Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGL04_RS10315 Genome accession   NZ_LR594035
Coordinates   1997339..1998598 (-) Length   419 a.a.
NCBI ID   WP_138069090.1    Uniprot ID   A0A4U9ZQZ2
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1992339..2003598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS10285 (NCTC5385_02226) - 1992501..1994063 (-) 1563 WP_138069087.1 DUF2079 domain-containing protein -
  FGL04_RS10290 (NCTC5385_02227) - 1994191..1994496 (-) 306 WP_003084435.1 DUF1292 domain-containing protein -
  FGL04_RS10295 (NCTC5385_02228) ruvX 1994507..1994926 (-) 420 WP_077323211.1 Holliday junction resolvase RuvX -
  FGL04_RS10300 (NCTC5385_02229) - 1994923..1995192 (-) 270 WP_003083367.1 IreB family regulatory phosphoprotein -
  FGL04_RS10305 (NCTC5385_02230) spx 1995304..1995702 (-) 399 WP_138069088.1 transcriptional regulator Spx -
  FGL04_RS10310 (NCTC5385_02231) recA 1996107..1997249 (-) 1143 WP_138069089.1 recombinase RecA Machinery gene
  FGL04_RS10315 (NCTC5385_02232) cinA 1997339..1998598 (-) 1260 WP_138069090.1 competence/damage-inducible protein A Machinery gene
  FGL04_RS10320 (NCTC5385_02233) - 1998714..1999268 (-) 555 WP_138069091.1 DNA-3-methyladenine glycosylase I -
  FGL04_RS10325 (NCTC5385_02234) ruvA 1999275..1999868 (-) 594 WP_138069092.1 Holliday junction branch migration protein RuvA -
  FGL04_RS10330 (NCTC5385_02235) - 1999870..2001093 (-) 1224 WP_138069093.1 MFS transporter -
  FGL04_RS10335 (NCTC5385_02236) mutL 2001104..2003071 (-) 1968 WP_138069094.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45851.63 Da        Isoelectric Point: 5.5836

>NTDB_id=1127323 FGL04_RS10315 WP_138069090.1 1997339..1998598(-) (cinA) [Streptococcus pseudoporcinus strain NCTC5385]
MKAEIVTVGTEILTGQILNTNAQFLSEKMAEIGVDIYFQTAVGDNKDRLLEVLAIASKRSDLVILCGGLGPTEDDLTKQT
LASFLGRDLIFDKEARDKLDRFFASRPQSSRTTNNERQAQLIEGSRPIQNITGLAVGGLVESGGVSYVVLPGPPSELIPM
VNQQLLPMLTATQTRLYSRVLRFFGIGESQLVTVLANFISEQTDPTIAPYAKIGEVTLRLSTKALELIEANQKLDKLEKA
ILDTPTMDSIPLRQFFYGYGEDNSLSREVVQLLKQKKKKLTAAESLTAGLFQSTLANYAGISEFFSGGFVTYSMLEKSRM
LKIPLSDLQANGVVSHYTAREMAEKARLLTESDIGISLTGVAGPDSLEGHEAGTVFIGISTEEKTDSIQIAIGGRTRFDI
RYIATLHAFNLVRKTLLKS

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1127323 FGL04_RS10315 WP_138069090.1 1997339..1998598(-) (cinA) [Streptococcus pseudoporcinus strain NCTC5385]
ATGAAAGCGGAGATTGTTACAGTAGGCACAGAGATCTTAACTGGTCAAATTCTCAATACGAATGCTCAGTTTTTATCCGA
AAAAATGGCTGAGATAGGAGTTGATATCTATTTTCAAACAGCCGTCGGGGACAACAAAGATCGTTTGCTGGAGGTTCTTG
CCATAGCAAGTAAACGTAGTGATCTTGTTATTCTGTGTGGAGGCCTTGGTCCAACAGAAGATGATTTAACCAAGCAAACA
TTAGCAAGTTTCTTGGGGCGTGATTTGATTTTCGACAAAGAGGCTAGGGATAAATTGGATCGCTTTTTTGCTTCTCGTCC
GCAAAGTTCGCGTACTACTAATAATGAGAGGCAGGCGCAGTTGATTGAAGGTTCAAGACCTATTCAAAATATTACGGGAC
TAGCGGTAGGAGGTTTGGTGGAGAGTGGCGGTGTTTCTTATGTTGTCTTACCTGGTCCTCCTTCTGAATTGATACCAATG
GTTAATCAACAGTTATTACCGATGCTGACTGCGACTCAGACTAGGCTTTATTCGCGTGTATTACGCTTTTTTGGTATTGG
TGAAAGTCAACTAGTCACTGTTCTAGCCAACTTCATATCTGAGCAGACTGATCCAACGATCGCGCCTTATGCCAAGATAG
GTGAAGTAACATTGCGTTTATCCACCAAGGCATTGGAGCTGATAGAGGCAAATCAAAAGCTAGATAAACTTGAAAAAGCT
ATTTTAGATACCCCAACGATGGACAGTATTCCCTTAAGGCAGTTCTTTTATGGTTATGGTGAAGATAATAGTTTATCAAG
GGAAGTTGTCCAGTTACTTAAGCAAAAGAAGAAAAAACTTACAGCAGCTGAGAGTCTAACAGCTGGACTTTTTCAGTCAA
CCTTAGCTAATTATGCAGGGATCTCTGAATTTTTTTCAGGCGGGTTTGTGACCTACAGTATGTTAGAAAAGTCAAGAATG
CTGAAGATTCCTTTATCTGATTTACAAGCTAATGGGGTGGTTAGCCACTATACAGCCCGAGAAATGGCTGAGAAAGCGCG
GTTGTTAACTGAGTCAGATATAGGAATTAGTTTAACAGGTGTTGCAGGGCCAGATTCTCTAGAGGGACATGAGGCGGGAA
CTGTTTTTATCGGTATTTCGACAGAGGAAAAAACAGATTCTATCCAAATTGCAATTGGTGGACGGACTCGTTTTGATATT
CGTTATATAGCAACGCTACATGCTTTTAATTTGGTCCGAAAAACTTTATTAAAAAGTTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9ZQZ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

68.825

99.523

0.685
  cinA Streptococcus mitis SK321

68.345

99.523

0.68
  cinA Streptococcus pneumoniae TIGR4

68.345

99.523

0.68
  cinA Streptococcus pneumoniae Rx1

68.345

99.523

0.68
  cinA Streptococcus pneumoniae R6

68.345

99.523

0.68
  cinA Streptococcus pneumoniae D39

68.106

99.523

0.678
  cinA Streptococcus mitis NCTC 12261

67.626

99.523

0.673
  cinA Streptococcus suis isolate S10

52.644

99.284

0.523
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

99.761

0.458

Multiple sequence alignment