Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   FGK94_RS05650 Genome accession   NZ_LR590471
Coordinates   1230057..1230995 (-) Length   312 a.a.
NCBI ID   WP_043029261.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11854     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1225057..1235995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK94_RS05620 (NCTC11854_01155) comGG 1227355..1227717 (-) 363 WP_012677238.1 competence type IV pilus minor pilin ComGG -
  FGK94_RS05625 (NCTC11854_01156) comYF 1227695..1228129 (-) 435 WP_037580631.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGK94_RS05630 (NCTC11854_01157) comGE 1228116..1228358 (-) 243 WP_012677236.1 competence type IV pilus minor pilin ComGE -
  FGK94_RS05635 (NCTC11854_01158) comGD 1228363..1228788 (-) 426 WP_043029263.1 competence type IV pilus minor pilin ComGD -
  FGK94_RS05640 (NCTC11854_01159) comGC/cglC 1228766..1229089 (-) 324 WP_014622142.1 competence type IV pilus major pilin ComGC Machinery gene
  FGK94_RS05645 (NCTC11854_01160) comYB 1229090..1230124 (-) 1035 WP_229297268.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGK94_RS05650 (NCTC11854_01161) comGA/cglA 1230057..1230995 (-) 939 WP_043029261.1 competence type IV pilus ATPase ComGA Machinery gene
  FGK94_RS05655 (NCTC11854_01162) - 1231152..1231820 (-) 669 WP_043029260.1 ATP-binding cassette domain-containing protein -
  FGK94_RS05660 (NCTC11854_01163) - 1231822..1233825 (-) 2004 WP_043029259.1 DUF1430 domain-containing protein -
  FGK94_RS05665 (NCTC11854_01164) - 1234362..1234727 (-) 366 WP_043029258.1 DUF1033 family protein -
  FGK94_RS05670 (NCTC11854_01165) - 1234788..1235834 (-) 1047 WP_172453718.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35185.40 Da        Isoelectric Point: 6.8988

>NTDB_id=1126880 FGK94_RS05650 WP_043029261.1 1230057..1230995(-) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MVQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDGAKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDSSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQQIDQLLAEGHLNTKQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1126880 FGK94_RS05650 WP_043029261.1 1230057..1230995(-) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGCTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATAAAAAATGACCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTCTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAGTAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAAGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.065

99.359

0.676
  comYA Streptococcus mutans UA140

63.023

99.679

0.628
  comYA Streptococcus mutans UA159

63.023

99.679

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.29

99.359

0.609
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.679

0.526
  comGA Latilactobacillus sakei subsp. sakei 23K

39.661

94.551

0.375

Multiple sequence alignment