCGGCCAAAAACGAGCACAGGATATTATTGCTTA
TCGAGAAGCCAATGGTAGGTTTAAGTCTGTAGATGATCTGAAAAATGTATCAGGTATTGGGGCCAAAACTCTAGAAAAAT
TAAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(158-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AYM0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

48.869

100

0.489
  comEA/celA/cilE Streptococcus mitis NCTC 12261

49.091

99.548

0.489
  comEA/celA/cilE Streptococcus pneumoniae D39

48.636

99.548

0.484
  comEA/celA/cilE Streptococcus pneumoniae R6

48.636

99.548

0.484
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.636

99.548

0.484
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.636

99.548

0.484
  comEA Streptococcus thermophilus LMD-9

56.757

66.968

0.38
  comEA Latilactobacillus sakei subsp. sakei 23K

35

100

0.38
  comEA Bacillus subtilis subsp. subtilis str. 168

38.863

95.475

0.371

Multiple sequence alignment