Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ALT761_RS15460 Genome accession   NZ_LR136958
Coordinates   3585482..3586690 (+) Length   402 a.a.
NCBI ID   WP_129739864.1    Uniprot ID   A0A448Y231
Organism   Alteromonas sp. 76-1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3580482..3591690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ALT761_RS15435 (ALT761_03151) ampE 3581226..3582095 (-) 870 WP_129739859.1 beta-lactamase regulator AmpE -
  ALT761_RS15440 (ALT761_03152) ampD 3582166..3582726 (-) 561 WP_129739860.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ALT761_RS15445 (ALT761_03153) - 3583229..3583759 (+) 531 WP_129739861.1 TIGR02281 family clan AA aspartic protease -
  ALT761_RS15450 (ALT761_03154) nadC 3583778..3584632 (+) 855 WP_129739862.1 carboxylating nicotinate-nucleotide diphosphorylase -
  ALT761_RS15455 (ALT761_03155) - 3584996..3585415 (+) 420 WP_129739863.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  ALT761_RS15460 (ALT761_03156) pilC 3585482..3586690 (+) 1209 WP_129739864.1 type II secretion system F family protein Machinery gene
  ALT761_RS15465 (ALT761_03157) pilD 3586793..3587698 (+) 906 WP_129739865.1 A24 family peptidase Machinery gene
  ALT761_RS15470 (ALT761_03158) coaE 3587698..3588372 (+) 675 WP_232043474.1 dephospho-CoA kinase -
  ALT761_RS15475 (ALT761_03159) zapD 3588501..3589253 (+) 753 WP_126873773.1 cell division protein ZapD -
  ALT761_RS15480 (ALT761_03160) yacG 3589295..3589522 (+) 228 WP_129739866.1 DNA gyrase inhibitor YacG -
  ALT761_RS15485 (ALT761_03161) - 3589533..3590411 (+) 879 WP_129739867.1 aspartoacylase -
  ALT761_RS15490 (ALT761_03162) mutT 3590538..3590933 (-) 396 WP_129739868.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 43742.38 Da        Isoelectric Point: 9.8687

>NTDB_id=1125813 ALT761_RS15460 WP_129739864.1 3585482..3586690(+) (pilC) [Alteromonas sp. 76-1]
MKAAIVYEWQGKDGRGNSRKGEISAANLKEAKMQLRKQGVSVRKVKKQQKSLFSRGGQKITAADISVFSRQIATMLAAGV
TLIQSLDMISQGHAKASMRKLLGDITNEVRSGNPLSNSLRKHPEYFDDLYCDLVYTGEQSGALETIYDRIATYKEKAEAL
KSKIKKAMFYPVAVVVVALIVTTILLVFVVPQFEEIFSSFGAELPAFTLFVLAISNFVQSYGIFIGIGIGIAGYMFMRVH
KKSQNFRDKVDRAVLKIPVIGEILKKASIARFTRTLATTFAAGVPLIGALESAAGASGNAVFRDAIMFMRKEVAGGMPMH
TSMRATNVFPDMVTQMVAIGEESGSVDSMLSKIATIYEAEVDDMVDGLTSLLEPMIMAVLGVVIGGLIVAMYLPIFEMGN
VV

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=1125813 ALT761_RS15460 WP_129739864.1 3585482..3586690(+) (pilC) [Alteromonas sp. 76-1]
GTGAAGGCTGCAATAGTTTACGAATGGCAAGGTAAAGATGGGCGAGGTAACAGCCGCAAAGGTGAGATATCGGCTGCCAA
CCTTAAAGAAGCCAAAATGCAACTTCGTAAACAAGGTGTTTCAGTCAGAAAAGTAAAAAAACAGCAGAAATCCCTATTTA
GTCGTGGCGGCCAAAAAATTACCGCTGCAGACATTTCAGTATTTTCACGCCAAATTGCCACTATGTTGGCTGCTGGTGTT
ACCCTTATCCAATCTTTAGACATGATATCACAAGGTCATGCTAAAGCATCGATGCGGAAATTGCTCGGAGATATTACAAA
CGAAGTCCGCTCAGGAAACCCCTTATCAAATTCACTGCGTAAACACCCTGAATATTTTGACGATTTATACTGTGACTTGG
TTTACACCGGAGAACAGTCTGGTGCGCTTGAAACTATTTATGACCGAATTGCCACCTATAAAGAAAAAGCAGAAGCACTG
AAATCAAAAATTAAAAAGGCGATGTTTTACCCTGTTGCTGTGGTGGTAGTCGCGCTTATAGTAACCACTATATTGCTAGT
TTTTGTTGTACCTCAATTTGAAGAAATTTTTAGTAGTTTTGGGGCAGAGCTTCCTGCCTTTACACTCTTTGTGCTCGCCA
TCTCAAATTTTGTGCAAAGTTACGGGATATTTATAGGCATCGGAATTGGCATAGCTGGCTACATGTTTATGCGCGTTCAC
AAAAAAAGTCAAAACTTTCGCGATAAAGTTGATAGAGCTGTTCTCAAAATCCCCGTCATTGGGGAAATACTTAAAAAAGC
GAGTATCGCGCGATTTACTCGCACACTAGCAACCACCTTTGCCGCAGGTGTACCTCTAATTGGCGCACTTGAATCGGCTG
CTGGCGCGTCGGGTAATGCGGTCTTTAGAGACGCCATCATGTTTATGCGAAAAGAAGTGGCAGGCGGCATGCCAATGCAT
ACATCAATGCGCGCTACCAATGTATTTCCTGATATGGTGACGCAGATGGTTGCCATCGGTGAAGAGTCTGGCTCAGTTGA
CTCTATGTTAAGCAAAATTGCTACCATATATGAAGCTGAAGTGGATGATATGGTCGATGGCTTAACCAGCTTATTAGAGC
CAATGATCATGGCTGTGCTAGGCGTGGTAATTGGCGGCCTTATCGTTGCGATGTACCTTCCCATATTTGAAATGGGTAAT
GTGGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(68-191)

Type II secretion system (T2SS), protein F (T2SSF)

(272-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448Y231

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

58.69

98.756

0.58
  pilC Acinetobacter baumannii D1279779

52.5

99.502

0.522
  pilC Acinetobacter baylyi ADP1

51.005

99.005

0.505
  pilC Legionella pneumophila strain ERS1305867

50.754

99.005

0.502
  pilC Vibrio cholerae strain A1552

46.717

98.507

0.46
  pilC Vibrio campbellii strain DS40M4

44.612

99.254

0.443
  pilG Neisseria meningitidis 44/76-A

44.125

95.274

0.42
  pilG Neisseria gonorrhoeae MS11

43.864

95.274

0.418
  pilC Thermus thermophilus HB27

36.725

100

0.368

Multiple sequence alignment